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Adult periodontitis

MedGen UID:
120593
•Concept ID:
C0266929
•
Disease or Syndrome
Synonym: Periodontitis, chronic, adult
SNOMED CT: Chronic periodontitis (5689008); Chronic pericementitis (5689008); Chronic periodontal disease (5689008); Adult periodontitis (5689008)
 
Monarch Initiative: MONDO:0009850
OMIM®: 260950

Definition

Chronic periodontitis, formerly called adult periodontitis, is the most frequently occurring form of periodontitis and is characterized by slowly progressing alveolar bone destruction and attachment loss. Although chronic periodontitis is most prevalent in adults and has a slow progression, it can occur in children and adolescents and may have periods of rapid progression (Armitage, 1999). [from OMIM]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines

PubMed

Full-mouth treatment modalities (within 24 hours) for periodontitis in adults.
Jervøe-Storm PM, Eberhard J, Needleman I, Worthington HV, Jepsen S
Cochrane Database Syst Rev 2022 Jun 28;6(6):CD004622. doi: 10.1002/14651858.CD004622.pub4. PMID: 35763286Free PMC Article
Differential diagnosis in clinical trials of therapy for periodontitis.
Ranney RR
J Periodontol 1992 Dec;63(12 Suppl):1052-7. doi: 10.1902/jop.1992.63.12s.1052. PMID: 1479525
Diagnosis and treatment of localized juvenile periodontitis.
Zambon JJ, Christersson LA, Genco RJ
J Am Dent Assoc 1986 Aug;113(2):295-9. doi: 10.14219/jada.archive.1986.0152. PMID: 3528264

Recent clinical studies

Etiology

Parkinson's disease and oral health: A systematic review.
Verhoeff MC, Eikenboom D, Koutris M, de Vries R, Berendse HW, van Dijk KD, Lobbezoo F
Arch Oral Biol 2023 Jul;151:105712. Epub 2023 Apr 25 doi: 10.1016/j.archoralbio.2023.105712. PMID: 37120970
Success of non-surgical periodontal therapy in adult periodontitis patients: A retrospective analysis.
Van der Weijden GAF, Dekkers GJ, Slot DE
Int J Dent Hyg 2019 Nov;17(4):309-317. Epub 2019 May 16 doi: 10.1111/idh.12399. PMID: 30942938Free PMC Article
Risk factors for periodontal disease.
Genco RJ, Borgnakke WS
Periodontol 2000 2013 Jun;62(1):59-94. doi: 10.1111/j.1600-0757.2012.00457.x. PMID: 23574464
Nonsurgical periodontal therapy.
Drisko CH
Periodontol 2000 2001;25:77-88. doi: 10.1034/j.1600-0757.2001.22250106.x. PMID: 11155183
Not all patients are the same: systemic risk factors for adult periodontitis.
Wilson TG
Gen Dent 1999 Nov-Dec;47(6):580-8. PMID: 10687452

Diagnosis

Full-mouth treatment modalities (within 24 hours) for periodontitis in adults.
Jervøe-Storm PM, Eberhard J, Needleman I, Worthington HV, Jepsen S
Cochrane Database Syst Rev 2022 Jun 28;6(6):CD004622. doi: 10.1002/14651858.CD004622.pub4. PMID: 35763286Free PMC Article
Success of non-surgical periodontal therapy in adult periodontitis patients: A retrospective analysis.
Van der Weijden GAF, Dekkers GJ, Slot DE
Int J Dent Hyg 2019 Nov;17(4):309-317. Epub 2019 May 16 doi: 10.1111/idh.12399. PMID: 30942938Free PMC Article
Implant failure: etiology and complications.
Sakka S, Coulthard P
Med Oral Patol Oral Cir Bucal 2011 Jan 1;16(1):e42-4. doi: 10.4317/medoral.16.e42. PMID: 20526267
Periodontitis.
Flemmig TF
Ann Periodontol 1999 Dec;4(1):32-8. doi: 10.1902/annals.1999.4.1.32. PMID: 10863373
Diagnosis and treatment of localized juvenile periodontitis.
Zambon JJ, Christersson LA, Genco RJ
J Am Dent Assoc 1986 Aug;113(2):295-9. doi: 10.14219/jada.archive.1986.0152. PMID: 3528264

Therapy

Full-mouth treatment modalities (within 24 hours) for periodontitis in adults.
Jervøe-Storm PM, Eberhard J, Needleman I, Worthington HV, Jepsen S
Cochrane Database Syst Rev 2022 Jun 28;6(6):CD004622. doi: 10.1002/14651858.CD004622.pub4. PMID: 35763286Free PMC Article
Biorelevant and screening dissolution methods for minocycline hydrochloride microspheres intended for periodontal administration.
Patel SK, Greene AC, Desai SM, Rothstein S, Basha IT, MacPherson JS, Wang Y, Zou Y, Shehabeldin M, Sfeir CS, Little SR, Rohan LC
Int J Pharm 2021 Mar 1;596:120261. Epub 2021 Jan 21 doi: 10.1016/j.ijpharm.2021.120261. PMID: 33486044
Topical antiseptics and antibiotics in the initial therapy of chronic adult periodontitis: microbiological aspects.
Quirynen M, Teughels W, De Soete M, van Steenberghe D
Periodontol 2000 2002;28:72-90. doi: 10.1034/j.1600-0757.2002.280104.x. PMID: 12013349
Nonsurgical periodontal therapy.
Drisko CH
Periodontol 2000 2001;25:77-88. doi: 10.1034/j.1600-0757.2001.22250106.x. PMID: 11155183
Not all patients are the same: systemic risk factors for adult periodontitis.
Wilson TG
Gen Dent 1999 Nov-Dec;47(6):580-8. PMID: 10687452

