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Deformity of spine

MedGen UID:
107896
•Concept ID:
C0575157
•
Anatomical Abnormality
Synonyms: Spinal deformities; Spinal deformity
SNOMED CT: Deformity of spine (298380006)

Definition

A congenital or acquired deformity of the spine. Representative examples include scoliosis, kyphosis, and sagittal imbalance. [from NCI]

Professional guidelines

PubMed

Treatment of spine deformity in neuromuscular diseases.
Maitra S, Roberto RF, McDonald CM, Gupta MC
Phys Med Rehabil Clin N Am 2012 Nov;23(4):869-83. doi: 10.1016/j.pmr.2012.08.009. PMID: 23137742
Clinical experience with the use of low molecular weight heparin in orthopaedic treatment of paediatric patients.
Latalski M, Fatyga M, Misztal M, Gregosiewicz A, Danilewicz Bromberek A
Ortop Traumatol Rehabil 2012 Jul-Aug;14(4):329-33. doi: 10.5604/15093492.1005092. PMID: 23043055
Fusionless instrumentation systems for congenital scoliosis: expandable spinal rods and vertical expandable prosthetic titanium rib in the management of congenital spine deformities in the growing child.
Yazici M, Emans J
Spine (Phila Pa 1976) 2009 Aug 1;34(17):1800-7. doi: 10.1097/BRS.0b013e3181978ec9. PMID: 19644331

Recent clinical studies

Etiology

Changes in circulating cell-free nuclear DNA and mitochondrial DNA of patients with adolescent idiopathic scoliosis.
Li J, Wang L, Yang G, Wang Y, Guo C, Liu S, Gao Q, Zhang H
BMC Musculoskelet Disord 2019 Oct 25;20(1):479. doi: 10.1186/s12891-019-2869-5. PMID: 31653238Free PMC Article
Diagnostic value of ELISPOT technique for osteoarticular tuberculosis.
Wu X, Ma Y, Li D, Yang Y, Liang Y, Xue H, Zhang J
Clin Lab 2014;60(11):1865-70. doi: 10.7754/clin.lab.2014.140110. PMID: 25648028
Scoliosis on pulmonary function.
Ran H, Zhi-hong W, Jiang-na H
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2011 Feb;33(1):102-6. doi: 10.3881/j.issn.1000-503X.2011.01.023. PMID: 21375948
High selenium may be a risk factor of adolescent idiopathic scoliosis.
Yang Z, Xie Y, Chen J, Zhang D, Yang C, Li M
Med Hypotheses 2010 Jul;75(1):126-7. Epub 2010 Feb 26 doi: 10.1016/j.mehy.2010.02.006. PMID: 20189316
Transpedicular decancellation closed wedge vertebral osteotomy for treatment of fixed flexion deformity of spine in ankylosing spondylitis.
Thiranont N, Netrawichien P
Spine (Phila Pa 1976) 1993 Dec;18(16):2517-22. doi: 10.1097/00007632-199312000-00023. PMID: 8303457

Diagnosis

Changes in circulating cell-free nuclear DNA and mitochondrial DNA of patients with adolescent idiopathic scoliosis.
Li J, Wang L, Yang G, Wang Y, Guo C, Liu S, Gao Q, Zhang H
BMC Musculoskelet Disord 2019 Oct 25;20(1):479. doi: 10.1186/s12891-019-2869-5. PMID: 31653238Free PMC Article
Diagnostic value of ELISPOT technique for osteoarticular tuberculosis.
Wu X, Ma Y, Li D, Yang Y, Liang Y, Xue H, Zhang J
Clin Lab 2014;60(11):1865-70. doi: 10.7754/clin.lab.2014.140110. PMID: 25648028
Single vertebra tuberculosis presenting with solitary localized osteolytic lesion in young adult lumbar spines.
Zhen P, Li XS, Lu H
Orthop Surg 2013 May;5(2):105-11. doi: 10.1111/os.12037. PMID: 23658045Free PMC Article
Surgical treatment of congenital vertebral displacement Type A in the sagittal plane only: a retrospective study involving eleven cases.
Zarzycki D, Rymarczyk A, Bakalarek B, Kalicinski M, Winiarski A
Spine (Phila Pa 1976) 2002 Jan 1;27(1):72-7. doi: 10.1097/00007632-200201010-00017. PMID: 11805639

