ProfileGDS5420 / 239174_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 31% 12% 20% 32% 30% 11% 20% 26% 39% 27% 31% 17% 25% 26% 25% 29% 17% 27% 36% 42% 27% 15% 23% 27% 32% 24% 20% 26% 19% 28% 27% 11% 19% 15% 14% 16% 8% 22% 21% 25% 30% 38% 28% 28% 39% 35% 34% 34% 25% 23% 37% 15% 38% 27% 26% 6% 28% 29% 22% 32% 23% 29% 33% 25% 40% 38% 30% 25% 33% 28% 32% 28% 44% 16% 28% 28% 39% 36% 21% 15% 15% 24% 23% 18% 21% 37% 25% 32% 28% 29% 23% 42% 30% 26% 26% 29% 42% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose47.6931
GSM1296119B_lesional_pre-dose14.1112
GSM1296076C_lesional_pre-dose25.7120
GSM1296092D_lesional_pre-dose45.8832
GSM1296103E_lesional_pre-dose44.4930
GSM1296078F_lesional_pre-dose11.8511
GSM1296107G_lesional_pre-dose28.2420
GSM1296109H_lesional_pre-dose42.5326
GSM1296080I_lesional_pre-dose79.6539
GSM1296090J_lesional_pre-dose34.7227
GSM1296074K_lesional_pre-dose43.1831
GSM1296111L_lesional_pre-dose24.6517
GSM1296099M_lesional_pre-dose34.1125
GSM1296086O_lesional_pre-dose34.4926
GSM1296117P_lesional_pre-dose40.9925
GSM1296113Q_lesional_pre-dose60.2129
GSM1296096R_lesional_pre-dose17.0117
GSM1296105S_lesional_pre-dose39.0127
GSM1296098T_lesional_pre-dose74.6736
GSM1296101U_lesional_pre-dose109.5242
GSM1296121V_lesional_pre-dose42.9627
GSM1296088W_lesional_pre-dose14.8215
GSM1296082X_lesional_pre-dose27.0323
GSM1296115Y_lesional_pre-dose42.6427
GSM1296084Z_lesional_pre-dose55.5732
GSM1296072B_lesional_day835.2724
GSM1296069L_lesional_day830.9420
GSM1296071P_lesional_day847.1226
GSM1296070Y_lesional_day827.4819
GSM1296073V_lesional_day845.4628
GSM1296034A_lesional_day1540.4527
GSM1296041G_lesional_day1512.511
GSM1296035R_lesional_day1518.7619
GSM1296038U_lesional_day1515.5515
GSM1296047B_lesional_day1518.2614
GSM1296039E_lesional_day15
GSM1296042H_lesional_day1521.8416
GSM1296043L_lesional_day1510.238
GSM1296037M_lesional_day1530.2522
GSM1296046P_lesional_day1533.6221
GSM1296044Q_lesional_day1541.1925
GSM1296045Y_lesional_day1561.6830
GSM1296025C_lesional_day1580.2438
GSM1296033D_lesional_day1540.428
GSM1296027I_lesional_day1533.1428
GSM1296032J_lesional_day1584.7339
GSM1296024K_lesional_day1560.0735
GSM1296031W_lesional_day1564.1834
GSM1296028X_lesional_day1559.2634
GSM1296029Z_lesional_day1531.1125
GSM1296026F_lesional_day1529.9223
GSM1296030O_lesional_day1562.4837
GSM1296040S_lesional_day1517.5915
GSM1296036T_lesional_day1586.4738
GSM1296048V_lesional_day1544.6427
GSM1296059A_lesional_day4332.7826
GSM1296066G_lesional_day436.996
GSM1296060R_lesional_day4338.8428
GSM1296063U_lesional_day4345.1929
GSM1296064E_lesional_day4326.7422
GSM1296067H_lesional_day43
GSM1296062M_lesional_day4354.3532
GSM1296068Q_lesional_day4340.3623
GSM1296050C_lesional_day4348.3729
GSM1296057D_lesional_day4354.8833
GSM1296052I_lesional_day4329.5925
GSM1296054J_lesional_day4392.240
GSM1296049K_lesional_day4376.7838
GSM1296055W_lesional_day4349.9330
GSM1296053X_lesional_day4333.6725
GSM1296058Z_lesional_day4352.0133
GSM1296051F_lesional_day4341.0428
GSM1296056O_lesional_day4347.5932
GSM1296065S_lesional_day4340.3428
GSM1296061T_lesional_day43121.5144
GSM1296095A_non-lesional_pre-dose16.9116
GSM1296120B_non-lesional_pre-dose50.6128
GSM1296077C_non-lesional_pre-dose38.6528
GSM1296093D_non-lesional_pre-dose93.8739
GSM1296104E_non-lesional_pre-dose7136
GSM1296079F_non-lesional_pre-dose25.9921
GSM1296108G_non-lesional_pre-dose17.3715
GSM1296110H_non-lesional_pre-dose20.715
GSM1296081I_non-lesional_pre-dose26.5824
GSM1296091J_non-lesional_pre-dose27.5123
GSM1296075K_non-lesional_pre-dose20.4118
GSM1296112L_non-lesional_pre-dose35.8421
GSM1296100M_non-lesional_pre-dose81.4537
GSM1296087O_non-lesional_pre-dose29.3825
GSM1296118P_non-lesional_pre-dose66.7432
GSM1296114Q_non-lesional_pre-dose52.6428
GSM1296097R_non-lesional_pre-dose43.9929
GSM1296106S_non-lesional_pre-dose31.6423
GSM1296102U_non-lesional_pre-dose116.2742
GSM1296122V_non-lesional_pre-dose55.3630
GSM1296089W_non-lesional_pre-dose39.8626
GSM1296083X_non-lesional_pre-dose35.6726
GSM1296116Y_non-lesional_pre-dose60.4829
GSM1296085Z_non-lesional_pre-dose106.8742