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Schizophreniform disorder

MedGen UID:
11336
Concept ID:
C0036358
Mental or Behavioral Dysfunction
Synonyms: Disorder, Schizophreniform; Disorders, Schizophreniform; Schizophreniform Disorder; Schizophreniform Disorders
SNOMED CT: Schizophreniform disorder (88975006)
 
Monarch Initiative: MONDO:0001265

Definition

A disorder that differs from schizophrenia specifically in total duration (schizophreniform disorder lasts at least 1 month but less than 6 months whereas schizophrenia lasts at least 6 months); schizophreniform disorder also typically causes less impairment in the individual''s social and occupational functioning. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSchizophreniform disorder

Professional guidelines

PubMed

Singh SB, Bhattarai Y, Kafle R, Panta M, Tiwari A, Ayubcha C, Werner TJ, Alavi A, Revheim ME
PET Clin 2025 Jan;20(1):11-24. Epub 2024 Oct 29 doi: 10.1016/j.cpet.2024.09.005. PMID: 39477720
Wajima Z
J Nippon Med Sch 2019;86(2):70-80. doi: 10.1272/jnms.JNMS.2019_86-202. PMID: 31130568
Arunpongpaisal S, Ahmed I, Aqeel N, Suchat P
Cochrane Database Syst Rev 2003;(2):CD004162. doi: 10.1002/14651858.CD004162. PMID: 12804499

Recent clinical studies

Etiology

Teixeira da Cunha I, Silveira C, Freitas A, Gonçalves Pinho M
Acta Med Port 2024 Dec 2;37(12):823-830. Epub 2024 Sep 6 doi: 10.20344/amp.21714. PMID: 39239882
Maia-de-Oliveira JP, Kandratavicius L, Nunes EA, Machado-de-Sousa JP, Hallak JE, Dursun SM
Curr Med Chem 2016;23(24):2680-2691. doi: 10.2174/0929867323666160721144549. PMID: 27450675
Hay A, Byers A, Sereno M, Basra MK, Dutta S
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD011458. doi: 10.1002/14651858.CD011458.pub2. PMID: 26599405Free PMC Article
Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, Gheorghe MD, Rybakowski JK, Galderisi S, Libiger J, Hummer M, Dollfus S, López-Ibor JJ, Hranov LG, Gaebel W, Peuskens J, Lindefors N, Riecher-Rössler A, Grobbee DE; EUFEST study group
Lancet 2008 Mar 29;371(9618):1085-97. doi: 10.1016/S0140-6736(08)60486-9. PMID: 18374841
Benazzi F
Curr Psychiatry Rep 2003 Jul;5(3):192-6. doi: 10.1007/s11920-003-0041-1. PMID: 12773271

Diagnosis

Teixeira da Cunha I, Silveira C, Freitas A, Gonçalves Pinho M
Acta Med Port 2024 Dec 2;37(12):823-830. Epub 2024 Sep 6 doi: 10.20344/amp.21714. PMID: 39239882
Hay A, Byers A, Sereno M, Basra MK, Dutta S
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD011458. doi: 10.1002/14651858.CD011458.pub2. PMID: 26599405Free PMC Article
Tandon R, Heckers S, Bustillo J, Barch DM, Gaebel W, Gur RE, Malaspina D, Owen MJ, Schultz S, Tsuang M, van Os J, Carpenter W
Schizophr Res 2013 Oct;150(1):26-30. Epub 2013 Jun 24 doi: 10.1016/j.schres.2013.04.034. PMID: 23806583
Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, Gheorghe MD, Rybakowski JK, Galderisi S, Libiger J, Hummer M, Dollfus S, López-Ibor JJ, Hranov LG, Gaebel W, Peuskens J, Lindefors N, Riecher-Rössler A, Grobbee DE; EUFEST study group
Lancet 2008 Mar 29;371(9618):1085-97. doi: 10.1016/S0140-6736(08)60486-9. PMID: 18374841
Adler CM, Strakowski SM
Psychiatr Clin North Am 2003 Mar;26(1):1-23. doi: 10.1016/s0193-953x(02)00085-0. PMID: 12683257

Therapy

Kahn RS, Kane JM, Correll CU, Arevalo C, Simmons A, Graham C, Yagoda S, Hu B, McDonnell D
J Clin Psychiatry 2023 Mar 22;84(3) doi: 10.4088/JCP.22m14674. PMID: 36946605
Wajima Z
J Nippon Med Sch 2019;86(2):70-80. doi: 10.1272/jnms.JNMS.2019_86-202. PMID: 31130568
Maia-de-Oliveira JP, Kandratavicius L, Nunes EA, Machado-de-Sousa JP, Hallak JE, Dursun SM
Curr Med Chem 2016;23(24):2680-2691. doi: 10.2174/0929867323666160721144549. PMID: 27450675
Hay A, Byers A, Sereno M, Basra MK, Dutta S
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD011458. doi: 10.1002/14651858.CD011458.pub2. PMID: 26599405Free PMC Article
Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, Gheorghe MD, Rybakowski JK, Galderisi S, Libiger J, Hummer M, Dollfus S, López-Ibor JJ, Hranov LG, Gaebel W, Peuskens J, Lindefors N, Riecher-Rössler A, Grobbee DE; EUFEST study group
Lancet 2008 Mar 29;371(9618):1085-97. doi: 10.1016/S0140-6736(08)60486-9. PMID: 18374841

