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Anti-factor V antibody positivity

MedGen UID:
1053245
•Concept ID:
CN377323
•
Finding
Synonym: Anti-FV antibody positivity
 
HPO: HP:6000492

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against factor V. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-factor V antibody positivity

Recent clinical studies

Etiology

Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays.
Artim-Esen B, Pericleous C, Mackie I, Ripoll VM, Latchman D, Isenberg D, Rahman A, Ioannou Y, Giles I
Arthritis Res Ther 2015 Mar 7;17(1):47. doi: 10.1186/s13075-015-0568-7. PMID: 25890027Free PMC Article

Diagnosis

Targeting Acquired Hemophilia A with Rheumatoid Arthritis by a Rituximab Shot: A Case Report and Review of the Literature.
Ghozlani I, Mounach A, Ghazi M, Kherrab A, Niamane R
Am J Case Rep 2018 May 21;19:582-588. doi: 10.12659/AJCR.908854. PMID: 29780157Free PMC Article
Conceptions and misconceptions in testing for lupus anticoagulants.
Exner T
J Autoimmun 2000 Sep;15(2):179-83. doi: 10.1006/jaut.2000.0392. PMID: 10968906
Acute leukemia with megakaryocytic differentiation: a study of 12 cases identified immunocytochemically.
Huang MJ, Li CY, Nichols WL, Young JH, Katzmann JA
Blood 1984 Aug;64(2):427-39. PMID: 6378277

Therapy

Targeting Acquired Hemophilia A with Rheumatoid Arthritis by a Rituximab Shot: A Case Report and Review of the Literature.
Ghozlani I, Mounach A, Ghazi M, Kherrab A, Niamane R
Am J Case Rep 2018 May 21;19:582-588. doi: 10.12659/AJCR.908854. PMID: 29780157Free PMC Article
Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms.
Joop K, Berckmans RJ, Nieuwland R, Berkhout J, Romijn FP, Hack CE, Sturk A
Thromb Haemost 2001 May;85(5):810-20. PMID: 11372673

Prognosis

Targeting Acquired Hemophilia A with Rheumatoid Arthritis by a Rituximab Shot: A Case Report and Review of the Literature.
Ghozlani I, Mounach A, Ghazi M, Kherrab A, Niamane R
Am J Case Rep 2018 May 21;19:582-588. doi: 10.12659/AJCR.908854. PMID: 29780157Free PMC Article
Acute leukemia with megakaryocytic differentiation: a study of 12 cases identified immunocytochemically.
Huang MJ, Li CY, Nichols WL, Young JH, Katzmann JA
Blood 1984 Aug;64(2):427-39. PMID: 6378277

Clinical prediction guides

Targeting Acquired Hemophilia A with Rheumatoid Arthritis by a Rituximab Shot: A Case Report and Review of the Literature.
Ghozlani I, Mounach A, Ghazi M, Kherrab A, Niamane R
Am J Case Rep 2018 May 21;19:582-588. doi: 10.12659/AJCR.908854. PMID: 29780157Free PMC Article
Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays.
Artim-Esen B, Pericleous C, Mackie I, Ripoll VM, Latchman D, Isenberg D, Rahman A, Ioannou Y, Giles I
Arthritis Res Ther 2015 Mar 7;17(1):47. doi: 10.1186/s13075-015-0568-7. PMID: 25890027Free PMC Article
Acute leukemia with megakaryocytic differentiation: a study of 12 cases identified immunocytochemically.
Huang MJ, Li CY, Nichols WL, Young JH, Katzmann JA
Blood 1984 Aug;64(2):427-39. PMID: 6378277

Supplemental Content

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