ProfileGDS5420 / 232311_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 81% 68% 70% 67% 78% 68% 65% 70% 81% 67% 75% 67% 77% 68% 71% 79% 77% 73% 89% 84% 68% 72% 70% 70% 71% 69% 65% 68% 69% 66% 86% 66% 78% 79% 71% 77% 70% 66% 76% 71% 76% 66% 74% 73% 74% 80% 76% 74% 71% 72% 65% 69% 80% 87% 65% 76% 66% 75% 79% 75% 73% 80% 71% 65% 69% 70% 80% 77% 65% 75% 64% 66% 71% 69% 87% 75% 68% 60% 78% 76% 66% 67% 71% 78% 64% 65% 68% 69% 65% 69% 78% 68% 77% 80% 59% 77% 80% 63% 67% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1164.2681
GSM1296119B_lesional_pre-dose517.6968
GSM1296076C_lesional_pre-dose559.1270
GSM1296092D_lesional_pre-dose473.2267
GSM1296103E_lesional_pre-dose923.1378
GSM1296078F_lesional_pre-dose476.8368
GSM1296107G_lesional_pre-dose427.7765
GSM1296109H_lesional_pre-dose590.6170
GSM1296080I_lesional_pre-dose1167.2581
GSM1296090J_lesional_pre-dose460.5367
GSM1296074K_lesional_pre-dose776.9675
GSM1296111L_lesional_pre-dose479.667
GSM1296099M_lesional_pre-dose883.4977
GSM1296086O_lesional_pre-dose503.568
GSM1296117P_lesional_pre-dose605.8471
GSM1296113Q_lesional_pre-dose978.5979
GSM1296096R_lesional_pre-dose869.5777
GSM1296105S_lesional_pre-dose682.7973
GSM1296098T_lesional_pre-dose1977.0989
GSM1296101U_lesional_pre-dose1399.6184
GSM1296121V_lesional_pre-dose508.8568
GSM1296088W_lesional_pre-dose654.1872
GSM1296082X_lesional_pre-dose558.6870
GSM1296115Y_lesional_pre-dose575.570
GSM1296084Z_lesional_pre-dose627.2371
GSM1296072B_lesional_day8540.869
GSM1296069L_lesional_day8445.8365
GSM1296071P_lesional_day8525.5268
GSM1296070Y_lesional_day8535.8669
GSM1296073V_lesional_day8434.1966
GSM1296034A_lesional_day151562.2986
GSM1296041G_lesional_day15443.5666
GSM1296035R_lesional_day15961.7678
GSM1296038U_lesional_day151028.1679
GSM1296047B_lesional_day15618.8771
GSM1296039E_lesional_day15872.3777
GSM1296042H_lesional_day15570.470
GSM1296043L_lesional_day15480.8466
GSM1296037M_lesional_day15803.5576
GSM1296046P_lesional_day15619.1671
GSM1296044Q_lesional_day15827.2576
GSM1296045Y_lesional_day15461.6666
GSM1296025C_lesional_day15720.7674
GSM1296033D_lesional_day15680.1473
GSM1296027I_lesional_day15733.1274
GSM1296032J_lesional_day151085.1780
GSM1296024K_lesional_day15816.6276
GSM1296031W_lesional_day15750.5174
GSM1296028X_lesional_day15619.5271
GSM1296029Z_lesional_day15657.1672
GSM1296026F_lesional_day15413.565
GSM1296030O_lesional_day15542.7769
GSM1296040S_lesional_day151068.6380
GSM1296036T_lesional_day151622.5287
GSM1296048V_lesional_day15423.2265
GSM1296059A_lesional_day43850.2376
GSM1296066G_lesional_day43453.9266
GSM1296060R_lesional_day43776.8475
GSM1296063U_lesional_day43982.4279
GSM1296064E_lesional_day43745.1575
GSM1296067H_lesional_day4368573
GSM1296062M_lesional_day431059.380
GSM1296068Q_lesional_day43601.1171
GSM1296050C_lesional_day43414.765
GSM1296057D_lesional_day43541.5669
GSM1296052I_lesional_day43562.4770
GSM1296054J_lesional_day431046.3580
GSM1296049K_lesional_day43855.277
GSM1296055W_lesional_day43439.3465
GSM1296053X_lesional_day43807.1475
GSM1296058Z_lesional_day43414.7364
GSM1296051F_lesional_day43436.766
GSM1296056O_lesional_day43602.8171
GSM1296065S_lesional_day43531.1169
GSM1296061T_lesional_day431655.6487
GSM1296095A_non-lesional_pre-dose756.8675
GSM1296120B_non-lesional_pre-dose521.6168
GSM1296077C_non-lesional_pre-dose315.6860
GSM1296093D_non-lesional_pre-dose923.4778
GSM1296104E_non-lesional_pre-dose815.676
GSM1296079F_non-lesional_pre-dose437.9266
GSM1296108G_non-lesional_pre-dose478.9667
GSM1296110H_non-lesional_pre-dose635.871
GSM1296081I_non-lesional_pre-dose980.9678
GSM1296091J_non-lesional_pre-dose400.6164
GSM1296075K_non-lesional_pre-dose390.3765
GSM1296112L_non-lesional_pre-dose514.6668
GSM1296100M_non-lesional_pre-dose543.0869
GSM1296087O_non-lesional_pre-dose421.7365
GSM1296118P_non-lesional_pre-dose539.0669
GSM1296114Q_non-lesional_pre-dose930.0178
GSM1296097R_non-lesional_pre-dose518.0968
GSM1296106S_non-lesional_pre-dose876.0777
GSM1296102U_non-lesional_pre-dose1026.7180
GSM1296122V_non-lesional_pre-dose309.8459
GSM1296089W_non-lesional_pre-dose889.7977
GSM1296083X_non-lesional_pre-dose1095.280
GSM1296116Y_non-lesional_pre-dose400.5563
GSM1296085Z_non-lesional_pre-dose472.267