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Carcinomatosis

MedGen UID:
104704
•Concept ID:
C0205699
•
Neoplastic Process
Synonym: Carcinomatoses
SNOMED CT: Carcinomatosis (7010000); Disseminated carcinomatosis (307593001); Carcinomatosis (307593001)

Definition

Carcinoma that has spread diffusely to an anatomic site or throughout the body. [from NCI]

Professional guidelines

PubMed

Evidence-based approach to diagnosis and management of abdominal tuberculosis.
Jha DK, Pathiyil MM, Sharma V
Indian J Gastroenterol 2023 Feb;42(1):17-31. Epub 2023 Mar 11 doi: 10.1007/s12664-023-01343-x. PMID: 36899289Free PMC Article
ESGO/ISUOG/IOTA/ESGE Consensus Statement on pre-operative diagnosis of ovarian tumors.
Timmerman D, Planchamp F, Bourne T, Landolfo C, du Bois A, Chiva L, Cibula D, Concin N, Fischerova D, Froyman W, Gallardo Madueño G, Lemley B, Loft A, Mereu L, Morice P, Querleu D, Testa AC, Vergote I, Vandecaveye V, Scambia G, Fotopoulou C
Int J Gynecol Cancer 2021 Jul;31(7):961-982. Epub 2021 Jun 10 doi: 10.1136/ijgc-2021-002565. PMID: 34112736Free PMC Article
Micronodular lung disease on high-resolution CT: patterns and differential diagnosis.
Kim J, Dabiri B, Hammer MM
Clin Radiol 2021 Jun;76(6):399-406. Epub 2021 Feb 7 doi: 10.1016/j.crad.2020.12.025. PMID: 33563413

Recent clinical studies

Etiology

Leveraging Molecular and Immune-Based Therapies in Leptomeningeal Metastases.
Wilcox JA, Boire AA
CNS Drugs 2023 Jan;37(1):45-67. Epub 2022 Dec 6 doi: 10.1007/s40263-022-00975-5. PMID: 36474108Free PMC Article
A Palliative Approach to Management of Peritoneal Carcinomatosis and Malignant Ascites.
Bleicher J, Lambert LA
Surg Oncol Clin N Am 2021 Jul;30(3):475-490. doi: 10.1016/j.soc.2021.02.004. PMID: 34053663
ANG1005, a Brain-Penetrating Peptide-Drug Conjugate, Shows Activity in Patients with Breast Cancer with Leptomeningeal Carcinomatosis and Recurrent Brain Metastases.
Kumthekar P, Tang SC, Brenner AJ, Kesari S, Piccioni DE, Anders C, Carrillo J, Chalasani P, Kabos P, Puhalla S, Tkaczuk K, Garcia AA, Ahluwalia MS, Wefel JS, Lakhani N, Ibrahim N
Clin Cancer Res 2020 Jun 15;26(12):2789-2799. Epub 2020 Jan 22 doi: 10.1158/1078-0432.CCR-19-3258. PMID: 31969331
Management of neoplastic meningitis.
Roth P, Weller M
Chin Clin Oncol 2015 Jun;4(2):26. doi: 10.3978/j.issn.2304-3865.2015.05.02. PMID: 26112812
US of the peritoneum.
Hanbidge AE, Lynch D, Wilson SR
Radiographics 2003 May-Jun;23(3):663-84; discussion 684-5. doi: 10.1148/rg.233025712. PMID: 12740467

