ProfileGDS5420 / 236841_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 67% 72% 61% 49% 75% 51% 75% 83% 62% 48% 63% 75% 64% 57% 77% 78% 67% 67% 75% 69% 74% 59% 51% 75% 57% 71% 78% 79% 75% 71% 69% 76% 66% 64% 73% 59% 72% 76% 62% 80% 79% 75% 66% 49% 55% 55% 64% 62% 53% 57% 55% 52% 69% 77% 72% 66% 77% 63% 64% 66% 70% 65% 76% 64% 54% 56% 61% 62% 63% 59% 61% 55% 60% 60% 73% 62% 74% 67% 58% 66% 62% 75% 80% 48% 52% 63% 77% 60% 43% 81% 79% 66% 64% 66% 69% 64% 62% 81% 50% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose485.8167
GSM1296119B_lesional_pre-dose651.4972
GSM1296076C_lesional_pre-dose302.6361
GSM1296092D_lesional_pre-dose145.1149
GSM1296103E_lesional_pre-dose790.4175
GSM1296078F_lesional_pre-dose166.9151
GSM1296107G_lesional_pre-dose755.8375
GSM1296109H_lesional_pre-dose1252.4583
GSM1296080I_lesional_pre-dose339.2162
GSM1296090J_lesional_pre-dose141.4948
GSM1296074K_lesional_pre-dose349.3363
GSM1296111L_lesional_pre-dose752.3575
GSM1296099M_lesional_pre-dose423.1464
GSM1296086O_lesional_pre-dose244.957
GSM1296117P_lesional_pre-dose872.7477
GSM1296113Q_lesional_pre-dose905.678
GSM1296096R_lesional_pre-dose489.1567
GSM1296105S_lesional_pre-dose479.7967
GSM1296098T_lesional_pre-dose784.8675
GSM1296101U_lesional_pre-dose564.9269
GSM1296121V_lesional_pre-dose712.2974
GSM1296088W_lesional_pre-dose300.2359
GSM1296082X_lesional_pre-dose163.0951
GSM1296115Y_lesional_pre-dose758.0975
GSM1296084Z_lesional_pre-dose267.7957
GSM1296072B_lesional_day8605.9571
GSM1296069L_lesional_day8929.9878
GSM1296071P_lesional_day8964.9279
GSM1296070Y_lesional_day8774.2475
GSM1296073V_lesional_day8594.2371
GSM1296034A_lesional_day15582.4369
GSM1296041G_lesional_day15837.5276
GSM1296035R_lesional_day15466.2466
GSM1296038U_lesional_day15407.7564
GSM1296047B_lesional_day1567673
GSM1296039E_lesional_day15287.0259
GSM1296042H_lesional_day15630.2372
GSM1296043L_lesional_day15798.8776
GSM1296037M_lesional_day15376.0562
GSM1296046P_lesional_day151053.180
GSM1296044Q_lesional_day15960.6379
GSM1296045Y_lesional_day15752.9575
GSM1296025C_lesional_day15457.5266
GSM1296033D_lesional_day15164.5349
GSM1296027I_lesional_day15213.4655
GSM1296032J_lesional_day15236.8655
GSM1296024K_lesional_day15387.0464
GSM1296031W_lesional_day15373.7362
GSM1296028X_lesional_day15207.9353
GSM1296029Z_lesional_day15273.9557
GSM1296026F_lesional_day15225.5655
GSM1296030O_lesional_day15176.9752
GSM1296040S_lesional_day15546.9169
GSM1296036T_lesional_day15897.3277
GSM1296048V_lesional_day15623.5972
GSM1296059A_lesional_day43450.4266
GSM1296066G_lesional_day43878.6377
GSM1296060R_lesional_day43395.6363
GSM1296063U_lesional_day43399.4564
GSM1296064E_lesional_day43446.8366
GSM1296067H_lesional_day43585.2670
GSM1296062M_lesional_day43429.4765
GSM1296068Q_lesional_day43821.2976
GSM1296050C_lesional_day43385.7264
GSM1296057D_lesional_day43228.5954
GSM1296052I_lesional_day43232.3956
GSM1296054J_lesional_day43355.4361
GSM1296049K_lesional_day43356.5262
GSM1296055W_lesional_day43398.5363
GSM1296053X_lesional_day43309.1459
GSM1296058Z_lesional_day43329.9161
GSM1296051F_lesional_day43224.855
GSM1296056O_lesional_day43302.1460
GSM1296065S_lesional_day43322.2660
GSM1296061T_lesional_day43707.4173
GSM1296095A_non-lesional_pre-dose360.4862
GSM1296120B_non-lesional_pre-dose742.8274
GSM1296077C_non-lesional_pre-dose467.7967
GSM1296093D_non-lesional_pre-dose295.4658
GSM1296104E_non-lesional_pre-dose438.9966
GSM1296079F_non-lesional_pre-dose343.7562
GSM1296108G_non-lesional_pre-dose750.1275
GSM1296110H_non-lesional_pre-dose1029.1780
GSM1296081I_non-lesional_pre-dose139.2548
GSM1296091J_non-lesional_pre-dose183.7752
GSM1296075K_non-lesional_pre-dose357.9563
GSM1296112L_non-lesional_pre-dose843.3177
GSM1296100M_non-lesional_pre-dose335.160
GSM1296087O_non-lesional_pre-dose97.6443
GSM1296118P_non-lesional_pre-dose1077.9581
GSM1296114Q_non-lesional_pre-dose970.8279
GSM1296097R_non-lesional_pre-dose447.2766
GSM1296106S_non-lesional_pre-dose424.7364
GSM1296102U_non-lesional_pre-dose479.8666
GSM1296122V_non-lesional_pre-dose555.0569
GSM1296089W_non-lesional_pre-dose414.864
GSM1296083X_non-lesional_pre-dose366.0662
GSM1296116Y_non-lesional_pre-dose1060.5881
GSM1296085Z_non-lesional_pre-dose172.5150