ProfileGDS5420 / 235849_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 45% 90% 68% 68% 45% 79% 81% 64% 25% 86% 70% 88% 74% 68% 75% 81% 80% 85% 18% 78% 79% 67% 60% 84% 73% 88% 93% 93% 90% 78% 66% 75% 83% 87% 80% 70% 85% 91% 86% 92% 92% 96% 71% 67% 61% 69% 63% 90% 58% 80% 64% 52% 70% 46% 88% 86% 79% 82% 92% 80% 81% 52% 93% 88% 87% 75% 69% 66% 95% 57% 96% 76% 79% 91% 42% 91% 91% 84% 66% 83% 81% 91% 92% 75% 57% 92% 96% 74% 75% 83% 91% 95% 91% 88% 85% 96% 74% 94% 69% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose125.7145
GSM1296119B_lesional_pre-dose2096.8890
GSM1296076C_lesional_pre-dose490.9368
GSM1296092D_lesional_pre-dose486.0568
GSM1296103E_lesional_pre-dose127.0845
GSM1296078F_lesional_pre-dose1037.6879
GSM1296107G_lesional_pre-dose1123.5981
GSM1296109H_lesional_pre-dose405.6264
GSM1296080I_lesional_pre-dose30.3725
GSM1296090J_lesional_pre-dose1640.3386
GSM1296074K_lesional_pre-dose532.970
GSM1296111L_lesional_pre-dose1822.9588
GSM1296099M_lesional_pre-dose744.6474
GSM1296086O_lesional_pre-dose507.1268
GSM1296117P_lesional_pre-dose748.0875
GSM1296113Q_lesional_pre-dose1116.881
GSM1296096R_lesional_pre-dose1063.3880
GSM1296105S_lesional_pre-dose1489.0985
GSM1296098T_lesional_pre-dose26.4418
GSM1296101U_lesional_pre-dose932.478
GSM1296121V_lesional_pre-dose977.3379
GSM1296088W_lesional_pre-dose494.8867
GSM1296082X_lesional_pre-dose296.2360
GSM1296115Y_lesional_pre-dose1352.8384
GSM1296084Z_lesional_pre-dose707.3173
GSM1296072B_lesional_day81841.9788
GSM1296069L_lesional_day82585.7793
GSM1296071P_lesional_day82515.5993
GSM1296070Y_lesional_day81963.9990
GSM1296073V_lesional_day8926.3578
GSM1296034A_lesional_day15476.4966
GSM1296041G_lesional_day15786.0475
GSM1296035R_lesional_day15129583
GSM1296038U_lesional_day151709.0587
GSM1296047B_lesional_day151020.4580
GSM1296039E_lesional_day15574.9170
GSM1296042H_lesional_day151402.6485
GSM1296043L_lesional_day152109.6991
GSM1296037M_lesional_day151519.1786
GSM1296046P_lesional_day152308.1892
GSM1296044Q_lesional_day152313.0992
GSM1296045Y_lesional_day153444.0496
GSM1296025C_lesional_day15604.8871
GSM1296033D_lesional_day15497.2667
GSM1296027I_lesional_day15314.6261
GSM1296032J_lesional_day15567.5269
GSM1296024K_lesional_day15380.363
GSM1296031W_lesional_day151995.8790
GSM1296028X_lesional_day15277.2958
GSM1296029Z_lesional_day151073.2380
GSM1296026F_lesional_day15381.5664
GSM1296030O_lesional_day15170.6452
GSM1296040S_lesional_day15578.9970
GSM1296036T_lesional_day15148.0446
GSM1296048V_lesional_day151869.3688
GSM1296059A_lesional_day431568.7986
GSM1296066G_lesional_day43989.2979
GSM1296060R_lesional_day431179.1282
GSM1296063U_lesional_day432663.7392
GSM1296064E_lesional_day431092.1780
GSM1296067H_lesional_day431126.3181
GSM1296062M_lesional_day43197.152
GSM1296068Q_lesional_day432508.7593
GSM1296050C_lesional_day431836.2288
GSM1296057D_lesional_day431662.8287
GSM1296052I_lesional_day43811.2175
GSM1296054J_lesional_day43554.6569
GSM1296049K_lesional_day43462.566
GSM1296055W_lesional_day433386.4795
GSM1296053X_lesional_day43265.0457
GSM1296058Z_lesional_day433690.0296
GSM1296051F_lesional_day43842.5176
GSM1296056O_lesional_day431045.479
GSM1296065S_lesional_day432231.9691
GSM1296061T_lesional_day43110.142
GSM1296095A_non-lesional_pre-dose2429.5691
GSM1296120B_non-lesional_pre-dose2269.9591
GSM1296077C_non-lesional_pre-dose1376.0984
GSM1296093D_non-lesional_pre-dose482.5966
GSM1296104E_non-lesional_pre-dose1254.0583
GSM1296079F_non-lesional_pre-dose1163.3681
GSM1296108G_non-lesional_pre-dose2384.7391
GSM1296110H_non-lesional_pre-dose2390.2192
GSM1296081I_non-lesional_pre-dose802.8975
GSM1296091J_non-lesional_pre-dose251.0857
GSM1296075K_non-lesional_pre-dose2751.3592
GSM1296112L_non-lesional_pre-dose3279.3996
GSM1296100M_non-lesional_pre-dose760.6174
GSM1296087O_non-lesional_pre-dose770.0875
GSM1296118P_non-lesional_pre-dose1239.5983
GSM1296114Q_non-lesional_pre-dose2165.2491
GSM1296097R_non-lesional_pre-dose3667.8395
GSM1296106S_non-lesional_pre-dose2266.4491
GSM1296102U_non-lesional_pre-dose1691.6588
GSM1296122V_non-lesional_pre-dose1389.1185
GSM1296089W_non-lesional_pre-dose3701.7596
GSM1296083X_non-lesional_pre-dose729.1774
GSM1296116Y_non-lesional_pre-dose2867.4694
GSM1296085Z_non-lesional_pre-dose532.8869