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Allergy to penicillin

MedGen UID:
10626
Concept ID:
C0030824
Disease or Syndrome
Synonyms: Penicillin allergy; Penicillin Allergy
SNOMED CT: Penicillin allergy (91936005); Allergy to penicillin (91936005)

Definition

An allergy to Penicillin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAllergy to penicillin

Professional guidelines

PubMed

Green EA, Fogarty K, Ishmael FT
Med Clin North Am 2024 Jul;108(4):671-685. doi: 10.1016/j.mcna.2023.08.009. PMID: 38816110
Green EA, Fogarty K, Ishmael FT
Prim Care 2023 Jun;50(2):221-235. Epub 2023 Feb 26 doi: 10.1016/j.pop.2022.11.002. PMID: 37105603
Shenoy ES, Macy E, Rowe T, Blumenthal KG
JAMA 2019 Jan 15;321(2):188-199. doi: 10.1001/jama.2018.19283. PMID: 30644987

Recent clinical studies

Etiology

Felix MMR, Aun MV, Menezes UP, Queiroz GRES, Rodrigues AT, D'Onofrio-Silva AC, Perelló MI, Camelo-Nunes IC, Malaman MF
Einstein (Sao Paulo) 2021;19:eMD5703. Epub 2021 Apr 26 doi: 10.31744/einstein_journal/2021MD5703. PMID: 33909756Free PMC Article
Shaker M, McWilliams S, Greenhawt M
Curr Opin Pediatr 2020 Apr;32(2):321-327. doi: 10.1097/MOP.0000000000000879. PMID: 32068593
Shenoy ES, Macy E, Rowe T, Blumenthal KG
JAMA 2019 Jan 15;321(2):188-199. doi: 10.1001/jama.2018.19283. PMID: 30644987
Chang C, Mahmood MM, Teuber SS, Gershwin ME
Clin Rev Allergy Immunol 2012 Aug;43(1-2):84-97. doi: 10.1007/s12016-011-8279-6. PMID: 21789743
Madaan A, Li JT
Immunol Allergy Clin North Am 2004 Aug;24(3):463-76, vi-vii. doi: 10.1016/j.iac.2004.03.009. PMID: 15242721

Diagnosis

Green EA, Fogarty K, Ishmael FT
Med Clin North Am 2024 Jul;108(4):671-685. doi: 10.1016/j.mcna.2023.08.009. PMID: 38816110
Green EA, Fogarty K, Ishmael FT
Prim Care 2023 Jun;50(2):221-235. Epub 2023 Feb 26 doi: 10.1016/j.pop.2022.11.002. PMID: 37105603
Shenoy ES, Macy E, Rowe T, Blumenthal KG
JAMA 2019 Jan 15;321(2):188-199. doi: 10.1001/jama.2018.19283. PMID: 30644987
DeCastro A, Mims L, Hueston WJ
Prim Care 2014 Mar;41(1):47-61. doi: 10.1016/j.pop.2013.10.006. PMID: 24439880
Madaan A, Li JT
Immunol Allergy Clin North Am 2004 Aug;24(3):463-76, vi-vii. doi: 10.1016/j.iac.2004.03.009. PMID: 15242721

Therapy

Tang M, Nunna N, Zhong Q
J Pharm Pract 2025 Feb;38(1):168-179. Epub 2024 Aug 13 doi: 10.1177/08971900241273241. PMID: 39137364
Green EA, Fogarty K, Ishmael FT
Prim Care 2023 Jun;50(2):221-235. Epub 2023 Feb 26 doi: 10.1016/j.pop.2022.11.002. PMID: 37105603
Shenoy ES, Macy E, Rowe T, Blumenthal KG
JAMA 2019 Jan 15;321(2):188-199. doi: 10.1001/jama.2018.19283. PMID: 30644987
DeCastro A, Mims L, Hueston WJ
Prim Care 2014 Mar;41(1):47-61. doi: 10.1016/j.pop.2013.10.006. PMID: 24439880
Madaan A, Li JT
Immunol Allergy Clin North Am 2004 Aug;24(3):463-76, vi-vii. doi: 10.1016/j.iac.2004.03.009. PMID: 15242721

