ProfileGDS5420 / 244377_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 62% 56% 60% 63% 60% 60% 58% 56% 63% 59% 61% 56% 56% 60% 54% 59% 58% 56% 76% 71% 59% 62% 58% 57% 69% 62% 64% 56% 62% 61% 72% 58% 59% 63% 64% 67% 60% 60% 64% 64% 66% 65% 72% 68% 66% 71% 73% 70% 70% 71% 62% 66% 62% 71% 64% 58% 58% 65% 62% 62% 59% 66% 62% 63% 68% 66% 75% 68% 66% 72% 67% 59% 69% 57% 70% 63% 63% 70% 78% 65% 65% 69% 61% 68% 63% 68% 59% 76% 71% 60% 64% 67% 66% 77% 60% 73% 70% 61% 73% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose358.3662
GSM1296119B_lesional_pre-dose250.5856
GSM1296076C_lesional_pre-dose283.7460
GSM1296092D_lesional_pre-dose350.4363
GSM1296103E_lesional_pre-dose312.3860
GSM1296078F_lesional_pre-dose286.3460
GSM1296107G_lesional_pre-dose287.4658
GSM1296109H_lesional_pre-dose269.9856
GSM1296080I_lesional_pre-dose374.5763
GSM1296090J_lesional_pre-dose276.6959
GSM1296074K_lesional_pre-dose301.2161
GSM1296111L_lesional_pre-dose265.2256
GSM1296099M_lesional_pre-dose248.7656
GSM1296086O_lesional_pre-dose298.1560
GSM1296117P_lesional_pre-dose226.8854
GSM1296113Q_lesional_pre-dose309.1659
GSM1296096R_lesional_pre-dose285.4958
GSM1296105S_lesional_pre-dose258.3156
GSM1296098T_lesional_pre-dose812.776
GSM1296101U_lesional_pre-dose625.7671
GSM1296121V_lesional_pre-dose309.3759
GSM1296088W_lesional_pre-dose353.962
GSM1296082X_lesional_pre-dose252.6958
GSM1296115Y_lesional_pre-dose26457
GSM1296084Z_lesional_pre-dose541.1569
GSM1296072B_lesional_day8356.8262
GSM1296069L_lesional_day8425.8764
GSM1296071P_lesional_day8274.5356
GSM1296070Y_lesional_day8376.9762
GSM1296073V_lesional_day8325.6761
GSM1296034A_lesional_day15676.6372
GSM1296041G_lesional_day15285.3858
GSM1296035R_lesional_day15307.4859
GSM1296038U_lesional_day15372.9363
GSM1296047B_lesional_day15400.6264
GSM1296039E_lesional_day15452.8267
GSM1296042H_lesional_day15329.5760
GSM1296043L_lesional_day15331.2660
GSM1296037M_lesional_day15415.8364
GSM1296046P_lesional_day15407.2464
GSM1296044Q_lesional_day15474.6966
GSM1296045Y_lesional_day15431.3565
GSM1296025C_lesional_day15633.1972
GSM1296033D_lesional_day15517.4968
GSM1296027I_lesional_day15429.1466
GSM1296032J_lesional_day15628.3771
GSM1296024K_lesional_day15674.9973
GSM1296031W_lesional_day15594.7670
GSM1296028X_lesional_day15575.2670
GSM1296029Z_lesional_day15625.6871
GSM1296026F_lesional_day15342.862
GSM1296030O_lesional_day15436.9666
GSM1296040S_lesional_day15362.7262
GSM1296036T_lesional_day15629.6771
GSM1296048V_lesional_day15404.0764
GSM1296059A_lesional_day43273.0558
GSM1296066G_lesional_day43284.0958
GSM1296060R_lesional_day43439.7565
GSM1296063U_lesional_day43351.0462
GSM1296064E_lesional_day43338.5662
GSM1296067H_lesional_day43332.3859
GSM1296062M_lesional_day43462.2566
GSM1296068Q_lesional_day43378.0262
GSM1296050C_lesional_day43371.6963
GSM1296057D_lesional_day43511.0968
GSM1296052I_lesional_day43450.0166
GSM1296054J_lesional_day43798.4675
GSM1296049K_lesional_day43516.6768
GSM1296055W_lesional_day43456.9466
GSM1296053X_lesional_day43668.1972
GSM1296058Z_lesional_day43496.667
GSM1296051F_lesional_day43283.0459
GSM1296056O_lesional_day43545.469
GSM1296065S_lesional_day43275.9957
GSM1296061T_lesional_day43587.970
GSM1296095A_non-lesional_pre-dose368.5963
GSM1296120B_non-lesional_pre-dose376.9563
GSM1296077C_non-lesional_pre-dose551.7170
GSM1296093D_non-lesional_pre-dose918.7178
GSM1296104E_non-lesional_pre-dose414.9165
GSM1296079F_non-lesional_pre-dose421.5965
GSM1296108G_non-lesional_pre-dose529.669
GSM1296110H_non-lesional_pre-dose355.5261
GSM1296081I_non-lesional_pre-dose505.5868
GSM1296091J_non-lesional_pre-dose374.7563
GSM1296075K_non-lesional_pre-dose475.468
GSM1296112L_non-lesional_pre-dose330.1759
GSM1296100M_non-lesional_pre-dose815.6776
GSM1296087O_non-lesional_pre-dose594.0471
GSM1296118P_non-lesional_pre-dose341.5160
GSM1296114Q_non-lesional_pre-dose423.4564
GSM1296097R_non-lesional_pre-dose468.2567
GSM1296106S_non-lesional_pre-dose468.1966
GSM1296102U_non-lesional_pre-dose878.6177
GSM1296122V_non-lesional_pre-dose324.1160
GSM1296089W_non-lesional_pre-dose685.3173
GSM1296083X_non-lesional_pre-dose574.4170
GSM1296116Y_non-lesional_pre-dose358.9761
GSM1296085Z_non-lesional_pre-dose684.1773