Therapy

High selenium may be a risk factor of adolescent idiopathic scoliosis.
Yang Z, Xie Y, Chen J, Zhang D, Yang C, Li M
Med Hypotheses 2010 Jul;75(1):126-7. Epub 2010 Feb 26 doi: 10.1016/j.mehy.2010.02.006. PMID: 20189316
Surgical treatment of congenital vertebral displacement Type A in the sagittal plane only: a retrospective study involving eleven cases.
Zarzycki D, Rymarczyk A, Bakalarek B, Kalicinski M, Winiarski A
Spine (Phila Pa 1976) 2002 Jan 1;27(1):72-7. doi: 10.1097/00007632-200201010-00017. PMID: 11805639

Prognosis

Changes in circulating cell-free nuclear DNA and mitochondrial DNA of patients with adolescent idiopathic scoliosis.
Li J, Wang L, Yang G, Wang Y, Guo C, Liu S, Gao Q, Zhang H
BMC Musculoskelet Disord 2019 Oct 25;20(1):479. doi: 10.1186/s12891-019-2869-5. PMID: 31653238Free PMC Article
Diagnostic value of ELISPOT technique for osteoarticular tuberculosis.
Wu X, Ma Y, Li D, Yang Y, Liang Y, Xue H, Zhang J
Clin Lab 2014;60(11):1865-70. doi: 10.7754/clin.lab.2014.140110. PMID: 25648028
Surgical treatment of congenital vertebral displacement Type A in the sagittal plane only: a retrospective study involving eleven cases.
Zarzycki D, Rymarczyk A, Bakalarek B, Kalicinski M, Winiarski A
Spine (Phila Pa 1976) 2002 Jan 1;27(1):72-7. doi: 10.1097/00007632-200201010-00017. PMID: 11805639
Transpedicular decancellation closed wedge vertebral osteotomy for treatment of fixed flexion deformity of spine in ankylosing spondylitis.
Thiranont N, Netrawichien P
Spine (Phila Pa 1976) 1993 Dec;18(16):2517-22. doi: 10.1097/00007632-199312000-00023. PMID: 8303457

Clinical prediction guides

Acute Effects of Self-Correction on Spine Deviation and Balance in Adolescent Girls with Idiopathic Scoliosis.
Marin L, Lovecchio N, Pedrotti L, Manzoni F, Febbi M, Albanese I, Patanè P, Carnevale Pellino V, Vandoni M
Sensors (Basel) 2022 Feb 28;22(5) doi: 10.3390/s22051883. PMID: 35271030Free PMC Article
Changes in circulating cell-free nuclear DNA and mitochondrial DNA of patients with adolescent idiopathic scoliosis.
Li J, Wang L, Yang G, Wang Y, Guo C, Liu S, Gao Q, Zhang H
BMC Musculoskelet Disord 2019 Oct 25;20(1):479. doi: 10.1186/s12891-019-2869-5. PMID: 31653238Free PMC Article
Diagnostic value of ELISPOT technique for osteoarticular tuberculosis.
Wu X, Ma Y, Li D, Yang Y, Liang Y, Xue H, Zhang J
Clin Lab 2014;60(11):1865-70. doi: 10.7754/clin.lab.2014.140110. PMID: 25648028
Surgical treatment of congenital vertebral displacement Type A in the sagittal plane only: a retrospective study involving eleven cases.
Zarzycki D, Rymarczyk A, Bakalarek B, Kalicinski M, Winiarski A
Spine (Phila Pa 1976) 2002 Jan 1;27(1):72-7. doi: 10.1097/00007632-200201010-00017. PMID: 11805639

Recent systematic reviews

Scoliosis on pulmonary function.
Ran H, Zhi-hong W, Jiang-na H
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2011 Feb;33(1):102-6. doi: 10.3881/j.issn.1000-503X.2011.01.023. PMID: 21375948

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