ProfileGDS5420 / 244790_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 59% 48% 48% 54% 50% 51% 47% 50% 62% 49% 52% 43% 53% 54% 50% 47% 55% 53% 57% 48% 47% 51% 48% 47% 51% 48% 45% 47% 47% 48% 57% 48% 54% 54% 49% 46% 51% 47% 48% 50% 49% 49% 63% 55% 60% 58% 67% 51% 54% 54% 49% 56% 56% 59% 47% 49% 51% 55% 50% 49% 51% 56% 46% 56% 48% 58% 61% 63% 45% 55% 47% 56% 50% 48% 63% 49% 48% 58% 57% 21% 62% 48% 51% 53% 55% 54% 45% 46% 58% 49% 43% 53% 49% 55% 45% 48% 52% 50% 49% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose299.7259
GSM1296119B_lesional_pre-dose163.0348
GSM1296076C_lesional_pre-dose135.8748
GSM1296092D_lesional_pre-dose201.6154
GSM1296103E_lesional_pre-dose173.0450
GSM1296078F_lesional_pre-dose168.3251
GSM1296107G_lesional_pre-dose154.8647
GSM1296109H_lesional_pre-dose186.6350
GSM1296080I_lesional_pre-dose358.8862
GSM1296090J_lesional_pre-dose146.7649
GSM1296074K_lesional_pre-dose171.9952
GSM1296111L_lesional_pre-dose122.2843
GSM1296099M_lesional_pre-dose208.4953
GSM1296086O_lesional_pre-dose205.1854
GSM1296117P_lesional_pre-dose185.1350
GSM1296113Q_lesional_pre-dose169.5247
GSM1296096R_lesional_pre-dose231.455
GSM1296105S_lesional_pre-dose225.8753
GSM1296098T_lesional_pre-dose273.157
GSM1296101U_lesional_pre-dose156.8548
GSM1296121V_lesional_pre-dose152.9647
GSM1296088W_lesional_pre-dose180.5851
GSM1296082X_lesional_pre-dose137.8848
GSM1296115Y_lesional_pre-dose153.8947
GSM1296084Z_lesional_pre-dose186.0251
GSM1296072B_lesional_day8165.3148
GSM1296069L_lesional_day8151.945
GSM1296071P_lesional_day8169.2147
GSM1296070Y_lesional_day8162.9747
GSM1296073V_lesional_day8153.9948
GSM1296034A_lesional_day15277.3957
GSM1296041G_lesional_day15162.7548
GSM1296035R_lesional_day15214.4954
GSM1296038U_lesional_day15220.4454
GSM1296047B_lesional_day15177.9449
GSM1296039E_lesional_day15134.0946
GSM1296042H_lesional_day15194.1951
GSM1296043L_lesional_day15160.4547
GSM1296037M_lesional_day15165.1248
GSM1296046P_lesional_day15192.7150
GSM1296044Q_lesional_day15186.7149
GSM1296045Y_lesional_day15182.8149
GSM1296025C_lesional_day15381.8863
GSM1296033D_lesional_day15235.4755
GSM1296027I_lesional_day15292.9760
GSM1296032J_lesional_day15293.3758
GSM1296024K_lesional_day15489.5467
GSM1296031W_lesional_day15190.6951
GSM1296028X_lesional_day15217.554
GSM1296029Z_lesional_day15227.6854
GSM1296026F_lesional_day15155.3549
GSM1296030O_lesional_day15227.0256
GSM1296040S_lesional_day15252.0756
GSM1296036T_lesional_day15311.4359
GSM1296048V_lesional_day15152.9347
GSM1296059A_lesional_day43155.9649
GSM1296066G_lesional_day43194.7551
GSM1296060R_lesional_day43236.1455
GSM1296063U_lesional_day43173.5250
GSM1296064E_lesional_day43150.8449
GSM1296067H_lesional_day43210.2251
GSM1296062M_lesional_day43252.1456
GSM1296068Q_lesional_day43163.6946
GSM1296050C_lesional_day43249.2456
GSM1296057D_lesional_day43154.0248
GSM1296052I_lesional_day43263.1458
GSM1296054J_lesional_day43358.7961
GSM1296049K_lesional_day43375.7163
GSM1296055W_lesional_day43134.8145
GSM1296053X_lesional_day43234.4155
GSM1296058Z_lesional_day43133.5447
GSM1296051F_lesional_day43235.5556
GSM1296056O_lesional_day43162.3650
GSM1296065S_lesional_day43161.0648
GSM1296061T_lesional_day43383.8463
GSM1296095A_non-lesional_pre-dose159.2449
GSM1296120B_non-lesional_pre-dose167.3148
GSM1296077C_non-lesional_pre-dose278.4758
GSM1296093D_non-lesional_pre-dose286.7857
GSM1296104E_non-lesional_pre-dose26.9321
GSM1296079F_non-lesional_pre-dose348.9762
GSM1296108G_non-lesional_pre-dose165.7548
GSM1296110H_non-lesional_pre-dose208.1551
GSM1296081I_non-lesional_pre-dose197.6553
GSM1296091J_non-lesional_pre-dose232.4755
GSM1296075K_non-lesional_pre-dose199.7254
GSM1296112L_non-lesional_pre-dose153.5145
GSM1296100M_non-lesional_pre-dose144.4546
GSM1296087O_non-lesional_pre-dose249.9458
GSM1296118P_non-lesional_pre-dose182.3449
GSM1296114Q_non-lesional_pre-dose128.5743
GSM1296097R_non-lesional_pre-dose210.0853
GSM1296106S_non-lesional_pre-dose174.3149
GSM1296102U_non-lesional_pre-dose257.3455
GSM1296122V_non-lesional_pre-dose137.2245
GSM1296089W_non-lesional_pre-dose158.5648
GSM1296083X_non-lesional_pre-dose198.5152
GSM1296116Y_non-lesional_pre-dose198.8650
GSM1296085Z_non-lesional_pre-dose160.9849