LRP4 LDL receptor related protein 4
Gene ID: 4038, updated on 10-Dec-2024Gene type: protein coding
Also known as: CLSS; CMS17; LRP-4; LRP10; MEGF7; SOST2
- See all available tests in GTR for this gene
- Go to complete Gene record for LRP4
- Go to Variation Viewer for LRP4 variants
Summary
This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Biological, clinical and population relevance of 95 loci for blood lipids. GeneReviews: Not available | |
| Cenani-Lenz syndactyly syndrome | See labs |
| Congenital myasthenic syndrome 17 | See labs |
| Discovery and refinement of loci associated with lipid levels. GeneReviews: Not available | |
| Genetic predictors of fibrin D-dimer levels in healthy adults. GeneReviews: Not available | |
| New sequence variants associated with bone mineral density. GeneReviews: Not available | |
| Sclerosteosis 2 | See labs |
Genomic context
- Location:
- 11p11.2
- Sequence:
- Chromosome: 11; NC_000011.10 (46856717..46918550, complement)
- Total number of exons:
- 41
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for LRP4 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- LRP4 database
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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