ProfileGDS5420 / 234212_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 19% 29% 35% 25% 20% 34% 37% 35% 24% 37% 30% 41% 27% 33% 31% 39% 27% 25% 20% 7% 32% 30% 39% 44% 19% 29% 41% 33% 31% 30% 28% 36% 24% 25% 29% 27% 35% 35% 9% 35% 34% 37% 30% 31% 32% 23% 26% 38% 29% 15% 30% 21% 7% 21% 32% 17% 34% 25% 29% 31% 30% 20% 32% 32% 18% 29% 27% 28% 32% 28% 9% 35% 8% 31% 25% 27% 29% 22% 28% 27% 21% 32% 41% 12% 25% 24% 31% 24% 16% 35% 35% 14% 30% 17% 28% 32% 34% 39% 26% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose20.6519
GSM1296119B_lesional_pre-dose49.6729
GSM1296076C_lesional_pre-dose64.7335
GSM1296092D_lesional_pre-dose29.0825
GSM1296103E_lesional_pre-dose22.2320
GSM1296078F_lesional_pre-dose60.1434
GSM1296107G_lesional_pre-dose86.2937
GSM1296109H_lesional_pre-dose74.535
GSM1296080I_lesional_pre-dose29.324
GSM1296090J_lesional_pre-dose67.237
GSM1296074K_lesional_pre-dose41.5430
GSM1296111L_lesional_pre-dose108.4641
GSM1296099M_lesional_pre-dose40.0427
GSM1296086O_lesional_pre-dose51.3933
GSM1296117P_lesional_pre-dose62.8531
GSM1296113Q_lesional_pre-dose107.0739
GSM1296096R_lesional_pre-dose36.4227
GSM1296105S_lesional_pre-dose35.1625
GSM1296098T_lesional_pre-dose30.7220
GSM1296101U_lesional_pre-dose7.187
GSM1296121V_lesional_pre-dose60.2932
GSM1296088W_lesional_pre-dose45.2130
GSM1296082X_lesional_pre-dose74.4739
GSM1296115Y_lesional_pre-dose128.2644
GSM1296084Z_lesional_pre-dose23.9519
GSM1296072B_lesional_day850.0429
GSM1296069L_lesional_day8120.4541
GSM1296071P_lesional_day871.1633
GSM1296070Y_lesional_day860.6731
GSM1296073V_lesional_day85130
GSM1296034A_lesional_day1543.128
GSM1296041G_lesional_day1579.0836
GSM1296035R_lesional_day1526.8324
GSM1296038U_lesional_day1533.325
GSM1296047B_lesional_day1554.2729
GSM1296039E_lesional_day1540.3827
GSM1296042H_lesional_day1576.8535
GSM1296043L_lesional_day1581.2535
GSM1296037M_lesional_day1510.839
GSM1296046P_lesional_day1580.6635
GSM1296044Q_lesional_day1576.9634
GSM1296045Y_lesional_day1595.5137
GSM1296025C_lesional_day1547.4830
GSM1296033D_lesional_day1546.931
GSM1296027I_lesional_day1544.7932
GSM1296032J_lesional_day1527.5523
GSM1296024K_lesional_day1534.3926
GSM1296031W_lesional_day1584.0238
GSM1296028X_lesional_day1543.5729
GSM1296029Z_lesional_day1515.1315
GSM1296026F_lesional_day1548.3130
GSM1296030O_lesional_day1519.7521
GSM1296040S_lesional_day157.977
GSM1296036T_lesional_day1527.5621
GSM1296048V_lesional_day1560.5232
GSM1296059A_lesional_day4316.717
GSM1296066G_lesional_day4372.3334
GSM1296060R_lesional_day4331.5125
GSM1296063U_lesional_day4346.0729
GSM1296064E_lesional_day4349.2931
GSM1296067H_lesional_day4356.2830
GSM1296062M_lesional_day4321.3120
GSM1296068Q_lesional_day4372.5632
GSM1296050C_lesional_day4358.2332
GSM1296057D_lesional_day4318.9118
GSM1296052I_lesional_day4338.7329
GSM1296054J_lesional_day4339.927
GSM1296049K_lesional_day4342.2228
GSM1296055W_lesional_day4356.1932
GSM1296053X_lesional_day4339.6328
GSM1296058Z_lesional_day437.089
GSM1296051F_lesional_day4364.4635
GSM1296056O_lesional_day437.638
GSM1296065S_lesional_day4351.2131
GSM1296061T_lesional_day4335.4425
GSM1296095A_non-lesional_pre-dose37.5327
GSM1296120B_non-lesional_pre-dose53.929
GSM1296077C_non-lesional_pre-dose25.9722
GSM1296093D_non-lesional_pre-dose42.528
GSM1296104E_non-lesional_pre-dose39.4527
GSM1296079F_non-lesional_pre-dose27.0221
GSM1296108G_non-lesional_pre-dose62.5432
GSM1296110H_non-lesional_pre-dose120.9641
GSM1296081I_non-lesional_pre-dose10.812
GSM1296091J_non-lesional_pre-dose31.125
GSM1296075K_non-lesional_pre-dose30.2524
GSM1296112L_non-lesional_pre-dose67.2631
GSM1296100M_non-lesional_pre-dose32.4724
GSM1296087O_non-lesional_pre-dose15.8416
GSM1296118P_non-lesional_pre-dose80.8335
GSM1296114Q_non-lesional_pre-dose81.1835
GSM1296097R_non-lesional_pre-dose13.2314
GSM1296106S_non-lesional_pre-dose52.8430
GSM1296102U_non-lesional_pre-dose19.517
GSM1296122V_non-lesional_pre-dose49.0628
GSM1296089W_non-lesional_pre-dose58.0532
GSM1296083X_non-lesional_pre-dose58.4734
GSM1296116Y_non-lesional_pre-dose103.939
GSM1296085Z_non-lesional_pre-dose35.8326