ProfileGDS5420 / 238488_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 49% 66% 63% 66% 57% 63% 66% 65% 61% 62% 62% 61% 66% 61% 65% 54% 64% 76% 54% 61% 67% 70% 54% 59% 62% 70% 69% 74% 67% 62% 69% 55% 58% 68% 74% 65% 71% 71% 69% 69% 62% 65% 82% 72% 70% 64% 77% 75% 65% 78% 75% 57% 64% 59% 70% 58% 64% 67% 65% 56% 81% 68% 70% 81% 81% 74% 68% 79% 76% 74% 67% 72% 62% 72% 67% 60% 68% 78% 75% 59% 80% 70% 74% 72% 59% 69% 71% 67% 66% 72% 59% 68% 75% 67% 80% 71% 70% 68% 65% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose158.4449
GSM1296119B_lesional_pre-dose44266
GSM1296076C_lesional_pre-dose360.8363
GSM1296092D_lesional_pre-dose448.5166
GSM1296103E_lesional_pre-dose256.3557
GSM1296078F_lesional_pre-dose338.3163
GSM1296107G_lesional_pre-dose454.266
GSM1296109H_lesional_pre-dose437.2965
GSM1296080I_lesional_pre-dose328.5861
GSM1296090J_lesional_pre-dose331.4962
GSM1296074K_lesional_pre-dose327.2862
GSM1296111L_lesional_pre-dose346.1761
GSM1296099M_lesional_pre-dose468.2266
GSM1296086O_lesional_pre-dose317.7161
GSM1296117P_lesional_pre-dose421.7365
GSM1296113Q_lesional_pre-dose243.8454
GSM1296096R_lesional_pre-dose395.0864
GSM1296105S_lesional_pre-dose821.6376
GSM1296098T_lesional_pre-dose229.3754
GSM1296101U_lesional_pre-dose354.6261
GSM1296121V_lesional_pre-dose476.6267
GSM1296088W_lesional_pre-dose579.8870
GSM1296082X_lesional_pre-dose196.1154
GSM1296115Y_lesional_pre-dose308.8959
GSM1296084Z_lesional_pre-dose347.6162
GSM1296072B_lesional_day8566.9570
GSM1296069L_lesional_day8556.2669
GSM1296071P_lesional_day8731.0574
GSM1296070Y_lesional_day8482.267
GSM1296073V_lesional_day8342.3362
GSM1296034A_lesional_day1557969
GSM1296041G_lesional_day15238.6655
GSM1296035R_lesional_day15277.4258
GSM1296038U_lesional_day15495.168
GSM1296047B_lesional_day15728.7374
GSM1296039E_lesional_day15425.1565
GSM1296042H_lesional_day15605.0371
GSM1296043L_lesional_day15612.1171
GSM1296037M_lesional_day15546.1369
GSM1296046P_lesional_day15565.0469
GSM1296044Q_lesional_day15371.862
GSM1296045Y_lesional_day15428.3665
GSM1296025C_lesional_day151237.1982
GSM1296033D_lesional_day15646.7172
GSM1296027I_lesional_day15558.6870
GSM1296032J_lesional_day15419.9264
GSM1296024K_lesional_day15890.2377
GSM1296031W_lesional_day15784.1175
GSM1296028X_lesional_day15422.865
GSM1296029Z_lesional_day15927.3478
GSM1296026F_lesional_day15790.8875
GSM1296030O_lesional_day15239.3357
GSM1296040S_lesional_day15408.2764
GSM1296036T_lesional_day15314.8959
GSM1296048V_lesional_day15581.6370
GSM1296059A_lesional_day43274.0858
GSM1296066G_lesional_day43401.5564
GSM1296060R_lesional_day43480.9567
GSM1296063U_lesional_day43411.965
GSM1296064E_lesional_day43235.5156
GSM1296067H_lesional_day431120.2381
GSM1296062M_lesional_day43524.1568
GSM1296068Q_lesional_day43572.6770
GSM1296050C_lesional_day431115.2781
GSM1296057D_lesional_day431138.6981
GSM1296052I_lesional_day43743.0374
GSM1296054J_lesional_day43517.9568
GSM1296049K_lesional_day431015.0179
GSM1296055W_lesional_day43825.1576
GSM1296053X_lesional_day43737.0474
GSM1296058Z_lesional_day43485.1367
GSM1296051F_lesional_day43622.6172
GSM1296056O_lesional_day43344.2462
GSM1296065S_lesional_day43633.4572
GSM1296061T_lesional_day43508.167
GSM1296095A_non-lesional_pre-dose306.8860
GSM1296120B_non-lesional_pre-dose498.468
GSM1296077C_non-lesional_pre-dose939.8978
GSM1296093D_non-lesional_pre-dose811.4775
GSM1296104E_non-lesional_pre-dose291.459
GSM1296079F_non-lesional_pre-dose1078.2380
GSM1296108G_non-lesional_pre-dose561.3470
GSM1296110H_non-lesional_pre-dose728.7274
GSM1296081I_non-lesional_pre-dose656.6172
GSM1296091J_non-lesional_pre-dose287.1959
GSM1296075K_non-lesional_pre-dose526.6569
GSM1296112L_non-lesional_pre-dose615.8771
GSM1296100M_non-lesional_pre-dose506.2167
GSM1296087O_non-lesional_pre-dose426.1966
GSM1296118P_non-lesional_pre-dose639.9672
GSM1296114Q_non-lesional_pre-dose319.0259
GSM1296097R_non-lesional_pre-dose512.2568
GSM1296106S_non-lesional_pre-dose791.2275
GSM1296102U_non-lesional_pre-dose511.7467
GSM1296122V_non-lesional_pre-dose1023.5580
GSM1296089W_non-lesional_pre-dose628.1171
GSM1296083X_non-lesional_pre-dose602.7170
GSM1296116Y_non-lesional_pre-dose523.3268
GSM1296085Z_non-lesional_pre-dose420.7665