ProfileGDS5420 / 233671_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 1% 10% 0% 4% 4% 9% 9% 2% 10% 10% 9% 1% 8% 15% 3% 9% 1% 5% 7% 5% 18% 6% 7% 11% 2% 13% 4% 13% 9% 14% 11% 10% 9% 8% 10% 15% 14% 9% 20% 16% 0% 8% 2% 22% 6% 13% 17% 0% 10% 4% 13% 5% 7% 8% 14% 7% 11% 20% 1% 5% 19% 6% 6% 7% 9% 25% 7% 13% 22% 0% 1% 8% 2% 18% 7% 32% 37% 2% 9% 12% 8% 24% 16% 27% 26% 21% 5% 19% 29% 46% 6% 2% 17% 33% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1.581
GSM1296119B_lesional_pre-dose12.210
GSM1296076C_lesional_pre-dose0.120
GSM1296092D_lesional_pre-dose3.364
GSM1296103E_lesional_pre-dose
GSM1296078F_lesional_pre-dose4.464
GSM1296107G_lesional_pre-dose11.319
GSM1296109H_lesional_pre-dose10.029
GSM1296080I_lesional_pre-dose
GSM1296090J_lesional_pre-dose2.452
GSM1296074K_lesional_pre-dose910
GSM1296111L_lesional_pre-dose12.7910
GSM1296099M_lesional_pre-dose8.789
GSM1296086O_lesional_pre-dose1.071
GSM1296117P_lesional_pre-dose10.548
GSM1296113Q_lesional_pre-dose24.4315
GSM1296096R_lesional_pre-dose2.663
GSM1296105S_lesional_pre-dose9.499
GSM1296098T_lesional_pre-dose1.711
GSM1296101U_lesional_pre-dose5.685
GSM1296121V_lesional_pre-dose7.637
GSM1296088W_lesional_pre-dose5.245
GSM1296082X_lesional_pre-dose17.4818
GSM1296115Y_lesional_pre-dose6.66
GSM1296084Z_lesional_pre-dose8.47
GSM1296072B_lesional_day812.1211
GSM1296069L_lesional_day82.282
GSM1296071P_lesional_day817.3913
GSM1296070Y_lesional_day85.644
GSM1296073V_lesional_day814.9213
GSM1296034A_lesional_day15109
GSM1296041G_lesional_day1517.6914
GSM1296035R_lesional_day158.7211
GSM1296038U_lesional_day159.3310
GSM1296047B_lesional_day1510.939
GSM1296039E_lesional_day158.318
GSM1296042H_lesional_day1512.7210
GSM1296043L_lesional_day1521.1615
GSM1296037M_lesional_day1517.4314
GSM1296046P_lesional_day1511.529
GSM1296044Q_lesional_day1528.3620
GSM1296045Y_lesional_day1524.5416
GSM1296025C_lesional_day150.150
GSM1296033D_lesional_day157.468
GSM1296027I_lesional_day151.652
GSM1296032J_lesional_day1525.8122
GSM1296024K_lesional_day156.456
GSM1296031W_lesional_day1513.4313
GSM1296028X_lesional_day1517.5917
GSM1296029Z_lesional_day150.180
GSM1296026F_lesional_day1511.4810
GSM1296030O_lesional_day153.694
GSM1296040S_lesional_day1514.7513
GSM1296036T_lesional_day155.945
GSM1296048V_lesional_day158.127
GSM1296059A_lesional_day437.18
GSM1296066G_lesional_day4317.4914
GSM1296060R_lesional_day436.737
GSM1296063U_lesional_day4311.8411
GSM1296064E_lesional_day4323.7520
GSM1296067H_lesional_day431.741
GSM1296062M_lesional_day434.855
GSM1296068Q_lesional_day4329.7219
GSM1296050C_lesional_day437.626
GSM1296057D_lesional_day435.756
GSM1296052I_lesional_day436.467
GSM1296054J_lesional_day439.479
GSM1296049K_lesional_day4333.3125
GSM1296055W_lesional_day437.537
GSM1296053X_lesional_day4313.3413
GSM1296058Z_lesional_day4322.6822
GSM1296051F_lesional_day430.170
GSM1296056O_lesional_day430.891
GSM1296065S_lesional_day437.888
GSM1296061T_lesional_day433.022
GSM1296095A_non-lesional_pre-dose
GSM1296120B_non-lesional_pre-dose2418
GSM1296077C_non-lesional_pre-dose7.617
GSM1296093D_non-lesional_pre-dose59.1732
GSM1296104E_non-lesional_pre-dose72.8837
GSM1296079F_non-lesional_pre-dose2.432
GSM1296108G_non-lesional_pre-dose9.679
GSM1296110H_non-lesional_pre-dose16.4312
GSM1296081I_non-lesional_pre-dose6.648
GSM1296091J_non-lesional_pre-dose
GSM1296075K_non-lesional_pre-dose30.3124
GSM1296112L_non-lesional_pre-dose24.9716
GSM1296100M_non-lesional_pre-dose40.6227
GSM1296087O_non-lesional_pre-dose
GSM1296118P_non-lesional_pre-dose45.8626
GSM1296114Q_non-lesional_pre-dose32.6121
GSM1296097R_non-lesional_pre-dose4.825
GSM1296106S_non-lesional_pre-dose23.3719
GSM1296102U_non-lesional_pre-dose44.8129
GSM1296122V_non-lesional_pre-dose14646
GSM1296089W_non-lesional_pre-dose6.196
GSM1296083X_non-lesional_pre-dose1.722
GSM1296116Y_non-lesional_pre-dose27.0817
GSM1296085Z_non-lesional_pre-dose57.833