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Acute bronchiolitis

MedGen UID:
113
•Concept ID:
C0001311
•
Disease or Syndrome
Synonyms: Acute Bronchiolitis; acute bronchiolitis; acute Bronchiolitis; Acute capillary bronchiolitis; acute capillary bronchiolitis; Capillary pneumonia; capillary pneumonia
SNOMED CT: Acute bronchiolitis (5505005); Capillary pneumonia (5505005); Acute capillary bronchiolitis (5505005)
 
Monarch Initiative: MONDO:0020680

Definition

Acute inflammation of the bronchioles usually caused by the respiratory syncytial virus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute bronchiolitis

Professional guidelines

PubMed

Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children.
Zhang XL, Zhang X, Hua W, Xie ZD, Liu HM, Zhang HL, Chen BQ, Chen Y, Sun X, Xu Y, Shu SN, Zhao SY, Shang YX, Cao L, Jia YH, Lin LN, Li J, Hao CL, Dong XY, Lin DJ, Xu HM, Zhao DY, Zeng M, Chen ZM, Huang LS
World J Pediatr 2024 Jan;20(1):11-25. Epub 2023 Dec 8 doi: 10.1007/s12519-023-00777-9. PMID: 38064012Free PMC Article
UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Manti S, Staiano A, Orfeo L, Midulla F, Marseglia GL, Ghizzi C, Zampogna S, Carnielli VP, Favilli S, Ruggieri M, Perri D, Di Mauro G, Gattinara GC, D'Avino A, Becherucci P, Prete A, Zampino G, Lanari M, Biban P, Manzoni P, Esposito S, Corsello G, Baraldi E
Ital J Pediatr 2023 Feb 10;49(1):19. doi: 10.1186/s13052-022-01392-6. PMID: 36765418Free PMC Article
Acute bronchiolitis: assessment and management in the emergency department.
Joseph MM, Edwards A
Pediatr Emerg Med Pract 2019 Oct;16(10):1-24. Epub 2019 Oct 2 PMID: 31557431

Curated

UK NICE Guideline NG9, Bronchiolitis in children: diagnosis and management, 2021

Recent clinical studies

Etiology

Nebulised hypertonic saline solution for acute bronchiolitis in infants.
Zhang L, Mendoza-Sassi RA, Wainwright CE, Aregbesola A, Klassen TP
Cochrane Database Syst Rev 2023 Apr 4;4(4):CD006458. doi: 10.1002/14651858.CD006458.pub5. PMID: 37014057Free PMC Article
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué-Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. PMID: 37010196Free PMC Article
UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Manti S, Staiano A, Orfeo L, Midulla F, Marseglia GL, Ghizzi C, Zampogna S, Carnielli VP, Favilli S, Ruggieri M, Perri D, Di Mauro G, Gattinara GC, D'Avino A, Becherucci P, Prete A, Zampino G, Lanari M, Biban P, Manzoni P, Esposito S, Corsello G, Baraldi E
Ital J Pediatr 2023 Feb 10;49(1):19. doi: 10.1186/s13052-022-01392-6. PMID: 36765418Free PMC Article
Respiratory Syncytial Virus is the Most Common Causative Agent of Viral Bronchiolitis in Young Children: An Updated Review.
Hon KL, Leung AKC, Wong AHC, Dudi A, Leung KKY
Curr Pediatr Rev 2023;19(2):139-149. doi: 10.2174/1573396318666220810161945. PMID: 35950255
Effectiveness of airway clearance techniques in children hospitalized with acute bronchiolitis.
Van Ginderdeuren F, Vandenplas Y, Deneyer M, Vanlaethem S, Buyl R, Kerckhofs E
Pediatr Pulmonol 2017 Feb;52(2):225-231. Epub 2016 Jun 2 doi: 10.1002/ppul.23495. PMID: 27254132

Diagnosis

UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Manti S, Staiano A, Orfeo L, Midulla F, Marseglia GL, Ghizzi C, Zampogna S, Carnielli VP, Favilli S, Ruggieri M, Perri D, Di Mauro G, Gattinara GC, D'Avino A, Becherucci P, Prete A, Zampino G, Lanari M, Biban P, Manzoni P, Esposito S, Corsello G, Baraldi E
Ital J Pediatr 2023 Feb 10;49(1):19. doi: 10.1186/s13052-022-01392-6. PMID: 36765418Free PMC Article
Respiratory Syncytial Virus is the Most Common Causative Agent of Viral Bronchiolitis in Young Children: An Updated Review.
Hon KL, Leung AKC, Wong AHC, Dudi A, Leung KKY
Curr Pediatr Rev 2023;19(2):139-149. doi: 10.2174/1573396318666220810161945. PMID: 35950255
Acute bronchiolitis: assessment and management in the emergency department.
Joseph MM, Edwards A
Pediatr Emerg Med Pract 2019 Oct;16(10):1-24. Epub 2019 Oct 2 PMID: 31557431
Respiratory syncytial virus--a comprehensive review.
Borchers AT, Chang C, Gershwin ME, Gershwin LJ
Clin Rev Allergy Immunol 2013 Dec;45(3):331-79. doi: 10.1007/s12016-013-8368-9. PMID: 23575961Free PMC Article
Acute bronchiolitis.
Bush A, Thomson AH
BMJ 2007 Nov 17;335(7628):1037-41. doi: 10.1136/bmj.39374.600081.AD. PMID: 18007004Free PMC Article

