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Cervical benign neoplasm

MedGen UID:
102300
•Concept ID:
C0153997
•
Neoplastic Process
Synonyms: Benign Cervical Neoplasm; benign cervical neoplasm; Benign Cervix Uteri Neoplasm; benign cervix uteri neoplasm; Benign Cervix Uteri Neoplasm NOS; Benign Cervix Uteri Tumor; benign cervix uteri tumor; benign cervix uteri tumour; Benign neoplasm of cervix uteri; Benign Neoplasm of Cervix Uteri; benign neoplasm of cervix uteri; Benign Neoplasm of the Cervix Uteri; benign neoplasm of the cervix uteri; Benign Neoplasm of the Uterine Cervix; benign neoplasm of the uterine cervix; Benign neoplasm of uterine cervix; Benign Neoplasm of Uterine Cervix; benign neoplasm of uterine cervix; Benign tumor of cervix; Benign Tumor of Cervix Uteri; benign tumor of cervix uteri; Benign Tumor of the Cervix Uteri; benign tumor of the cervix uteri; Benign Tumor of the Uterine Cervix; benign tumor of the uterine cervix; Benign Tumor of Uterine Cervix; benign tumor of uterine cervix; benign tumour of cervix uteri; benign tumour of the cervix uteri; benign tumour of the uterine cervix; benign tumour of uterine cervix; Benign Uterine Cervix Neoplasm; benign uterine cervix neoplasm; Benign Uterine Cervix Tumor; benign uterine cervix tumor; benign uterine cervix tumour; cervical benign neoplasm; uterine cervix benign neoplasm
SNOMED CT: Benign tumor of cervix (92056006); Benign neoplasm of uterine cervix (92056006); Benign neoplasm of cervix uteri (92056006)
 
Monarch Initiative: MONDO:0000644

Definition

A neoplasm that arises from the cervix and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include squamous papilloma, endocervical polyp, and rhabdomyoma. [from NCI]

Professional guidelines

PubMed

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†.
Filetti S, Durante C, Hartl D, Leboulleux S, Locati LD, Newbold K, Papotti MG, Berruti A; ESMO Guidelines Committee. Electronic address: [email protected]
Ann Oncol 2019 Dec 1;30(12):1856-1883. doi: 10.1093/annonc/mdz400. PMID: 31549998
Cervical cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Marth C, Landoni F, Mahner S, McCormack M, Gonzalez-Martin A, Colombo N; ESMO Guidelines Committee
Ann Oncol 2017 Jul 1;28(suppl_4):iv72-iv83. doi: 10.1093/annonc/mdx220. PMID: 28881916

Recent clinical studies

Etiology

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Malignant cervical masses in children.
Brigger MT, Cunningham MJ
Otolaryngol Clin North Am 2015 Feb;48(1):59-77. doi: 10.1016/j.otc.2014.09.006. PMID: 25442128
Evaluation and staging of the neck in patients with malignant disease.
Shum JW, Dierks EJ
Oral Maxillofac Surg Clin North Am 2014 May;26(2):209-21. Epub 2014 Mar 20 doi: 10.1016/j.coms.2014.01.007. PMID: 24656885

Diagnosis

Pediatric Gnathic Bony and Mesenchymal Tumors.
Liu Y, Housley Smith M, Patel PB, Bilodeau EA
Pediatr Dev Pathol 2023 Nov-Dec;26(6):621-641. Epub 2023 May 26 doi: 10.1177/10935266231170744. PMID: 37232383
Congenital Neck Mass.
Sprewell AR, Holman JL, Kiell EP
Neoreviews 2021 Jun;22(6):e415-e419. doi: 10.1542/neo.22-6-e415. PMID: 34074649
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Pediatric neck masses.
Geddes G, Butterly MM, Patel SM, Marra S
Pediatr Rev 2013 Mar;34(3):115-24; quiz 125. doi: 10.1542/pir.34-3-115. PMID: 23457198
Microcolpohysteroscopy.
Kumar A, Kumar A
J Am Assoc Gynecol Laparosc 2004 May;11(2):131-2. doi: 10.1016/s1074-3804(05)60187-9. PMID: 15200763