Prognosis

Success of non-surgical periodontal therapy in adult periodontitis patients: A retrospective analysis.
Van der Weijden GAF, Dekkers GJ, Slot DE
Int J Dent Hyg 2019 Nov;17(4):309-317. Epub 2019 May 16 doi: 10.1111/idh.12399. PMID: 30942938Free PMC Article
Essential role for the gtfA gene encoding a putative glycosyltransferase in the adherence of Porphyromonas gingivalis.
Narimatsu M, Noiri Y, Itoh S, Noguchi N, Kawahara T, Ebisu S
Infect Immun 2004 May;72(5):2698-702. doi: 10.1128/IAI.72.5.2698-2702.2004. PMID: 15102778Free PMC Article
Not all patients are the same: systemic risk factors for adult periodontitis.
Wilson TG
Gen Dent 1999 Nov-Dec;47(6):580-8. PMID: 10687452
Periodontal diseases: epidemiology.
Papapanou PN
Ann Periodontol 1996 Nov;1(1):1-36. doi: 10.1902/annals.1996.1.1.1. PMID: 9118256
3 regimens of topical metronidazole compared with subgingival scaling on periodontal pathology in adults.
Klinge B, Attström R, Karring T, Kisch J, Lewin B, Stoltze K
J Clin Periodontol 1992 Oct;19(9 Pt 2):708-14. doi: 10.1111/j.1600-051x.1992.tb02533.x. PMID: 1447391

Clinical prediction guides

Biorelevant and screening dissolution methods for minocycline hydrochloride microspheres intended for periodontal administration.
Patel SK, Greene AC, Desai SM, Rothstein S, Basha IT, MacPherson JS, Wang Y, Zou Y, Shehabeldin M, Sfeir CS, Little SR, Rohan LC
Int J Pharm 2021 Mar 1;596:120261. Epub 2021 Jan 21 doi: 10.1016/j.ijpharm.2021.120261. PMID: 33486044
Essential role for the gtfA gene encoding a putative glycosyltransferase in the adherence of Porphyromonas gingivalis.
Narimatsu M, Noiri Y, Itoh S, Noguchi N, Kawahara T, Ebisu S
Infect Immun 2004 May;72(5):2698-702. doi: 10.1128/IAI.72.5.2698-2702.2004. PMID: 15102778Free PMC Article
Adhesion of Porphyromonas gingivalis to cultured pocket epithelium: mono- and multi-layered.
Papaioannou W, van Steenberghe D, Cassiman JJ, Dierickx K, Quirynen M
Clin Oral Investig 2003 Sep;7(3):162-6. Epub 2003 Aug 5 doi: 10.1007/s00784-003-0217-4. PMID: 12905052
The localization of periodontal-disease-associated bacteria in human periodontal pockets.
Noiri Y, Li L, Ebisu S
J Dent Res 2001 Oct;80(10):1930-4. doi: 10.1177/00220345010800101301. PMID: 11706954
Nonsurgical periodontal therapy.
Drisko CH
Periodontol 2000 2001;25:77-88. doi: 10.1034/j.1600-0757.2001.22250106.x. PMID: 11155183

Recent systematic reviews

Parkinson's disease and oral health: A systematic review.
Verhoeff MC, Eikenboom D, Koutris M, de Vries R, Berendse HW, van Dijk KD, Lobbezoo F
Arch Oral Biol 2023 Jul;151:105712. Epub 2023 Apr 25 doi: 10.1016/j.archoralbio.2023.105712. PMID: 37120970
Full-mouth treatment modalities (within 24 hours) for periodontitis in adults.
Jervøe-Storm PM, Eberhard J, Needleman I, Worthington HV, Jepsen S
Cochrane Database Syst Rev 2022 Jun 28;6(6):CD004622. doi: 10.1002/14651858.CD004622.pub4. PMID: 35763286Free PMC Article
Effect of anxiety and psychologic stress on periodontal health: a systematic review and meta-analysis.
Aggarwal K, Gupta J, Kaur RK, Bansal D, Jain A
Quintessence Int 2022 Jan 7;53(2):144-154. doi: 10.3290/j.qi.b2091191. PMID: 34595909
Behavioural interventions that have the potential to improve self-care in adults with periodontitis: a systematic review.
Järvinen M, Stolt M, Honkala E, Leino-Kilpi H, Pöllänen M
Acta Odontol Scand 2018 Nov;76(8):612-620. Epub 2018 Jul 25 doi: 10.1080/00016357.2018.1490964. PMID: 30045652

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