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GTR Home > Conditions/Phenotypes > Neural tube defect

Neural tube defect

Synonyms
Neural tube defects

Summary

A neural tube defect arises when the neural tube, the embryonic precursor of the brain and spinal cord, fails to close during neurulation. The cranial region (anencephaly) or the low spine (open spina bifida; myelomeningocele) are most commonly affected although, in the severe NTD craniorachischisis, almost the entire neural tube remains open, from midbrain to low spine. [from HPO]

Available tests

26 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Clinical tests (25 available)

Molecular Genetics Tests

Research tests

Genes See tests for all associated and related genes

  • Also known as: GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF, CCL2
    Summary: C-C motif chemokine ligand 2

  • Also known as: CPLANE3, FY, NTD, FUZ
    Summary: fuzzy planar cell polarity protein

  • Also known as: SAVA, T, TFT, TBXT
    Summary: T-box transcription factor T

  • Also known as: KITENIN, LPP2, STB2, STBM2, VANGL1
    Summary: VANGL planar cell polarity protein 1

  • Also known as: LPP1, LTAP, STB1, STBM, STBM1, VANGL2
    Summary: VANGL planar cell polarity protein 2

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