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Conjunctival subepithelial fibrosis

MedGen UID:: 1052586
•Concept ID:: CN378438
•: Finding

HPO:	HP:6001090

Definition

fine white linear scars under intact conjunctival epithelium. This scarring appears in areas of previous conjunctival ulceration or pseudomembrane formation, weeks to months after the insult is healed. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVConjunctival subepithelial fibrosis

Abnormality of the head
- Abnormality of the face
  - Abnormality of the orbital region
    - Abnormality of the ocular adnexa
      - Abnormal ocular adnexa morphology
        Abnormal conjunctiva morphology
        Conjunctival subepithelial fibrosis

Professional guidelines

PubMed

Cicatricial pemphigoid: diagnosis and treatment.

Nguyen QD, Foster CS
Int Ophthalmol Clin 1996 Winter;36(1):41-60. doi: 10.1097/00004397-199603610-00007. PMID: 8778068

Recent clinical studies

Etiology

Conjunctival subepithelial fibrosis and meibomian gland atrophy in ocular graft-versus-host disease.

Kusne Y, Temkit M, Khera N, Patel DR, Shen JF
Ocul Surf 2017 Oct;15(4):784-788. Epub 2017 Aug 5 doi: 10.1016/j.jtos.2017.08.002. PMID: 28789979

Visual acuity and anterior segment findings in chronic graft-versus-host disease.

Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943

Diagnosis

Visual acuity and anterior segment findings in chronic graft-versus-host disease.

Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943

Therapy

Visual acuity and anterior segment findings in chronic graft-versus-host disease.

Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943

Prognosis

Visual acuity and anterior segment findings in chronic graft-versus-host disease.

Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943

Clinical prediction guides

Conjunctival subepithelial fibrosis and meibomian gland atrophy in ocular graft-versus-host disease.

Kusne Y, Temkit M, Khera N, Patel DR, Shen JF
Ocul Surf 2017 Oct;15(4):784-788. Epub 2017 Aug 5 doi: 10.1016/j.jtos.2017.08.002. PMID: 28789979

Visual acuity and anterior segment findings in chronic graft-versus-host disease.

Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943

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