H4C9 H4 clustered histone 9
Gene ID: 8294, updated on 4-Jan-2025Gene type: protein coding
Also known as: H4M; H4/m; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4FM; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; HIST1H4I; TEVANED4; TEBIVANED4
- See all available tests in GTR for this gene
- Go to complete Gene record for H4C9
- Go to Variation Viewer for H4C9 variants
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Tessadori-Van Haaften neurodevelopmental syndrome 4 | not available |
Genomic context
- Location:
- 6p22.1
- Sequence:
- Chromosome: 6; NC_000006.12 (27139282..27139678)
- Total number of exons:
- 1
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for H4C9 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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