Diagnosis

Corticosteroids for pulmonary lymphangitic carcinomatosis.
Takimoto T
BMJ Support Palliat Care 2024 Jan 8;13(e3):e951-e952. doi: 10.1136/spcare-2022-003983. PMID: 36302614
Leptomeningeal Metastasis: A Review of the Pathophysiology, Diagnostic Methodology, and Therapeutic Landscape.
Nguyen A, Nguyen A, Dada OT, Desai PD, Ricci JC, Godbole NB, Pierre K, Lucke-Wold B
Curr Oncol 2023 Jun 19;30(6):5906-5931. doi: 10.3390/curroncol30060442. PMID: 37366925Free PMC Article
Leptomeningeal Metastasis from Non-Small Cell Lung Cancer and Current Landscape of Treatments.
Ozcan G, Singh M, Vredenburgh JJ
Clin Cancer Res 2023 Jan 4;29(1):11-29. doi: 10.1158/1078-0432.CCR-22-1585. PMID: 35972437
Palliative Management of Peritoneal Metastases.
Lambert LA, Wiseman J
Ann Surg Oncol 2018 Aug;25(8):2165-2171. Epub 2018 Jan 30 doi: 10.1245/s10434-018-6335-7. PMID: 29383612
Leptomeningeal disease.
Groves MD
Neurosurg Clin N Am 2011 Jan;22(1):67-78, vii. doi: 10.1016/j.nec.2010.08.006. PMID: 21109151

Therapy

Corticosteroids for pulmonary lymphangitic carcinomatosis.
Takimoto T
BMJ Support Palliat Care 2024 Jan 8;13(e3):e951-e952. doi: 10.1136/spcare-2022-003983. PMID: 36302614
Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial.
Arjona-Sánchez A, Espinosa-Redondo E, Gutiérrez-Calvo A, Segura-Sampedro JJ, Pérez-Viejo E, Concepción-Martín V, Sánchez-García S, García-Fadrique A, Prieto-Nieto I, Barrios-Sanchez P, Torres-Melero J, Ramírez Faraco M, Prada-Villaverde A, Carrasco-Campos J, Artiles-Armas M, Villarejo-Campos P, Ortega-Pérez G, Boldo-Roda E, Sánchez-Hidalgo JM, Casado-Adam A, Rodríguez-Ortiz L, Aranda E, Cano-Osuna MT, Díaz-López C, Romero-Ruiz A, Briceño-Delgado J, Rufián-Peña S; Grupo Español de Carcinomatosis Peritoneal
JAMA Surg 2023 Jul 1;158(7):683-691. doi: 10.1001/jamasurg.2023.0662. PMID: 37099280Free PMC Article
Leptomeningeal Metastasis from Non-Small Cell Lung Cancer and Current Landscape of Treatments.
Ozcan G, Singh M, Vredenburgh JJ
Clin Cancer Res 2023 Jan 4;29(1):11-29. doi: 10.1158/1078-0432.CCR-22-1585. PMID: 35972437
Randomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis.
Yang JT, Wijetunga NA, Pentsova E, Wolden S, Young RJ, Correa D, Zhang Z, Zheng J, Steckler A, Bucwinska W, Bernstein A, Betof Warner A, Yu H, Kris MG, Seidman AD, Wilcox JA, Malani R, Lin A, DeAngelis LM, Lee NY, Powell SN, Boire A
J Clin Oncol 2022 Nov 20;40(33):3858-3867. Epub 2022 Jul 8 doi: 10.1200/JCO.22.01148. PMID: 35802849Free PMC Article
Management of ascites.
Rochling FA, Zetterman RK
Drugs 2009;69(13):1739-60. doi: 10.2165/11316390-000000000-00000. PMID: 19719331

Prognosis

Palliative Management of Peritoneal Metastases.
Lambert LA, Wiseman J
Ann Surg Oncol 2018 Aug;25(8):2165-2171. Epub 2018 Jan 30 doi: 10.1245/s10434-018-6335-7. PMID: 29383612
Peritoneal carcinomatosis of colorectal origin: Incidence, prognosis and treatment options.
Klaver YL, Lemmens VE, Nienhuijs SW, Luyer MD, de Hingh IH
World J Gastroenterol 2012 Oct 21;18(39):5489-94. doi: 10.3748/wjg.v18.i39.5489. PMID: 23112540Free PMC Article
Neoplastic meningitis.
Van Horn A, Chamberlain MC
J Support Oncol 2012 Mar-Apr;10(2):45-53. Epub 2011 Sep 23 doi: 10.1016/j.suponc.2011.06.002. PMID: 22005214
Pseudomyxoma peritonei: the 'controversial' disease.
Galani E, Marx GM, Steer CB, Culora G, Harper PG
Int J Gynecol Cancer 2003 Jul-Aug;13(4):413-8. doi: 10.1046/j.1525-1438.2003.13318.x. PMID: 12911716
Extraovarian primary peritoneal carcinoma.
Eltabbakh GH, Piver MS
Oncology (Williston Park) 1998 Jun;12(6):813-9; discussion 820, 825-6. PMID: 9644683

