ProfileGDS5420 / 233693_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 38% 27% 44% 30% 32% 46% 33% 37% 35% 34% 43% 32% 43% 45% 39% 9% 39% 31% 46% 31% 33% 37% 41% 36% 41% 31% 29% 30% 28% 31% 37% 39% 33% 35% 19% 32% 23% 21% 33% 36% 24% 22% 21% 31% 43% 29% 31% 31% 28% 26% 32% 39% 33% 40% 36% 38% 34% 30% 41% 35% 19% 38% 12% 32% 30% 35% 31% 28% 22% 36% 25% 40% 50% 34% 35% 27% 27% 25% 34% 4% 18% 26% 19% 39% 33% 33% 31% 26% 32% 11% 26% 18% 26% 34% 23% 29% 34% 34% 32% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose80.0738
GSM1296119B_lesional_pre-dose44.1927
GSM1296076C_lesional_pre-dose108.7544
GSM1296092D_lesional_pre-dose41.2230
GSM1296103E_lesional_pre-dose50.8232
GSM1296078F_lesional_pre-dose118.9946
GSM1296107G_lesional_pre-dose67.9633
GSM1296109H_lesional_pre-dose85.7837
GSM1296080I_lesional_pre-dose60.6235
GSM1296090J_lesional_pre-dose56.5434
GSM1296074K_lesional_pre-dose95.4243
GSM1296111L_lesional_pre-dose63.4532
GSM1296099M_lesional_pre-dose113.2243
GSM1296086O_lesional_pre-dose115.645
GSM1296117P_lesional_pre-dose99.9239
GSM1296113Q_lesional_pre-dose14.229
GSM1296096R_lesional_pre-dose83.6139
GSM1296105S_lesional_pre-dose53.3431
GSM1296098T_lesional_pre-dose143.0446
GSM1296101U_lesional_pre-dose50.231
GSM1296121V_lesional_pre-dose63.6333
GSM1296088W_lesional_pre-dose72.3637
GSM1296082X_lesional_pre-dose84.9641
GSM1296115Y_lesional_pre-dose78.236
GSM1296084Z_lesional_pre-dose98.9841
GSM1296072B_lesional_day857.3831
GSM1296069L_lesional_day858.3129
GSM1296071P_lesional_day861.8130
GSM1296070Y_lesional_day852.328
GSM1296073V_lesional_day856.8431
GSM1296034A_lesional_day1579.0137
GSM1296041G_lesional_day1597.3239
GSM1296035R_lesional_day1550.0133
GSM1296038U_lesional_day1564.5935
GSM1296047B_lesional_day1527.5619
GSM1296039E_lesional_day1555.2932
GSM1296042H_lesional_day1537.423
GSM1296043L_lesional_day1532.5721
GSM1296037M_lesional_day1562.7133
GSM1296046P_lesional_day1584.1536
GSM1296044Q_lesional_day1539.224
GSM1296045Y_lesional_day1537.9222
GSM1296025C_lesional_day1526.5821
GSM1296033D_lesional_day1548.3731
GSM1296027I_lesional_day1593.0343
GSM1296032J_lesional_day1544.2629
GSM1296024K_lesional_day1545.4331
GSM1296031W_lesional_day1552.3131
GSM1296028X_lesional_day1539.6228
GSM1296029Z_lesional_day1533.6126
GSM1296026F_lesional_day1554.0132
GSM1296030O_lesional_day1569.0839
GSM1296040S_lesional_day1559.1533
GSM1296036T_lesional_day15101.1440
GSM1296048V_lesional_day1579.5336
GSM1296059A_lesional_day4377.2638
GSM1296066G_lesional_day4373.4434
GSM1296060R_lesional_day4346.9630
GSM1296063U_lesional_day4397.8641
GSM1296064E_lesional_day4364.4435
GSM1296067H_lesional_day4326.0219
GSM1296062M_lesional_day4379.8938
GSM1296068Q_lesional_day4317.6512
GSM1296050C_lesional_day4358.3732
GSM1296057D_lesional_day4343.4530
GSM1296052I_lesional_day4357.135
GSM1296054J_lesional_day4352.1331
GSM1296049K_lesional_day4340.8828
GSM1296055W_lesional_day4328.8522
GSM1296053X_lesional_day4368.9636
GSM1296058Z_lesional_day4328.5725
GSM1296051F_lesional_day4389.8840
GSM1296056O_lesional_day43159.8450
GSM1296065S_lesional_day4362.6934
GSM1296061T_lesional_day4370.935
GSM1296095A_non-lesional_pre-dose35.6227
GSM1296120B_non-lesional_pre-dose47.5227
GSM1296077C_non-lesional_pre-dose32.4225
GSM1296093D_non-lesional_pre-dose65.834
GSM1296104E_non-lesional_pre-dose4.954
GSM1296079F_non-lesional_pre-dose21.7218
GSM1296108G_non-lesional_pre-dose41.2126
GSM1296110H_non-lesional_pre-dose27.4419
GSM1296081I_non-lesional_pre-dose77.4939
GSM1296091J_non-lesional_pre-dose53.8733
GSM1296075K_non-lesional_pre-dose54.6933
GSM1296112L_non-lesional_pre-dose68.8831
GSM1296100M_non-lesional_pre-dose35.626
GSM1296087O_non-lesional_pre-dose47.1432
GSM1296118P_non-lesional_pre-dose15.5911
GSM1296114Q_non-lesional_pre-dose46.6426
GSM1296097R_non-lesional_pre-dose18.5118
GSM1296106S_non-lesional_pre-dose39.2626
GSM1296102U_non-lesional_pre-dose67.6334
GSM1296122V_non-lesional_pre-dose36.4623
GSM1296089W_non-lesional_pre-dose48.7829
GSM1296083X_non-lesional_pre-dose59.4434
GSM1296116Y_non-lesional_pre-dose80.3134
GSM1296085Z_non-lesional_pre-dose55.3432