ProfileGDS5420 / 234711_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 36% 44% 47% 46% 44% 50% 31% 36% 46% 40% 40% 32% 35% 43% 36% 37% 40% 29% 38% 21% 39% 37% 38% 32% 26% 34% 27% 30% 30% 38% 32% 34% 32% 31% 27% 26% 25% 15% 35% 35% 21% 16% 40% 41% 26% 16% 41% 38% 30% 26% 47% 31% 44% 21% 44% 38% 24% 32% 37% 43% 29% 26% 28% 31% 27% 29% 17% 40% 43% 33% 37% 41% 40% 32% 28% 42% 43% 40% 24% 34% 44% 29% 23% 41% 33% 40% 24% 39% 37% 29% 31% 35% 31% 36% 40% 24% 18% 20% 27% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose69.5636
GSM1296119B_lesional_pre-dose125.344
GSM1296076C_lesional_pre-dose130.4447
GSM1296092D_lesional_pre-dose114.2446
GSM1296103E_lesional_pre-dose115.3344
GSM1296078F_lesional_pre-dose150.5650
GSM1296107G_lesional_pre-dose60.231
GSM1296109H_lesional_pre-dose80.8636
GSM1296080I_lesional_pre-dose122.7946
GSM1296090J_lesional_pre-dose81.4240
GSM1296074K_lesional_pre-dose76.1540
GSM1296111L_lesional_pre-dose66.6732
GSM1296099M_lesional_pre-dose67.1835
GSM1296086O_lesional_pre-dose103.1143
GSM1296117P_lesional_pre-dose84.9436
GSM1296113Q_lesional_pre-dose9737
GSM1296096R_lesional_pre-dose9040
GSM1296105S_lesional_pre-dose45.0829
GSM1296098T_lesional_pre-dose88.7338
GSM1296101U_lesional_pre-dose25.6821
GSM1296121V_lesional_pre-dose90.1139
GSM1296088W_lesional_pre-dose71.6137
GSM1296082X_lesional_pre-dose69.3938
GSM1296115Y_lesional_pre-dose58.8832
GSM1296084Z_lesional_pre-dose37.8826
GSM1296072B_lesional_day868.2734
GSM1296069L_lesional_day848.6927
GSM1296071P_lesional_day860.430
GSM1296070Y_lesional_day860.2630
GSM1296073V_lesional_day882.5938
GSM1296034A_lesional_day1558.5332
GSM1296041G_lesional_day1568.3234
GSM1296035R_lesional_day1546.7732
GSM1296038U_lesional_day1550.9931
GSM1296047B_lesional_day1547.927
GSM1296039E_lesional_day1536.6926
GSM1296042H_lesional_day1541.4925
GSM1296043L_lesional_day1521.1615
GSM1296037M_lesional_day1571.5435
GSM1296046P_lesional_day1581.0935
GSM1296044Q_lesional_day1532.5621
GSM1296045Y_lesional_day1524.3616
GSM1296025C_lesional_day1590.7540
GSM1296033D_lesional_day1594.0441
GSM1296027I_lesional_day1530.5226
GSM1296032J_lesional_day1516.9316
GSM1296024K_lesional_day1589.5541
GSM1296031W_lesional_day1582.9238
GSM1296028X_lesional_day1546.9230
GSM1296029Z_lesional_day1534.6626
GSM1296026F_lesional_day15138.3647
GSM1296030O_lesional_day1540.331
GSM1296040S_lesional_day15122.844
GSM1296036T_lesional_day1527.7821
GSM1296048V_lesional_day15123.9644
GSM1296059A_lesional_day4373.9538
GSM1296066G_lesional_day4338.0924
GSM1296060R_lesional_day4352.5132
GSM1296063U_lesional_day4378.4337
GSM1296064E_lesional_day43106.5243
GSM1296067H_lesional_day4354.2929
GSM1296062M_lesional_day4335.0826
GSM1296068Q_lesional_day4355.6728
GSM1296050C_lesional_day4353.3231
GSM1296057D_lesional_day4335.7927
GSM1296052I_lesional_day4336.8329
GSM1296054J_lesional_day4320.1917
GSM1296049K_lesional_day4392.4440
GSM1296055W_lesional_day43119.0943
GSM1296053X_lesional_day4358.8333
GSM1296058Z_lesional_day4369.6437
GSM1296051F_lesional_day4394.1341
GSM1296056O_lesional_day4381.9140
GSM1296065S_lesional_day4353.9632
GSM1296061T_lesional_day4343.0428
GSM1296095A_non-lesional_pre-dose98.0342
GSM1296120B_non-lesional_pre-dose121.9143
GSM1296077C_non-lesional_pre-dose87.6240
GSM1296093D_non-lesional_pre-dose32.1324
GSM1296104E_non-lesional_pre-dose60.7134
GSM1296079F_non-lesional_pre-dose112.6444
GSM1296108G_non-lesional_pre-dose51.4229
GSM1296110H_non-lesional_pre-dose35.823
GSM1296081I_non-lesional_pre-dose86.541
GSM1296091J_non-lesional_pre-dose54.1533
GSM1296075K_non-lesional_pre-dose84.1240
GSM1296112L_non-lesional_pre-dose43.3624
GSM1296100M_non-lesional_pre-dose90.2539
GSM1296087O_non-lesional_pre-dose65.3637
GSM1296118P_non-lesional_pre-dose56.129
GSM1296114Q_non-lesional_pre-dose63.8531
GSM1296097R_non-lesional_pre-dose66.2835
GSM1296106S_non-lesional_pre-dose56.4831
GSM1296102U_non-lesional_pre-dose75.9236
GSM1296122V_non-lesional_pre-dose102.4940
GSM1296089W_non-lesional_pre-dose35.1724
GSM1296083X_non-lesional_pre-dose19.8918
GSM1296116Y_non-lesional_pre-dose32.8820
GSM1296085Z_non-lesional_pre-dose39.0827