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Rectal pain

MedGen UID:
11149
•Concept ID:
C0034886
•
Sign or Symptom
Synonyms: Pain in rectum; Proctalgia; Rectal Pain; Rectalgia
SNOMED CT: Rectal pain (77880009); Pain in rectum (77880009); Proctalgia (77880009); Rectalgia (77880009)

Definition

Pain in the rectal area. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRectal pain

Professional guidelines

PubMed

Colorectal Surgery Review for Primary Care Providers.
Hegde R, Trombold JM, Dominguez JM
Mo Med 2020 Mar-Apr;117(2):154-158. PMID: 32308242Free PMC Article
Benign Anorectal Conditions: Evaluation and Management.
Cohee MW, Hurff A, Gazewood JD
Am Fam Physician 2020 Jan 1;101(1):24-33. PMID: 31894930
Crohn's Disease: Diagnosis and Management.
Veauthier B, Hornecker JR
Am Fam Physician 2018 Dec 1;98(11):661-669. PMID: 30485038

Recent clinical studies

Etiology

Botulinum toxin injection in vulva and vagina. Evidence from a literature systematic review.
Parenti M, Degliuomini RS, Cosmi E, Vitagliano A, Fasola E, Origoni M, Salvatore S, Buzzaccarini G
Eur J Obstet Gynecol Reprod Biol 2023 Dec;291:178-189. Epub 2023 Oct 27 doi: 10.1016/j.ejogrb.2023.10.028. PMID: 38353087
Factors influencing rectal hypersensitivity in irritable bowel syndrome: A systematic review and meta-analysis.
Roberts C, Albusoda A, Farmer AD, Aziz Q
Neurogastroenterol Motil 2023 Apr;35(4):e14515. Epub 2022 Dec 26 doi: 10.1111/nmo.14515. PMID: 36573039
Monkeypox.
Mitjà O, Ogoina D, Titanji BK, Galvan C, Muyembe JJ, Marks M, Orkin CM
Lancet 2023 Jan 7;401(10370):60-74. Epub 2022 Nov 17 doi: 10.1016/S0140-6736(22)02075-X. PMID: 36403582Free PMC Article
Incidence and risk factors for rectal pain after laparoscopic rectal cancer surgery.
Lee JY, Kim HC, Huh JW, Sim WS, Lim HY, Lee EK, Park HG, Bang YJ
J Int Med Res 2017 Apr;45(2):781-791. Epub 2017 Mar 16 doi: 10.1177/0300060517693421. PMID: 28415928Free PMC Article
Hydrogel Spacer Prospective Multicenter Randomized Controlled Pivotal Trial: Dosimetric and Clinical Effects of Perirectal Spacer Application in Men Undergoing Prostate Image Guided Intensity Modulated Radiation Therapy.
Mariados N, Sylvester J, Shah D, Karsh L, Hudes R, Beyer D, Kurtzman S, Bogart J, Hsi RA, Kos M, Ellis R, Logsdon M, Zimberg S, Forsythe K, Zhang H, Soffen E, Francke P, Mantz C, Rossi P, DeWeese T, Hamstra DA, Bosch W, Gay H, Michalski J
Int J Radiat Oncol Biol Phys 2015 Aug 1;92(5):971-977. Epub 2015 Apr 23 doi: 10.1016/j.ijrobp.2015.04.030. PMID: 26054865

Diagnosis

Monkeypox.
Mitjà O, Ogoina D, Titanji BK, Galvan C, Muyembe JJ, Marks M, Orkin CM
Lancet 2023 Jan 7;401(10370):60-74. Epub 2022 Nov 17 doi: 10.1016/S0140-6736(22)02075-X. PMID: 36403582Free PMC Article
Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series.
Patel A, Bilinska J, Tam JCH, Da Silva Fontoura D, Mason CY, Daunt A, Snell LB, Murphy J, Potter J, Tuudah C, Sundramoorthi R, Abeywickrema M, Pley C, Naidu V, Nebbia G, Aarons E, Botgros A, Douthwaite ST, van Nispen Tot Pannerden C, Winslow H, Brown A, Chilton D, Nori A
BMJ 2022 Jul 28;378:e072410. doi: 10.1136/bmj-2022-072410. PMID: 35902115Free PMC Article
Colorectal Surgery Review for Primary Care Providers.
Hegde R, Trombold JM, Dominguez JM
Mo Med 2020 Mar-Apr;117(2):154-158. PMID: 32308242Free PMC Article
Benign Anorectal Conditions: Evaluation and Management.
Cohee MW, Hurff A, Gazewood JD
Am Fam Physician 2020 Jan 1;101(1):24-33. PMID: 31894930
Anorectal disorders.
Janicke DM, Pundt MR
Emerg Med Clin North Am 1996 Nov;14(4):757-88. doi: 10.1016/s0733-8627(05)70278-9. PMID: 8921768

