ProfileGDS5420 / 58994_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 75% 49% 51% 63% 76% 57% 59% 69% 69% 59% 54% 54% 67% 63% 57% 57% 69% 69% 75% 69% 54% 64% 61% 57% 66% 53% 49% 55% 54% 53% 76% 56% 70% 62% 52% 59% 55% 57% 69% 51% 52% 53% 58% 62% 59% 61% 58% 58% 62% 63% 61% 62% 76% 71% 52% 74% 56% 66% 55% 61% 58% 73% 51% 52% 64% 59% 64% 55% 57% 64% 68% 55% 68% 63% 75% 65% 47% 56% 64% 60% 60% 56% 57% 61% 61% 51% 55% 70% 60% 55% 51% 63% 65% 65% 48% 61% 69% 52% 62% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose793.3375
GSM1296119B_lesional_pre-dose166.749
GSM1296076C_lesional_pre-dose167.6451
GSM1296092D_lesional_pre-dose349.7863
GSM1296103E_lesional_pre-dose841.0576
GSM1296078F_lesional_pre-dose235.0757
GSM1296107G_lesional_pre-dose294.4859
GSM1296109H_lesional_pre-dose548.769
GSM1296080I_lesional_pre-dose555.1869
GSM1296090J_lesional_pre-dose279.0259
GSM1296074K_lesional_pre-dose197.0254
GSM1296111L_lesional_pre-dose236.3654
GSM1296099M_lesional_pre-dose493.7267
GSM1296086O_lesional_pre-dose358.6463
GSM1296117P_lesional_pre-dose274.4457
GSM1296113Q_lesional_pre-dose276.4457
GSM1296096R_lesional_pre-dose550.6769
GSM1296105S_lesional_pre-dose547.3769
GSM1296098T_lesional_pre-dose792.2675
GSM1296101U_lesional_pre-dose552.1669
GSM1296121V_lesional_pre-dose221.0254
GSM1296088W_lesional_pre-dose387.0164
GSM1296082X_lesional_pre-dose315.6261
GSM1296115Y_lesional_pre-dose266.9957
GSM1296084Z_lesional_pre-dose440.7466
GSM1296072B_lesional_day8213.3153
GSM1296069L_lesional_day8180.8449
GSM1296071P_lesional_day8266.7355
GSM1296070Y_lesional_day8244.9154
GSM1296073V_lesional_day8201.553
GSM1296034A_lesional_day15820.0776
GSM1296041G_lesional_day15256.1456
GSM1296035R_lesional_day15596.9770
GSM1296038U_lesional_day15363.462
GSM1296047B_lesional_day15214.9252
GSM1296039E_lesional_day15288.0459
GSM1296042H_lesional_day15250.0555
GSM1296043L_lesional_day15291.2457
GSM1296037M_lesional_day15557.1469
GSM1296046P_lesional_day15206.1151
GSM1296044Q_lesional_day15220.9652
GSM1296045Y_lesional_day15235.853
GSM1296025C_lesional_day15279.6258
GSM1296033D_lesional_day15357.8162
GSM1296027I_lesional_day15289.6459
GSM1296032J_lesional_day15351.8461
GSM1296024K_lesional_day15268.5158
GSM1296031W_lesional_day15300.1458
GSM1296028X_lesional_day15369.6762
GSM1296029Z_lesional_day15371.5863
GSM1296026F_lesional_day15319.6861
GSM1296030O_lesional_day15348.0262
GSM1296040S_lesional_day15836.0676
GSM1296036T_lesional_day15634.5771
GSM1296048V_lesional_day15200.5252
GSM1296059A_lesional_day43718.7674
GSM1296066G_lesional_day43265.4156
GSM1296060R_lesional_day43453.5966
GSM1296063U_lesional_day43235.6655
GSM1296064E_lesional_day43328.361
GSM1296067H_lesional_day43305.0358
GSM1296062M_lesional_day43707.8373
GSM1296068Q_lesional_day4321451
GSM1296050C_lesional_day43192.5452
GSM1296057D_lesional_day43403.8464
GSM1296052I_lesional_day43282.5259
GSM1296054J_lesional_day43406.364
GSM1296049K_lesional_day43230.2855
GSM1296055W_lesional_day43280.4857
GSM1296053X_lesional_day43403.6264
GSM1296058Z_lesional_day43500.1268
GSM1296051F_lesional_day4322355
GSM1296056O_lesional_day43482.5668
GSM1296065S_lesional_day43375.0363
GSM1296061T_lesional_day43775.0975
GSM1296095A_non-lesional_pre-dose410.0865
GSM1296120B_non-lesional_pre-dose158.5847
GSM1296077C_non-lesional_pre-dose238.2456
GSM1296093D_non-lesional_pre-dose427.8264
GSM1296104E_non-lesional_pre-dose311.6960
GSM1296079F_non-lesional_pre-dose305.4360
GSM1296108G_non-lesional_pre-dose265.7356
GSM1296110H_non-lesional_pre-dose285.7357
GSM1296081I_non-lesional_pre-dose334.3361
GSM1296091J_non-lesional_pre-dose328.0461
GSM1296075K_non-lesional_pre-dose172.4151
GSM1296112L_non-lesional_pre-dose268.0555
GSM1296100M_non-lesional_pre-dose590.8770
GSM1296087O_non-lesional_pre-dose303.7260
GSM1296118P_non-lesional_pre-dose260.5855
GSM1296114Q_non-lesional_pre-dose202.3251
GSM1296097R_non-lesional_pre-dose384.0263
GSM1296106S_non-lesional_pre-dose432.965
GSM1296102U_non-lesional_pre-dose452.9565
GSM1296122V_non-lesional_pre-dose168.848
GSM1296089W_non-lesional_pre-dose361.2861
GSM1296083X_non-lesional_pre-dose554.8169
GSM1296116Y_non-lesional_pre-dose223.6152
GSM1296085Z_non-lesional_pre-dose365.6462