Amyotrophic lateral sclerosis, susceptibility to, 25

Summary

Amyotrophic lateral sclerosis is a neurodegenerative disorder clinically characterized by rapidly progressive muscle weakness and death due to respiratory failure. ALS25 may have a lower median age at onset (46.5 years) and longer median survival (10 years) than that found in epidemiologic studies (62.5 years and 20 to 30 months, respectively) (Nicolas et al., 2018). [from OMIM]

Available tests

13 tests are in the database for this condition.

Clinical tests (13 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

Associated genes Help
Genes reported to contribute to the condition.

KIF5A
104 tests
Also known as: ALS25, D12S1889, MY050, NEIMY, NKHC, SPG10, KIF5A
Summary: kinesin family member 5A

Imported from Human Phenotype Ontology (HPO)

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Abnormality of the nervous system
- Amyotrophic lateral sclerosis
  Amyotrophic lateral sclerosis
  - MedGen UID: 274
  - Concept ID: C0002736
  - Finding: Disease or Syndrome
  Abnormality of the nervous system
  See: Feature record | Search on this feature

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Clinical resources

Molecular resources

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