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Abnormal urinary organic compound level

MedGen UID:
1052673
Concept ID:
CN377362
Finding
HPO: HP:6000531

Definition

The amount of an organic compound in the urine, normalized for urine concentration, is outside the limits of normal. An organic compound is defined here as a chemical compound that contains a carbon-hydrogen or carbon-carbon bond, although some other definitions exist. Examples of organic compounds includes alkanes, alkenes, alkynes, aromatic compounds, alcohols, ketones, aldehydes, carboxylic acids, and esters. [from HPO]

Professional guidelines

PubMed

Wang F, Liang L, Ling S, Yu Y, Chen T, Xu F, Gong Z, Han L
Zhejiang Da Xue Xue Bao Yi Xue Ban 2022 Jun 25;51(3):298-305. doi: 10.3724/zdxbyxb-2022-0194. PMID: 36207831Free PMC Article
Hamilton JL, Evans SG, Bakshi M
Am Fam Physician 2020 Jun 15;101(12):721-729. PMID: 32538597
Bridgeman MB, Shah M, Foote E
Nephrol Dial Transplant 2019 Dec 1;34(Suppl 3):iii45-iii50. doi: 10.1093/ndt/gfz223. PMID: 31800078

Recent clinical studies

Etiology

Azushima K, Kovalik JP, Yamaji T, Ching J, Chng TW, Guo J, Liu JJ, Nguyen M, Sakban RB, George SE, Tan PH, Lim SC, Gurley SB, Coffman TM
Kidney Int 2023 Dec;104(6):1135-1149. Epub 2023 Oct 16 doi: 10.1016/j.kint.2023.08.006. PMID: 37843477
Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099Free PMC Article
Lin M, Hua R, Ma J, Zhou Y, Li P, Xu X, Yu Z, Quan S
Environ Int 2021 Feb;147:106298. Epub 2020 Dec 30 doi: 10.1016/j.envint.2020.106298. PMID: 33387880
Hamilton JL, Evans SG, Bakshi M
Am Fam Physician 2020 Jun 15;101(12):721-729. PMID: 32538597
Hubers SA, Brown NJ
Circulation 2016 Mar 15;133(11):1115-24. doi: 10.1161/CIRCULATIONAHA.115.018622. PMID: 26976916Free PMC Article

Diagnosis

Morava E, Oglesbee D
Handb Clin Neurol 2023;194:167-172. doi: 10.1016/B978-0-12-821751-1.00012-9. PMID: 36813311
Krečak I, Babić G, Skelin M
Acta Dermatovenerol Croat 2022 Jul;30(1):59-60. PMID: 36153722
Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099Free PMC Article
Hamilton JL, Evans SG, Bakshi M
Am Fam Physician 2020 Jun 15;101(12):721-729. PMID: 32538597
Hubers SA, Brown NJ
Circulation 2016 Mar 15;133(11):1115-24. doi: 10.1161/CIRCULATIONAHA.115.018622. PMID: 26976916Free PMC Article

Therapy

Azushima K, Kovalik JP, Yamaji T, Ching J, Chng TW, Guo J, Liu JJ, Nguyen M, Sakban RB, George SE, Tan PH, Lim SC, Gurley SB, Coffman TM
Kidney Int 2023 Dec;104(6):1135-1149. Epub 2023 Oct 16 doi: 10.1016/j.kint.2023.08.006. PMID: 37843477
Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099Free PMC Article
Hamilton JL, Evans SG, Bakshi M
Am Fam Physician 2020 Jun 15;101(12):721-729. PMID: 32538597
Reiss AB, Miyawaki N, Moon J, Kasselman LJ, Voloshyna I, D'Avino R Jr, De Leon J
Atherosclerosis 2018 Nov;278:49-59. Epub 2018 Aug 30 doi: 10.1016/j.atherosclerosis.2018.08.046. PMID: 30253289
Hubers SA, Brown NJ
Circulation 2016 Mar 15;133(11):1115-24. doi: 10.1161/CIRCULATIONAHA.115.018622. PMID: 26976916Free PMC Article

Prognosis

Azushima K, Kovalik JP, Yamaji T, Ching J, Chng TW, Guo J, Liu JJ, Nguyen M, Sakban RB, George SE, Tan PH, Lim SC, Gurley SB, Coffman TM
Kidney Int 2023 Dec;104(6):1135-1149. Epub 2023 Oct 16 doi: 10.1016/j.kint.2023.08.006. PMID: 37843477
Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099Free PMC Article
Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV
Cell Metab 2021 May 4;33(5):1042-1061.e7. doi: 10.1016/j.cmet.2021.04.004. PMID: 33951465Free PMC Article
Hubers SA, Brown NJ
Circulation 2016 Mar 15;133(11):1115-24. doi: 10.1161/CIRCULATIONAHA.115.018622. PMID: 26976916Free PMC Article
Naschitz JE, Yeshurun D, Shahar J
Angiology 1990 Nov;41(11):893-900. doi: 10.1177/000331979004101101. PMID: 2244692

Clinical prediction guides

Azushima K, Kovalik JP, Yamaji T, Ching J, Chng TW, Guo J, Liu JJ, Nguyen M, Sakban RB, George SE, Tan PH, Lim SC, Gurley SB, Coffman TM
Kidney Int 2023 Dec;104(6):1135-1149. Epub 2023 Oct 16 doi: 10.1016/j.kint.2023.08.006. PMID: 37843477
Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099Free PMC Article
Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV
Cell Metab 2021 May 4;33(5):1042-1061.e7. doi: 10.1016/j.cmet.2021.04.004. PMID: 33951465Free PMC Article
Lin M, Hua R, Ma J, Zhou Y, Li P, Xu X, Yu Z, Quan S
Environ Int 2021 Feb;147:106298. Epub 2020 Dec 30 doi: 10.1016/j.envint.2020.106298. PMID: 33387880
Hamilton JL, Evans SG, Bakshi M
Am Fam Physician 2020 Jun 15;101(12):721-729. PMID: 32538597

Recent systematic reviews

Beiner E, Lucas V, Reichert J, Buhai DV, Jesinghaus M, Vock S, Drusko A, Baumeister D, Eich W, Friederich HC, Tesarz J
Pain 2023 Jul 1;164(7):1416-1427. Epub 2023 Jan 5 doi: 10.1097/j.pain.0000000000002857. PMID: 36728497
Häuser W, Urrútia G, Tort S, Uçeyler N, Walitt B
Cochrane Database Syst Rev 2013 Jan 31;(1):CD010292. doi: 10.1002/14651858.CD010292. PMID: 23440848
Escribano J, Balaguer A, Pagone F, Feliu A, Roqué I Figuls M
Cochrane Database Syst Rev 2009 Jan 21;2009(1):CD004754. doi: 10.1002/14651858.CD004754.pub2. PMID: 19160242Free PMC Article

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