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GTR Home > Conditions/Phenotypes > Keratosis palmoplantaris striata 2

Keratosis palmoplantaris striata 2

Synonyms
KERATODERMA, PALMOPLANTAR, STRIATE FORM II; Keratosis palmoplantaris striata II; STRIATE PALMOPLANTAR KERATODERMA II

Summary

PPKS2 is characterized by linear hyperkeratosis of the palms, which is particularly evident in affected individuals who perform manual labor. Hyperkeratosis of the soles primarily involves pressure points, and diffuse background palmoplantar thickening may also be present. (Armstrong et al., 1999; Whittock et al., 1999). For a discussion of genetic heterogeneity of the striate form of palmoplantar keratoderma, see PPKS1 (148700). [from OMIM]

Available tests

50 tests are in the database for this condition.

Clinical tests (50 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: DCWHKTA, DP, DSP
    Summary: desmoplakin

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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