DRD5 dopamine receptor D5
Gene ID: 1816, updated on 4-Jan-2025Gene type: protein coding
Also known as: DBDR; DRD1B; DRD1L2
- See all available tests in GTR for this gene
- Go to complete Gene record for DRD5
- Go to Variation Viewer for DRD5 variants
Summary
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Blepharospasm, benign essential, susceptibility to | not available |
| Hereditary attention deficit-hyperactivity disorder | not available |
Copy number response
| Description |
|---|
| Copy number response Haploinsufficency No evidence available (Last evaluated 2012-05-15) ClinGen Genome Curation PageTriplosensitivity No evidence available (Last evaluated 2012-05-15) ClinGen Genome Curation Page |
Genomic context
- Location:
- 4p16.1
- Sequence:
- Chromosome: 4; NC_000004.12 (9781634..9784009)
- Total number of exons:
- 1
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for DRD5 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- DRD5 database
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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