Therapy

Botulinum toxin injection in vulva and vagina. Evidence from a literature systematic review.
Parenti M, Degliuomini RS, Cosmi E, Vitagliano A, Fasola E, Origoni M, Salvatore S, Buzzaccarini G
Eur J Obstet Gynecol Reprod Biol 2023 Dec;291:178-189. Epub 2023 Oct 27 doi: 10.1016/j.ejogrb.2023.10.028. PMID: 38353087
Prostate Cancer Screening.
Mulhem E, Fulbright N, Duncan N
Am Fam Physician 2015 Oct 15;92(8):683-8. PMID: 26554408
Hydrogel Spacer Prospective Multicenter Randomized Controlled Pivotal Trial: Dosimetric and Clinical Effects of Perirectal Spacer Application in Men Undergoing Prostate Image Guided Intensity Modulated Radiation Therapy.
Mariados N, Sylvester J, Shah D, Karsh L, Hudes R, Beyer D, Kurtzman S, Bogart J, Hsi RA, Kos M, Ellis R, Logsdon M, Zimberg S, Forsythe K, Zhang H, Soffen E, Francke P, Mantz C, Rossi P, DeWeese T, Hamstra DA, Bosch W, Gay H, Michalski J
Int J Radiat Oncol Biol Phys 2015 Aug 1;92(5):971-977. Epub 2015 Apr 23 doi: 10.1016/j.ijrobp.2015.04.030. PMID: 26054865
Diagnosis and treatment of ulcerative proctitis.
Regueiro MD
J Clin Gastroenterol 2004 Oct;38(9):733-40. doi: 10.1097/01.mcg.0000139178.33502.a3. PMID: 15365396
Biofeedback therapy in the colon and rectal practice.
Jorge JM, Habr-Gama A, Wexner SD
Appl Psychophysiol Biofeedback 2003 Mar;28(1):47-61. doi: 10.1023/a:1022316900628. PMID: 12737096

Prognosis

Recent Developments in On-Demand Voiding Therapies.
Thor KB, Marson L, Katofiasc MA, Ricca DJ, Burgard EC
J Pharmacol Exp Ther 2024 Aug 19;390(3):302-317. doi: 10.1124/jpet.123.002073. PMID: 38641354Free PMC Article
Factors influencing rectal hypersensitivity in irritable bowel syndrome: A systematic review and meta-analysis.
Roberts C, Albusoda A, Farmer AD, Aziz Q
Neurogastroenterol Motil 2023 Apr;35(4):e14515. Epub 2022 Dec 26 doi: 10.1111/nmo.14515. PMID: 36573039
Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series.
Patel A, Bilinska J, Tam JCH, Da Silva Fontoura D, Mason CY, Daunt A, Snell LB, Murphy J, Potter J, Tuudah C, Sundramoorthi R, Abeywickrema M, Pley C, Naidu V, Nebbia G, Aarons E, Botgros A, Douthwaite ST, van Nispen Tot Pannerden C, Winslow H, Brown A, Chilton D, Nori A
BMJ 2022 Jul 28;378:e072410. doi: 10.1136/bmj-2022-072410. PMID: 35902115Free PMC Article
Incidence and risk factors for rectal pain after laparoscopic rectal cancer surgery.
Lee JY, Kim HC, Huh JW, Sim WS, Lim HY, Lee EK, Park HG, Bang YJ
J Int Med Res 2017 Apr;45(2):781-791. Epub 2017 Mar 16 doi: 10.1177/0300060517693421. PMID: 28415928Free PMC Article
Efficacy and safety of PPC-5650 on experimental rectal pain in patients with irritable bowel syndrome.
Nielsen LM, Olesen AE, Andresen T, Simrén M, Törnblom H, Drewes AM
Basic Clin Pharmacol Toxicol 2015 Feb;116(2):140-5. Epub 2014 Sep 8 doi: 10.1111/bcpt.12294. PMID: 25052366