Clinical prediction guides

A Consensus for Classification and Pathologic Reporting of Pseudomyxoma Peritonei and Associated Appendiceal Neoplasia: The Results of the Peritoneal Surface Oncology Group International (PSOGI) Modified Delphi Process.
Carr NJ, Cecil TD, Mohamed F, Sobin LH, Sugarbaker PH, González-Moreno S, Taflampas P, Chapman S, Moran BJ; Peritoneal Surface Oncology Group International
Am J Surg Pathol 2016 Jan;40(1):14-26. doi: 10.1097/PAS.0000000000000535. PMID: 26492181
Management of neoplastic meningitis.
Roth P, Weller M
Chin Clin Oncol 2015 Jun;4(2):26. doi: 10.3978/j.issn.2304-3865.2015.05.02. PMID: 26112812
Meningeal carcinomatosis in solid tumors.
Martins SJ, Azevedo CR, Chinen LT, Cruz MR, Peterlevitz MA, Gimenes DL
Arq Neuropsiquiatr 2011 Dec;69(6):973-80. doi: 10.1590/s0004-282x2011000700024. PMID: 22297890
Intraperitoneal photodynamic therapy.
Cengel KA, Glatstein E, Hahn SM
Cancer Treat Res 2007;134:493-514. doi: 10.1007/978-0-387-48993-3_34. PMID: 17633077
Meningeal carcinomatosis.
HAWKINS D, BROWN D
Can Med Assoc J 1963 Feb 2;88(5):225-8. PMID: 13953212Free PMC Article

Recent systematic reviews

Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis.
Wijaya JH, Patel UD, Quintero-Consuegra MD, Aguilera-Peña MP, Madriñán-Navia HJ, Putra AW, July J, Kataria S
J Neurooncol 2023 Dec;165(3):431-438. Epub 2023 Nov 29 doi: 10.1007/s11060-023-04519-9. PMID: 38019327
Trastuzumab Deruxtecan-Induced Interstitial Lung Disease/Pneumonitis in ERBB2-Positive Advanced Solid Malignancies: A Systematic Review.
Abuhelwa Z, Alloghbi A, Alqahtani A, Nagasaka M
Drugs 2022 Jun;82(9):979-987. Epub 2022 Jun 27 doi: 10.1007/s40265-022-01736-w. PMID: 35759121Free PMC Article
Clinical studies in CRS and HIPEC: Trials, tribulations, and future directions-A systematic review.
Morano WF, Khalili M, Chi DS, Bowne WB, Esquivel J
J Surg Oncol 2018 Feb;117(2):245-259. Epub 2017 Nov 9 doi: 10.1002/jso.24813. PMID: 29120491Free PMC Article
Bowel obstruction and peritoneal carcinomatosis in the elderly. A systematic review.
Santangelo ML, Grifasi C, Criscitiello C, Giuliano M, Calogero A, Dodaro C, Incollingo P, Rupealta N, Candida M, Chiacchio G, Riccio E, Pisani A, Tammaro V, Carlomagno N
Aging Clin Exp Res 2017 Feb;29(Suppl 1):73-78. Epub 2016 Nov 11 doi: 10.1007/s40520-016-0656-9. PMID: 27837464
Laparoscopic robot-assisted major hepatectomy.
Boggi U, Caniglia F, Amorese G
J Hepatobiliary Pancreat Sci 2014 Jan;21(1):3-10. Epub 2013 Sep 30 doi: 10.1002/jhbp.34. PMID: 24115394

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