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Elevated bone scintigraphy uptake

MedGen UID:
1053664
Concept ID:
CN378374
Finding
Synonyms: Bone scan (scintigraphy): abnormally increased uptake; Increase bone scan uptake
 
HPO: HP:6001022

Definition

Bone scintigraph is performed with technetium 99m-labeled diphosphonates. The uptake of these radiopharmaceuticals depicts osteoblastic activity and regional blood flow to bone. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated bone scintigraphy uptake

Professional guidelines

PubMed

Li Z, Wu C, Wang C, Deng Z
Infection 2022 Oct;50(5):1217-1224. Epub 2022 Mar 14 doi: 10.1007/s15010-022-01795-x. PMID: 35288847
Hong JY, Kim HJ, Ko YH, Choi JY, Jung CW, Kim SJ, Kim WS
Acta Haematol 2014;131(1):18-27. Epub 2013 Sep 10 doi: 10.1159/000351060. PMID: 24021554
Chao M
Clin Oncol (R Coll Radiol) 2010 Aug;22(6):438-47. Epub 2010 Jun 18 doi: 10.1016/j.clon.2010.05.005. PMID: 20561773

Recent clinical studies

Etiology

Aimo A, Vergaro G, Castiglione V, Fabiani I, Barison A, Gentile F, Ferrari Chen YF, Giorgetti A, Genovesi D, Buda G, Franzini M, Piepoli M, Moscardini S, Rapezzi C, Fontana M, Passino C, Emdin M
Eur J Prev Cardiol 2024 Aug 22;31(11):1410-1417. doi: 10.1093/eurjpc/zwae093. PMID: 38456769
Devesa A, Lobo-González M, Martínez-Milla J, Oliva B, García-Lunar I, Mastrangelo A, España S, Sanz J, Mendiguren JM, Bueno H, Fuster JJ, Andrés V, Fernández-Ortiz A, Sancho D, Fernández-Friera L, Sanchez-Gonzalez J, Rossello X, Ibanez B, Fuster V
Eur Heart J 2022 May 14;43(19):1809-1828. Epub 2022 Mar 11 doi: 10.1093/eurheartj/ehac102. PMID: 35567559Free PMC Article
Qin C, Song Y, Liu X, Gai Y, Liu Q, Ruan W, Liu F, Hu F, Lan X
Eur J Nucl Med Mol Imaging 2022 Jan;49(2):709-720. Epub 2021 Jul 9 doi: 10.1007/s00259-021-05472-3. PMID: 34241652
Liu H, Wang J, Lang J, Zhang X
J Comput Assist Tomogr 2021 Sep-Oct 01;45(5):788-794. doi: 10.1097/RCT.0000000000001194. PMID: 34546683
Albano D, Bosio G, Bertoli M, Giubbini R, Bertagna F
J Neurooncol 2018 Feb;136(3):577-583. Epub 2017 Nov 17 doi: 10.1007/s11060-017-2686-3. PMID: 29147860

Diagnosis

Welleman OA, Schrama YC, Boiten HJ
JAMA 2023 Jul 3;330(1):76-77. doi: 10.1001/jama.2023.8977. PMID: 37347466
Liu X, Yan S, Qin X, Cheng K, Zheng J, Wu H, Wei Y, Yuan S
Skeletal Radiol 2023 Dec;52(12):2377-2386. Epub 2023 May 2 doi: 10.1007/s00256-023-04335-2. PMID: 37129613
Devesa A, Lobo-González M, Martínez-Milla J, Oliva B, García-Lunar I, Mastrangelo A, España S, Sanz J, Mendiguren JM, Bueno H, Fuster JJ, Andrés V, Fernández-Ortiz A, Sancho D, Fernández-Friera L, Sanchez-Gonzalez J, Rossello X, Ibanez B, Fuster V
Eur Heart J 2022 May 14;43(19):1809-1828. Epub 2022 Mar 11 doi: 10.1093/eurheartj/ehac102. PMID: 35567559Free PMC Article
Qin C, Song Y, Liu X, Gai Y, Liu Q, Ruan W, Liu F, Hu F, Lan X
Eur J Nucl Med Mol Imaging 2022 Jan;49(2):709-720. Epub 2021 Jul 9 doi: 10.1007/s00259-021-05472-3. PMID: 34241652
Hotta M, Minamimoto R, Yashima A, Nakano M, Yamashita H
Clin Nucl Med 2018 Nov;43(11):828-829. doi: 10.1097/RLU.0000000000002278. PMID: 30222681