Clinical prediction guides

Recent Developments in On-Demand Voiding Therapies.
Thor KB, Marson L, Katofiasc MA, Ricca DJ, Burgard EC
J Pharmacol Exp Ther 2024 Aug 19;390(3):302-317. doi: 10.1124/jpet.123.002073. PMID: 38641354Free PMC Article
Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series.
Patel A, Bilinska J, Tam JCH, Da Silva Fontoura D, Mason CY, Daunt A, Snell LB, Murphy J, Potter J, Tuudah C, Sundramoorthi R, Abeywickrema M, Pley C, Naidu V, Nebbia G, Aarons E, Botgros A, Douthwaite ST, van Nispen Tot Pannerden C, Winslow H, Brown A, Chilton D, Nori A
BMJ 2022 Jul 28;378:e072410. doi: 10.1136/bmj-2022-072410. PMID: 35902115Free PMC Article
Incidence and risk factors for rectal pain after laparoscopic rectal cancer surgery.
Lee JY, Kim HC, Huh JW, Sim WS, Lim HY, Lee EK, Park HG, Bang YJ
J Int Med Res 2017 Apr;45(2):781-791. Epub 2017 Mar 16 doi: 10.1177/0300060517693421. PMID: 28415928Free PMC Article
Prostate Cancer Screening.
Mulhem E, Fulbright N, Duncan N
Am Fam Physician 2015 Oct 15;92(8):683-8. PMID: 26554408
Hydrogel Spacer Prospective Multicenter Randomized Controlled Pivotal Trial: Dosimetric and Clinical Effects of Perirectal Spacer Application in Men Undergoing Prostate Image Guided Intensity Modulated Radiation Therapy.
Mariados N, Sylvester J, Shah D, Karsh L, Hudes R, Beyer D, Kurtzman S, Bogart J, Hsi RA, Kos M, Ellis R, Logsdon M, Zimberg S, Forsythe K, Zhang H, Soffen E, Francke P, Mantz C, Rossi P, DeWeese T, Hamstra DA, Bosch W, Gay H, Michalski J
Int J Radiat Oncol Biol Phys 2015 Aug 1;92(5):971-977. Epub 2015 Apr 23 doi: 10.1016/j.ijrobp.2015.04.030. PMID: 26054865

Recent systematic reviews

Mpox gastrointestinal manifestations: a systematic review.
Ramakrishnan R, Shenoy A, Madhavan R, Meyer D
BMJ Open Gastroenterol 2024 Jan 6;11(1) doi: 10.1136/bmjgast-2023-001266. PMID: 38184298Free PMC Article
Botulinum toxin injection in vulva and vagina. Evidence from a literature systematic review.
Parenti M, Degliuomini RS, Cosmi E, Vitagliano A, Fasola E, Origoni M, Salvatore S, Buzzaccarini G
Eur J Obstet Gynecol Reprod Biol 2023 Dec;291:178-189. Epub 2023 Oct 27 doi: 10.1016/j.ejogrb.2023.10.028. PMID: 38353087
Clinical Features, Antiviral Treatment, and Patient Outcomes: A Systematic Review and Comparative Analysis of the Previous and the 2022 Mpox Outbreaks.
Li P, Li J, Ayada I, Avan A, Zheng Q, Peppelenbosch MP, de Vries AC, Pan Q
J Infect Dis 2023 Aug 16;228(4):391-401. doi: 10.1093/infdis/jiad034. PMID: 36735342Free PMC Article
Factors influencing rectal hypersensitivity in irritable bowel syndrome: A systematic review and meta-analysis.
Roberts C, Albusoda A, Farmer AD, Aziz Q
Neurogastroenterol Motil 2023 Apr;35(4):e14515. Epub 2022 Dec 26 doi: 10.1111/nmo.14515. PMID: 36573039
Management of Malignant Rectal Pain and Tenesmus: A Systematic Review.
Mueller K, Karimuddin AA, Metcalf C, Woo A, Lefresne S
J Palliat Med 2020 Jul;23(7):964-971. Epub 2019 Nov 4 doi: 10.1089/jpm.2019.0139. PMID: 31682188

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