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GTR Home > Conditions/Phenotypes > Spermatogenic failure 41

Spermatogenic failure 41

Summary

Spermatogenic failure-41 (SPGF41) is characterized by infertility due to multiple morphologic abnormalities of the flagella (MMAF). Patient semen analysis has also shown oligozoospermia, and the flagellar abnormalities include short, absent, coiled, and irregular-caliber flagella. Some sperm show tapered heads and acrosomal abnormalities (Beurois et al., 2019). For a discussion of genetic heterogeneity of spermatogenic failure, see SPGF1 (258150). [from OMIM]

Available tests

2 tests are in the database for this condition.

Clinical tests (2 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: SPGF41, TTC18, CFAP70
    Summary: cilia and flagella associated protein 70

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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