Prognosis

Slot MIE, van Hell HH, Rossum IW, Dazzan P, Maat A, de Haan L, Crespo-Facorro B, Glenthøj B, Lawrie SM, McDonald C, Gruber O, van Amelsvoort T, Arango C, Kircher T, Nelson B, Galderisi S, Weiser M, Sachs G, Maatz A, Bressan RA, Kwon JS, Mizrahi R; PSYSCAN Consortium, McGuire P, Kahn RS
Schizophr Res 2024 Apr;266:237-248. Epub 2024 Mar 2 doi: 10.1016/j.schres.2024.02.018. PMID: 38431986
Sánchez-Torres AM, Amoretti S, Enguita-Germán M, Mezquida G, Moreno-Izco L, Panadero-Gómez R, Rementería L, Toll A, Rodriguez-Jimenez R, Roldán A, Pomarol-Clotet E, Ibáñez Á, Usall J, Contreras F, Vieta E, López-Ilundain JM, Merchán-Naranjo J, González-Pinto A, Berrocoso E, Bernardo M, Cuesta MJ; 2EPs group
Eur Neuropsychopharmacol 2023 Feb;67:53-65. Epub 2022 Dec 8 doi: 10.1016/j.euroneuro.2022.11.011. PMID: 36495858
Kanemoto K
Curr Top Behav Neurosci 2022;55:183-208. doi: 10.1007/7854_2021_234. PMID: 34426945
Farooq S, Johal RK, Ziff C, Naeem F
Cochrane Database Syst Rev 2017 Oct 24;10(10):CD011707. doi: 10.1002/14651858.CD011707.pub2. PMID: 29064090Free PMC Article
Benazzi F
Curr Psychiatry Rep 2003 Jul;5(3):192-6. doi: 10.1007/s11920-003-0041-1. PMID: 12773271

Clinical prediction guides

Teixeira da Cunha I, Silveira C, Freitas A, Gonçalves Pinho M
Acta Med Port 2024 Dec 2;37(12):823-830. Epub 2024 Sep 6 doi: 10.20344/amp.21714. PMID: 39239882
Hjell G, Rokicki J, Szabo A, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Djurovic S, Ueland T, Andreassen OA, Melle I, Lagerberg TV, Mørch-Johnsen L, Steen NE, Haukvik UK
BMC Psychiatry 2023 Sep 7;23(1):659. doi: 10.1186/s12888-023-05154-4. PMID: 37674162Free PMC Article
Robinson DG, Schooler NR, Marcy P, Gibbons RD, Hendricks Brown C, John M, Mueser KT, Penn DL, Rosenheck RA, Addington J, Brunette MF, Correll CU, Estroff SE, Mayer-Kalos PS, Gottlieb JD, Glynn SM, Lynde DW, Gingerich S, Pipes R, Miller AL, Severe JB, Kane JM
Schizophr Bull 2022 Sep 1;48(5):1021-1031. doi: 10.1093/schbul/sbac053. PMID: 35689478Free PMC Article
Widing L, Simonsen C, Flaaten CB, Haatveit B, Vik RK, Wold KF, Åsbø G, Ueland T, Melle I
Compr Psychiatry 2022 May;115:152310. Epub 2022 Mar 14 doi: 10.1016/j.comppsych.2022.152310. PMID: 35385814
Adler CM, Strakowski SM
Psychiatr Clin North Am 2003 Mar;26(1):1-23. doi: 10.1016/s0193-953x(02)00085-0. PMID: 12683257

Recent systematic reviews

Baeza I, Fortea A, Ilzarbe D, Sugranyes G
Paediatr Drugs 2023 Mar;25(2):135-149. Epub 2023 Jan 20 doi: 10.1007/s40272-023-00558-x. PMID: 36662369Free PMC Article
Ayano G, Tesfaw G, Shumet S
BMC Psychiatry 2019 Nov 27;19(1):370. doi: 10.1186/s12888-019-2361-7. PMID: 31775786Free PMC Article
Qu GB, Wu W, Wang LL, Tang X, Sun YH, Li J, Wang J
Acta Paediatr 2018 Aug;107(8):1327-1334. Epub 2018 Jan 18 doi: 10.1111/apa.14199. PMID: 29280182
Hay A, Byers A, Sereno M, Basra MK, Dutta S
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD011458. doi: 10.1002/14651858.CD011458.pub2. PMID: 26599405Free PMC Article
Matheson SL, Green MJ, Loo C, Carr VJ
Schizophr Res 2010 May;118(1-3):201-10. Epub 2010 Feb 1 doi: 10.1016/j.schres.2010.01.002. PMID: 20117918

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