Therapy

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer.
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Neck dissection: past and present.
Ducic Y, Young L, McIntyre J
Minerva Chir 2010 Feb;65(1):45-58. PMID: 20212417
Cancer chemoprevention.
Lippman SM, Benner SE, Hong WK
J Clin Oncol 1994 Apr;12(4):851-73. doi: 10.1200/JCO.1994.12.4.851. PMID: 8151328
Cervicitis.
Pawson ME
Clin Obstet Gynaecol 1981 Apr;8(1):201-8. PMID: 7261522

Prognosis

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer.
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Global Cancer Incidence and Mortality Rates and Trends--An Update.
Torre LA, Siegel RL, Ward EM, Jemal A
Cancer Epidemiol Biomarkers Prev 2016 Jan;25(1):16-27. Epub 2015 Dec 14 doi: 10.1158/1055-9965.EPI-15-0578. PMID: 26667886
Infrahyoid neck.
Sigal R
Radiol Clin North Am 1998 Sep;36(5):781-99, v. doi: 10.1016/s0033-8389(05)70064-6. PMID: 9747189
Cervical ganglioneuroblastoma.
Al-Jassim AH
J Laryngol Otol 1987 Mar;101(3):296-301. doi: 10.1017/s0022215100101677. PMID: 3572236

Clinical prediction guides

Comprehensive and clinically accurate head and neck cancer organs-at-risk delineation on a multi-institutional study.
Ye X, Guo D, Ge J, Yan S, Xin Y, Song Y, Yan Y, Huang BS, Hung TM, Zhu Z, Peng L, Ren Y, Liu R, Zhang G, Mao M, Chen X, Lu Z, Li W, Chen Y, Huang L, Xiao J, Harrison AP, Lu L, Lin CY, Jin D, Ho TY
Nat Commun 2022 Oct 17;13(1):6137. doi: 10.1038/s41467-022-33178-z. PMID: 36253346Free PMC Article
Dynamic Contrast-Enhanced MR Imaging in Head and Neck Cancer.
Kabadi SJ, Fatterpekar GM, Anzai Y, Mogen J, Hagiwara M, Patel SH
Magn Reson Imaging Clin N Am 2018 Feb;26(1):135-149. Epub 2017 Oct 21 doi: 10.1016/j.mric.2017.08.008. PMID: 29128001
Diffusion-Weighted Imaging in Head and Neck Cancer: Technique, Limitations, and Applications.
Connolly M, Srinivasan A
Magn Reson Imaging Clin N Am 2018 Feb;26(1):121-133. Epub 2017 Oct 14 doi: 10.1016/j.mric.2017.08.011. PMID: 29128000
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Infrahyoid neck.
Sigal R
Radiol Clin North Am 1998 Sep;36(5):781-99, v. doi: 10.1016/s0033-8389(05)70064-6. PMID: 9747189

Recent systematic reviews

Treatment of Angiosarcoma of the Head and Neck: A Systematic Review.
Houpe JE, Seger EW, Neill BC, Kang BY, Hocker TLH, Alam M, Tolkachjov SN
Cutis 2023 May;111(5):247-251. doi: 10.12788/cutis.0767. PMID: 37406332
Elective neck dissection in salivary gland malignancies: Systematic review and meta-analysis.
Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810
Mortality due to cancer treatment delay: systematic review and meta-analysis.
Hanna TP, King WD, Thibodeau S, Jalink M, Paulin GA, Harvey-Jones E, O'Sullivan DE, Booth CM, Sullivan R, Aggarwal A
BMJ 2020 Nov 4;371:m4087. doi: 10.1136/bmj.m4087. PMID: 33148535Free PMC Article
Educational Interventions for Cervical Cancer Screening Behavior of Women: A Systematic Review.
Saei Ghare Naz M, Kariman N, Ebadi A, Ozgoli G, Ghasemi V, Rashidi Fakari F
Asian Pac J Cancer Prev 2018 Apr 25;19(4):875-884. doi: 10.22034/APJCP.2018.19.4.875. PMID: 29693331Free PMC Article
Incomplete excision of cervical precancer as a predictor of treatment failure: a systematic review and meta-analysis.
Arbyn M, Redman CWE, Verdoodt F, Kyrgiou M, Tzafetas M, Ghaem-Maghami S, Petry KU, Leeson S, Bergeron C, Nieminen P, Gondry J, Reich O, Moss EL
Lancet Oncol 2017 Dec;18(12):1665-1679. Epub 2017 Nov 7 doi: 10.1016/S1470-2045(17)30700-3. PMID: 29126708

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