Prognosis

Roistacher DM, Heller JA, Ferraro NF, August M
J Oral Maxillofac Surg 2022 Jan;80(1):93-100. Epub 2021 Aug 19 doi: 10.1016/j.joms.2021.08.147. PMID: 34547269
DesBiens M, Scalia P, Ravikumar S, Glick A, Newton H, Erinne O, Riblet N
Am J Med 2020 Apr;133(4):452-462.e4. Epub 2019 Oct 21 doi: 10.1016/j.amjmed.2019.09.017. PMID: 31647915
Solensky R, Jacobs J, Lester M, Lieberman P, McCafferty F, Nilsson T, Park M, Schwarz G, Soong W, Wagelie-Steffen A, Wedner HJ, Weiss M, Windom H, Tonascia J, Yates KP, Mendelson LM, Wolfe J, Adkinson NF
J Allergy Clin Immunol Pract 2019 Jul-Aug;7(6):1876-1885.e3. Epub 2019 Mar 13 doi: 10.1016/j.jaip.2019.02.040. PMID: 30878711
Shenoy ES, Macy E, Rowe T, Blumenthal KG
JAMA 2019 Jan 15;321(2):188-199. doi: 10.1001/jama.2018.19283. PMID: 30644987
Ibáñez MD, Rodríguez Del Río P, Lasa EM, Joral A, Ruiz-Hornillos J, Muñoz C, Gómez Traseira C, Escudero C, Olaguibel Rivera JM, Garriga-Baraut T, González-de-Olano D, Rosado A, Sanchez-García S, Pérez Bustamante S, Padial Vilchez MA, Prieto Montaño P, Candón Morillo R, Macías Iglesia E, Feliú Vila A, Valbuena T, Lopez-Patiño A, Martorell A, Sastre J, Audícana MT; Penicillin Allergy in Children (APENIN) Task Force. Pediatric Allergy Committee, Spanish Society of Allergy and Clinical Immunology (SEAIC)
Ann Allergy Asthma Immunol 2018 Aug;121(2):235-244.e3. Epub 2018 May 25 doi: 10.1016/j.anai.2018.05.013. PMID: 29803713

Clinical prediction guides

Leung AKC, Lam JM, Barankin B, Leong KF, Hon KL
Curr Pediatr Rev 2024;21(1):2-17. doi: 10.2174/1573396320666230726145436. PMID: 37493159
Jonaitis P, Nyssen OP, Saracino IM, Fiorini G, Vaira D, Pérez-Aísa Á, Tepes B, Castro-Fernandez M, Pabón-Carrasco M, Keco-Huerga A, Voynovan I, Lucendo AJ, Lanas Á, Martínez-Domínguez SJ, Almajano EA, Rodrigo L, Vologzanina L, Brglez Jurecic N, Denkovski M, Bujanda L, Mahmudov U, Leja M, Lerang F, Babayeva G, Bordin DS, Gasbarrini A, Kupcinskas J, Gridnyev O, Rokkas T, Marcos-Pinto R, Phull PS, Smith SM, Tonkić A, Boltin D, Buzás GM, Šembera Š, Şimşek H, Matysiak-Budnik T, Milivojevic V, Marlicz W, Venerito M, Boyanova L, Doulberis M, Capelle LG, Cano-Català A, Moreira L, Mégraud F, O'Morain C, Gisbert JP, Jonaitis L; Hp-EuReg investigators
Sci Rep 2023 Oct 11;13(1):17235. doi: 10.1038/s41598-023-43287-4. PMID: 37821503Free PMC Article
Vyles D, Macy E
Expert Rev Anti Infect Ther 2019 Jun;17(6):429-435. Epub 2019 May 15 doi: 10.1080/14787210.2019.1617132. PMID: 31067139
Shenoy ES, Macy E, Rowe T, Blumenthal KG
JAMA 2019 Jan 15;321(2):188-199. doi: 10.1001/jama.2018.19283. PMID: 30644987
Chang C, Mahmood MM, Teuber SS, Gershwin ME
Clin Rev Allergy Immunol 2012 Aug;43(1-2):84-97. doi: 10.1007/s12016-011-8279-6. PMID: 21789743

Recent systematic reviews

Edibam NR, Lorenzo-Pouso AI, Caponio VCA
Clin Oral Implants Res 2023 Jul;34(7):651-661. Epub 2023 Apr 27 doi: 10.1111/clr.14073. PMID: 37102260
Rodríguez-Alarcón A, Barceló-Vidal J, Echeverría-Esnal D, Sorli L, Güerri-Fernández R, Ramis Fernández SM, Benitez-Cano A, Sendra E, López Montesinos I, Membrilla-Fernández E, Ferrández O, Adalia R, Horcajada JP, Escolano F, Gómez-Zorrilla S, Grau S; , on behalf of PROA-PSMAR group.
Expert Rev Anti Infect Ther 2022 Nov;20(11):1491-1500. Epub 2022 Sep 12 doi: 10.1080/14787210.2022.2122443. PMID: 36069242
DesBiens M, Scalia P, Ravikumar S, Glick A, Newton H, Erinne O, Riblet N
Am J Med 2020 Apr;133(4):452-462.e4. Epub 2019 Oct 21 doi: 10.1016/j.amjmed.2019.09.017. PMID: 31647915
Wang L, Cui X, Cheng L, Yuan Q, Li T, Li Y, Deng S, Shang H, Bian Z
J Evid Based Med 2010 Aug;3(3):168-76. doi: 10.1111/j.1756-5391.2010.01091.x. PMID: 21349062
Wang L, Cheng L, Yuan Q, Cui X, Shang H, Zhang B, Li Y
J Evid Based Med 2010 Feb;3(1):18-26. Epub 2010 Feb 17 doi: 10.1111/j.1756-5391.2010.01067.x. PMID: 21349036

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