ProfileGDS5420 / 235475_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 30% 40% 51% 48% 36% 47% 44% 37% 28% 49% 44% 43% 36% 39% 41% 44% 32% 37% 31% 28% 45% 45% 45% 41% 45% 49% 46% 42% 41% 42% 40% 43% 40% 43% 53% 46% 48% 44% 25% 49% 49% 43% 46% 42% 49% 38% 44% 32% 45% 43% 42% 46% 35% 41% 42% 22% 46% 41% 43% 40% 38% 31% 49% 45% 45% 41% 49% 41% 36% 43% 39% 41% 37% 45% 33% 47% 50% 46% 51% 51% 37% 48% 44% 39% 49% 49% 43% 41% 51% 51% 50% 43% 42% 42% 43% 43% 41% 47% 52% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose46.6330
GSM1296119B_lesional_pre-dose101.1440
GSM1296076C_lesional_pre-dose164.8651
GSM1296092D_lesional_pre-dose133.6548
GSM1296103E_lesional_pre-dose69.9536
GSM1296078F_lesional_pre-dose130.9447
GSM1296107G_lesional_pre-dose132.2844
GSM1296109H_lesional_pre-dose87.8737
GSM1296080I_lesional_pre-dose37.3628
GSM1296090J_lesional_pre-dose146.1849
GSM1296074K_lesional_pre-dose97.4744
GSM1296111L_lesional_pre-dose123.5343
GSM1296099M_lesional_pre-dose72.5736
GSM1296086O_lesional_pre-dose77.9639
GSM1296117P_lesional_pre-dose112.3441
GSM1296113Q_lesional_pre-dose145.4444
GSM1296096R_lesional_pre-dose52.9132
GSM1296105S_lesional_pre-dose80.0437
GSM1296098T_lesional_pre-dose57.1431
GSM1296101U_lesional_pre-dose41.0828
GSM1296121V_lesional_pre-dose134.0645
GSM1296088W_lesional_pre-dose122.645
GSM1296082X_lesional_pre-dose112.3445
GSM1296115Y_lesional_pre-dose104.4241
GSM1296084Z_lesional_pre-dose125.7545
GSM1296072B_lesional_day8178.2749
GSM1296069L_lesional_day8152.646
GSM1296071P_lesional_day8127.1942
GSM1296070Y_lesional_day8115.3241
GSM1296073V_lesional_day8106.9242
GSM1296034A_lesional_day1595.1940
GSM1296041G_lesional_day15117.443
GSM1296035R_lesional_day1583.1940
GSM1296038U_lesional_day15113.0143
GSM1296047B_lesional_day15224.2153
GSM1296039E_lesional_day15134.3646
GSM1296042H_lesional_day15172.3648
GSM1296043L_lesional_day15135.2944
GSM1296037M_lesional_day1537.7525
GSM1296046P_lesional_day15180.8249
GSM1296044Q_lesional_day15185.5249
GSM1296045Y_lesional_day15129.543
GSM1296025C_lesional_day15127.4146
GSM1296033D_lesional_day15103.5642
GSM1296027I_lesional_day15139.3349
GSM1296032J_lesional_day1579.7338
GSM1296024K_lesional_day15110.6944
GSM1296031W_lesional_day1555.532
GSM1296028X_lesional_day15120.7545
GSM1296029Z_lesional_day15109.9843
GSM1296026F_lesional_day15102.1542
GSM1296030O_lesional_day15111.8446
GSM1296040S_lesional_day1567.0435
GSM1296036T_lesional_day15106.8141
GSM1296048V_lesional_day15109.7642
GSM1296059A_lesional_day4324.7922
GSM1296066G_lesional_day43150.9346
GSM1296060R_lesional_day4394.241
GSM1296063U_lesional_day43113.2143
GSM1296064E_lesional_day4390.6240
GSM1296067H_lesional_day4392.1338
GSM1296062M_lesional_day4349.5831
GSM1296068Q_lesional_day43185.7349
GSM1296050C_lesional_day43127.4845
GSM1296057D_lesional_day43121.9245
GSM1296052I_lesional_day4384.7141
GSM1296054J_lesional_day43171.3649
GSM1296049K_lesional_day4397.3441
GSM1296055W_lesional_day4377.0536
GSM1296053X_lesional_day43106.7743
GSM1296058Z_lesional_day4377.7339
GSM1296051F_lesional_day4394.3441
GSM1296056O_lesional_day4366.9137
GSM1296065S_lesional_day43130.5145
GSM1296061T_lesional_day4360.8333
GSM1296095A_non-lesional_pre-dose133.1547
GSM1296120B_non-lesional_pre-dose191.0450
GSM1296077C_non-lesional_pre-dose126.0746
GSM1296093D_non-lesional_pre-dose194.6551
GSM1296104E_non-lesional_pre-dose186.2751
GSM1296079F_non-lesional_pre-dose72.1337
GSM1296108G_non-lesional_pre-dose159.7248
GSM1296110H_non-lesional_pre-dose138.3644
GSM1296081I_non-lesional_pre-dose78.0339
GSM1296091J_non-lesional_pre-dose152.2249
GSM1296075K_non-lesional_pre-dose148.7549
GSM1296112L_non-lesional_pre-dose137.2843
GSM1296100M_non-lesional_pre-dose104.6441
GSM1296087O_non-lesional_pre-dose157.6551
GSM1296118P_non-lesional_pre-dose201.5851
GSM1296114Q_non-lesional_pre-dose194.0650
GSM1296097R_non-lesional_pre-dose113.6943
GSM1296106S_non-lesional_pre-dose112.8142
GSM1296102U_non-lesional_pre-dose113.2442
GSM1296122V_non-lesional_pre-dose124.3243
GSM1296089W_non-lesional_pre-dose123.1943
GSM1296083X_non-lesional_pre-dose94.0841
GSM1296116Y_non-lesional_pre-dose168.2647
GSM1296085Z_non-lesional_pre-dose194.6852