Therapy

Devesa A, Lobo-González M, Martínez-Milla J, Oliva B, García-Lunar I, Mastrangelo A, España S, Sanz J, Mendiguren JM, Bueno H, Fuster JJ, Andrés V, Fernández-Ortiz A, Sancho D, Fernández-Friera L, Sanchez-Gonzalez J, Rossello X, Ibanez B, Fuster V
Eur Heart J 2022 May 14;43(19):1809-1828. Epub 2022 Mar 11 doi: 10.1093/eurheartj/ehac102. PMID: 35567559Free PMC Article
Boczar KE, Faller E, Zeng W, Wang J, Small GR, Corrales-Medina VF, deKemp RA, Ward NC, Beanlands RSB, MacPherson P, Dwivedi G
J Nucl Cardiol 2022 Dec;29(6):3057-3068. Epub 2021 Nov 24 doi: 10.1007/s12350-021-02830-4. PMID: 34820771
Iaremenko O, Petelytska L, Dyadyk O, Negria N, Fedkov D
Rheumatol Int 2020 Sep;40(9):1529-1536. Epub 2020 Jun 22 doi: 10.1007/s00296-020-04627-z. PMID: 32572610
Zunino A, Pitoia F, Faure E, Reyes A, Sala M, Sklate R, Ilera V, Califano I; Thyroid Department of Sociedad Argentina de Endocrinología y Metabolismo
Endocrine 2019 Sep;65(3):630-636. Epub 2019 Jul 20 doi: 10.1007/s12020-019-01991-0. PMID: 31327159
Chao M
Clin Oncol (R Coll Radiol) 2010 Aug;22(6):438-47. Epub 2010 Jun 18 doi: 10.1016/j.clon.2010.05.005. PMID: 20561773

Prognosis

Aimo A, Vergaro G, Castiglione V, Fabiani I, Barison A, Gentile F, Ferrari Chen YF, Giorgetti A, Genovesi D, Buda G, Franzini M, Piepoli M, Moscardini S, Rapezzi C, Fontana M, Passino C, Emdin M
Eur J Prev Cardiol 2024 Aug 22;31(11):1410-1417. doi: 10.1093/eurjpc/zwae093. PMID: 38456769
Kohno S, Furuta A, Arizono S, Tokunaga K, Nakao S, Tanabe M, Kataoka TR, Isoda H, Togashi K
Jpn J Radiol 2021 Sep;39(9):857-867. Epub 2021 May 22 doi: 10.1007/s11604-021-01130-8. PMID: 34021462Free PMC Article
Zunino A, Pitoia F, Faure E, Reyes A, Sala M, Sklate R, Ilera V, Califano I; Thyroid Department of Sociedad Argentina de Endocrinología y Metabolismo
Endocrine 2019 Sep;65(3):630-636. Epub 2019 Jul 20 doi: 10.1007/s12020-019-01991-0. PMID: 31327159
Ayubcha C, Hosoya H, Seraj SM, Zadeh MZ, Werner T, Alavi A
Hell J Nucl Med 2019 Jan-Apr;22(1):4-5. Epub 2019 Mar 7 doi: 10.1967/s002449910951. PMID: 30843002
Chao M
Clin Oncol (R Coll Radiol) 2010 Aug;22(6):438-47. Epub 2010 Jun 18 doi: 10.1016/j.clon.2010.05.005. PMID: 20561773

Clinical prediction guides

Aimo A, Vergaro G, Castiglione V, Fabiani I, Barison A, Gentile F, Ferrari Chen YF, Giorgetti A, Genovesi D, Buda G, Franzini M, Piepoli M, Moscardini S, Rapezzi C, Fontana M, Passino C, Emdin M
Eur J Prev Cardiol 2024 Aug 22;31(11):1410-1417. doi: 10.1093/eurjpc/zwae093. PMID: 38456769
Li Z, Wu C, Wang C, Deng Z
Infection 2022 Oct;50(5):1217-1224. Epub 2022 Mar 14 doi: 10.1007/s15010-022-01795-x. PMID: 35288847
Suomalainen O, Pilv J, Loimaala A, Mätzke S, Heliö T, Uusitalo V
J Nucl Cardiol 2022 Jun;29(3):1021-1029. Epub 2020 Oct 22 doi: 10.1007/s12350-020-02396-7. PMID: 33094472Free PMC Article
Yang S, Fu L, AbuduRxiti M, Wu J, Wang Q, Qin Y, Zou X, Li H
Nucl Med Commun 2020 May;41(5):477-484. doi: 10.1097/MNM.0000000000001170. PMID: 32168265
Chao M
Clin Oncol (R Coll Radiol) 2010 Aug;22(6):438-47. Epub 2010 Jun 18 doi: 10.1016/j.clon.2010.05.005. PMID: 20561773

Recent systematic reviews

Wang X, Gao J, Han S, Li Y
J Clin Neurosci 2019 May;63:234-239. Epub 2019 Jan 17 doi: 10.1016/j.jocn.2019.01.010. PMID: 30660478

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