Therapy

Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué-Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. PMID: 37010196Free PMC Article
UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.
Manti S, Staiano A, Orfeo L, Midulla F, Marseglia GL, Ghizzi C, Zampogna S, Carnielli VP, Favilli S, Ruggieri M, Perri D, Di Mauro G, Gattinara GC, D'Avino A, Becherucci P, Prete A, Zampino G, Lanari M, Biban P, Manzoni P, Esposito S, Corsello G, Baraldi E
Ital J Pediatr 2023 Feb 10;49(1):19. doi: 10.1186/s13052-022-01392-6. PMID: 36765418Free PMC Article
Respiratory Syncytial Virus is the Most Common Causative Agent of Viral Bronchiolitis in Young Children: An Updated Review.
Hon KL, Leung AKC, Wong AHC, Dudi A, Leung KKY
Curr Pediatr Rev 2023;19(2):139-149. doi: 10.2174/1573396318666220810161945. PMID: 35950255
Acute bronchiolitis: assessment and management in the emergency department.
Joseph MM, Edwards A
Pediatr Emerg Med Pract 2019 Oct;16(10):1-24. Epub 2019 Oct 2 PMID: 31557431
Effectiveness of airway clearance techniques in children hospitalized with acute bronchiolitis.
Van Ginderdeuren F, Vandenplas Y, Deneyer M, Vanlaethem S, Buyl R, Kerckhofs E
Pediatr Pulmonol 2017 Feb;52(2):225-231. Epub 2016 Jun 2 doi: 10.1002/ppul.23495. PMID: 27254132

Prognosis

Comparison of severity scales for acute bronchiolitis in real clinical practice.
Granda E, Urbano M, Andrés P, Corchete M, Cano A, Velasco R
Eur J Pediatr 2023 Apr;182(4):1619-1626. Epub 2023 Jan 27 doi: 10.1007/s00431-023-04840-5. PMID: 36702906
Reduction in the incidence of acute bronchiolitis and related hospital admissions during the COVID-19 pandemic.
Montejo M, Sánchez A, Paniagua N, Saiz-Hernando C, Benito J
An Pediatr (Engl Ed) 2022 Jun;96(6):537-539. Epub 2022 Mar 11 doi: 10.1016/j.anpede.2022.03.003. PMID: 35637146Free PMC Article
Bronchiolitis: update 2001.
Schlesinger C, Koss MN
Curr Opin Pulm Med 2002 Mar;8(2):112-6. doi: 10.1097/00063198-200203000-00006. PMID: 11845006
Acute bronchiolitis in infancy: treatment and prognosis.
Milner AD, Murray M
Thorax 1989 Jan;44(1):1-5. doi: 10.1136/thx.44.1.1. PMID: 2648640Free PMC Article
Acute bronchiolitis and the asthmatic child.
Hyde JS, Saed AM
J Asthma Res 1966 Dec;4(2):137-54. doi: 10.3109/02770906609100534. PMID: 5959132

Clinical prediction guides

Nebulised hypertonic saline solution for acute bronchiolitis in infants.
Zhang L, Mendoza-Sassi RA, Wainwright CE, Aregbesola A, Klassen TP
Cochrane Database Syst Rev 2023 Apr 4;4(4):CD006458. doi: 10.1002/14651858.CD006458.pub5. PMID: 37014057Free PMC Article
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué-Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. PMID: 37010196Free PMC Article
Comparison of severity scales for acute bronchiolitis in real clinical practice.
Granda E, Urbano M, Andrés P, Corchete M, Cano A, Velasco R
Eur J Pediatr 2023 Apr;182(4):1619-1626. Epub 2023 Jan 27 doi: 10.1007/s00431-023-04840-5. PMID: 36702906
Respiratory Syncytial Virus is the Most Common Causative Agent of Viral Bronchiolitis in Young Children: An Updated Review.
Hon KL, Leung AKC, Wong AHC, Dudi A, Leung KKY
Curr Pediatr Rev 2023;19(2):139-149. doi: 10.2174/1573396318666220810161945. PMID: 35950255
Bronchodilators for bronchiolitis.
Gadomski AM, Scribani MB
Cochrane Database Syst Rev 2014 Jun 17;2014(6):CD001266. doi: 10.1002/14651858.CD001266.pub4. PMID: 24937099Free PMC Article

Recent systematic reviews

Nebulised hypertonic saline solution for acute bronchiolitis in infants.
Zhang L, Mendoza-Sassi RA, Wainwright CE, Aregbesola A, Klassen TP
Cochrane Database Syst Rev 2023 Apr 4;4(4):CD006458. doi: 10.1002/14651858.CD006458.pub5. PMID: 37014057Free PMC Article
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué-Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6. PMID: 37010196Free PMC Article
Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old.
Roqué i Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J
Cochrane Database Syst Rev 2016 Feb 1;2(2):CD004873. doi: 10.1002/14651858.CD004873.pub5. PMID: 26833493Free PMC Article
Bronchodilators for bronchiolitis.
Gadomski AM, Scribani MB
Cochrane Database Syst Rev 2014 Jun 17;2014(6):CD001266. doi: 10.1002/14651858.CD001266.pub4. PMID: 24937099Free PMC Article
Bronchodilators for bronchiolitis.
Gadomski AM, Brower M
Cochrane Database Syst Rev 2010 Dec 8;(12):CD001266. doi: 10.1002/14651858.CD001266.pub2. PMID: 21154348

Supplemental Content

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    Clinical resources

    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2021
      UK NICE Guideline NG9, Bronchiolitis in children: diagnosis and management, 2021

    Consumer resources

    Reviews

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    • PMC Articles
      Related information in PubMed Central Links
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