ProfileGDS5420 / 238240_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 47% 37% 33% 39% 44% 43% 47% 43% 40% 40% 37% 47% 47% 35% 55% 50% 47% 45% 48% 45% 33% 32% 40% 51% 30% 43% 53% 51% 55% 45% 47% 49% 43% 47% 42% 44% 49% 53% 46% 52% 50% 53% 27% 37% 35% 31% 30% 30% 32% 35% 31% 33% 52% 44% 45% 48% 50% 40% 52% 51% 42% 40% 48% 27% 26% 31% 25% 27% 37% 27% 43% 32% 37% 45% 44% 54% 37% 28% 30% 46% 12% 47% 45% 39% 39% 42% 50% 44% 37% 46% 51% 45% 51% 42% 33% 39% 31% 51% 32% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose146.4547
GSM1296119B_lesional_pre-dose82.5437
GSM1296076C_lesional_pre-dose56.6433
GSM1296092D_lesional_pre-dose71.3939
GSM1296103E_lesional_pre-dose112.6744
GSM1296078F_lesional_pre-dose101.4143
GSM1296107G_lesional_pre-dose150.1247
GSM1296109H_lesional_pre-dose124.8343
GSM1296080I_lesional_pre-dose83.1240
GSM1296090J_lesional_pre-dose84.9840
GSM1296074K_lesional_pre-dose63.237
GSM1296111L_lesional_pre-dose156.8247
GSM1296099M_lesional_pre-dose148.447
GSM1296086O_lesional_pre-dose60.4535
GSM1296117P_lesional_pre-dose251.0955
GSM1296113Q_lesional_pre-dose193.2850
GSM1296096R_lesional_pre-dose142.6347
GSM1296105S_lesional_pre-dose130.9245
GSM1296098T_lesional_pre-dose156.448
GSM1296101U_lesional_pre-dose131.2845
GSM1296121V_lesional_pre-dose62.3433
GSM1296088W_lesional_pre-dose50.4832
GSM1296082X_lesional_pre-dose80.4440
GSM1296115Y_lesional_pre-dose192.6951
GSM1296084Z_lesional_pre-dose48.8230
GSM1296072B_lesional_day8118.8743
GSM1296069L_lesional_day8226.1453
GSM1296071P_lesional_day8212.1151
GSM1296070Y_lesional_day8256.355
GSM1296073V_lesional_day8125.1945
GSM1296034A_lesional_day15155.4447
GSM1296041G_lesional_day15170.1149
GSM1296035R_lesional_day15105.643
GSM1296038U_lesional_day15146.8347
GSM1296047B_lesional_day15119.6542
GSM1296039E_lesional_day15116.9444
GSM1296042H_lesional_day15174.4649
GSM1296043L_lesional_day15232.8253
GSM1296037M_lesional_day15143.3746
GSM1296046P_lesional_day15213.6852
GSM1296044Q_lesional_day15194.6950
GSM1296045Y_lesional_day15226.3453
GSM1296025C_lesional_day1538.4727
GSM1296033D_lesional_day1573.7537
GSM1296027I_lesional_day1555.1535
GSM1296032J_lesional_day1550.9531
GSM1296024K_lesional_day1543.3730
GSM1296031W_lesional_day1549.1130
GSM1296028X_lesional_day1553.5432
GSM1296029Z_lesional_day1564.3835
GSM1296026F_lesional_day1552.3231
GSM1296030O_lesional_day1545.0733
GSM1296040S_lesional_day15197.0552
GSM1296036T_lesional_day15128.3244
GSM1296048V_lesional_day15135.845
GSM1296059A_lesional_day43150.2348
GSM1296066G_lesional_day43190.8750
GSM1296060R_lesional_day4387.840
GSM1296063U_lesional_day43201.4652
GSM1296064E_lesional_day43179.3751
GSM1296067H_lesional_day43124.3342
GSM1296062M_lesional_day4392.1840
GSM1296068Q_lesional_day43179.748
GSM1296050C_lesional_day4341.4727
GSM1296057D_lesional_day4333.6126
GSM1296052I_lesional_day4343.6231
GSM1296054J_lesional_day4334.7325
GSM1296049K_lesional_day4337.227
GSM1296055W_lesional_day4378.0637
GSM1296053X_lesional_day4337.3927
GSM1296058Z_lesional_day43103.5443
GSM1296051F_lesional_day4354.9532
GSM1296056O_lesional_day4367.0537
GSM1296065S_lesional_day43125.7345
GSM1296061T_lesional_day43126.7644
GSM1296095A_non-lesional_pre-dose215.8154
GSM1296120B_non-lesional_pre-dose89.9237
GSM1296077C_non-lesional_pre-dose39.1228
GSM1296093D_non-lesional_pre-dose48.4930
GSM1296104E_non-lesional_pre-dose136.3146
GSM1296079F_non-lesional_pre-dose13.9212
GSM1296108G_non-lesional_pre-dose155.3847
GSM1296110H_non-lesional_pre-dose145.1345
GSM1296081I_non-lesional_pre-dose73.4339
GSM1296091J_non-lesional_pre-dose81.0539
GSM1296075K_non-lesional_pre-dose96.142
GSM1296112L_non-lesional_pre-dose203.7750
GSM1296100M_non-lesional_pre-dose126.0144
GSM1296087O_non-lesional_pre-dose62.2437
GSM1296118P_non-lesional_pre-dose157.3146
GSM1296114Q_non-lesional_pre-dose197.4751
GSM1296097R_non-lesional_pre-dose123.7545
GSM1296106S_non-lesional_pre-dose198.251
GSM1296102U_non-lesional_pre-dose116.7242
GSM1296122V_non-lesional_pre-dose68.9433
GSM1296089W_non-lesional_pre-dose94.2339
GSM1296083X_non-lesional_pre-dose49.8731
GSM1296116Y_non-lesional_pre-dose214.1851
GSM1296085Z_non-lesional_pre-dose54.1932