ProfileGDS5420 / 233488_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 52% 63% 76% 66% 44% 69% 62% 48% 27% 76% 77% 68% 43% 54% 64% 73% 66% 50% 46% 68% 55% 49% 78% 73% 62% 75% 67% 54% 80% 82% 40% 83% 75% 64% 52% 65% 69% 65% 29% 74% 63% 78% 38% 59% 35% 9% 42% 47% 32% 41% 42% 42% 54% 36% 78% 58% 74% 51% 85% 74% 36% 37% 49% 32% 60% 32% 31% 42% 40% 42% 87% 57% 75% 87% 38% 65% 48% 45% 20% 73% 42% 61% 57% 30% 79% 67% 56% 36% 59% 35% 63% 71% 58% 64% 40% 53% 43% 68% 24% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose200.3952
GSM1296119B_lesional_pre-dose383.9163
GSM1296076C_lesional_pre-dose816.0776
GSM1296092D_lesional_pre-dose425.8766
GSM1296103E_lesional_pre-dose112.8244
GSM1296078F_lesional_pre-dose508.569
GSM1296107G_lesional_pre-dose349.0262
GSM1296109H_lesional_pre-dose166.5248
GSM1296080I_lesional_pre-dose34.0127
GSM1296090J_lesional_pre-dose848.3376
GSM1296074K_lesional_pre-dose860.9577
GSM1296111L_lesional_pre-dose498.768
GSM1296099M_lesional_pre-dose114.5843
GSM1296086O_lesional_pre-dose202.9954
GSM1296117P_lesional_pre-dose411.5464
GSM1296113Q_lesional_pre-dose692.5873
GSM1296096R_lesional_pre-dose439.9766
GSM1296105S_lesional_pre-dose179.9950
GSM1296098T_lesional_pre-dose140.4746
GSM1296101U_lesional_pre-dose515.3868
GSM1296121V_lesional_pre-dose235.6755
GSM1296088W_lesional_pre-dose154.2149
GSM1296082X_lesional_pre-dose932.4478
GSM1296115Y_lesional_pre-dose698.8473
GSM1296084Z_lesional_pre-dose347.4162
GSM1296072B_lesional_day8755.5575
GSM1296069L_lesional_day8505.4167
GSM1296071P_lesional_day8247.5754
GSM1296070Y_lesional_day81032.6480
GSM1296073V_lesional_day81240.9282
GSM1296034A_lesional_day1598.0740
GSM1296041G_lesional_day151246.6183
GSM1296035R_lesional_day15777.8175
GSM1296038U_lesional_day15403.7864
GSM1296047B_lesional_day15203.0352
GSM1296039E_lesional_day15416.7365
GSM1296042H_lesional_day15541.2569
GSM1296043L_lesional_day15451.1965
GSM1296037M_lesional_day1548.0229
GSM1296046P_lesional_day15724.1574
GSM1296044Q_lesional_day15403.0763
GSM1296045Y_lesional_day15935.9878
GSM1296025C_lesional_day1578.6638
GSM1296033D_lesional_day15306.1459
GSM1296027I_lesional_day1555.2735
GSM1296032J_lesional_day158.459
GSM1296024K_lesional_day1595.8942
GSM1296031W_lesional_day15153.0447
GSM1296028X_lesional_day1552.2932
GSM1296029Z_lesional_day1598.0441
GSM1296026F_lesional_day1597.7942
GSM1296030O_lesional_day1589.6342
GSM1296040S_lesional_day15228.1954
GSM1296036T_lesional_day1577.336
GSM1296048V_lesional_day15916.0478
GSM1296059A_lesional_day43271.5158
GSM1296066G_lesional_day43731.5474
GSM1296060R_lesional_day43190.3351
GSM1296063U_lesional_day431458.5485
GSM1296064E_lesional_day43731.874
GSM1296067H_lesional_day4384.9336
GSM1296062M_lesional_day4376.4937
GSM1296068Q_lesional_day43192.9249
GSM1296050C_lesional_day4356.6432
GSM1296057D_lesional_day43331.9560
GSM1296052I_lesional_day4347.7332
GSM1296054J_lesional_day4353.2631
GSM1296049K_lesional_day43103.4242
GSM1296055W_lesional_day4396.2240
GSM1296053X_lesional_day43100.6242
GSM1296058Z_lesional_day431688.0987
GSM1296051F_lesional_day43244.0457
GSM1296056O_lesional_day43782.9775
GSM1296065S_lesional_day431719.5187
GSM1296061T_lesional_day4381.7338
GSM1296095A_non-lesional_pre-dose408.7165
GSM1296120B_non-lesional_pre-dose164.3348
GSM1296077C_non-lesional_pre-dose117.1545
GSM1296093D_non-lesional_pre-dose24.6820
GSM1296104E_non-lesional_pre-dose680.4973
GSM1296079F_non-lesional_pre-dose102.8242
GSM1296108G_non-lesional_pre-dose344.2961
GSM1296110H_non-lesional_pre-dose293.0257
GSM1296081I_non-lesional_pre-dose41.3630
GSM1296091J_non-lesional_pre-dose1036.8879
GSM1296075K_non-lesional_pre-dose444.7267
GSM1296112L_non-lesional_pre-dose278.2856
GSM1296100M_non-lesional_pre-dose72.6136
GSM1296087O_non-lesional_pre-dose269.8159
GSM1296118P_non-lesional_pre-dose84.7535
GSM1296114Q_non-lesional_pre-dose404.6463
GSM1296097R_non-lesional_pre-dose615.6871
GSM1296106S_non-lesional_pre-dose291.3958
GSM1296102U_non-lesional_pre-dose427.8264
GSM1296122V_non-lesional_pre-dose103.1540
GSM1296089W_non-lesional_pre-dose218.1253
GSM1296083X_non-lesional_pre-dose112.9343
GSM1296116Y_non-lesional_pre-dose529.3868
GSM1296085Z_non-lesional_pre-dose30.824