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Adipsic Diabetes Insipidus

MedGen UID:
1373297
Concept ID:
C4329279
Disease or Syndrome

Definition

Diabetes insipidus complicated by a deficient or absent thirst response to hyperosmolality, usually as a result of hypothalamic damage or dysfunction. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdipsic Diabetes Insipidus

Professional guidelines

PubMed

Tomkins M, Lawless S, Martin-Grace J, Sherlock M, Thompson CJ
J Clin Endocrinol Metab 2022 Sep 28;107(10):2701-2715. doi: 10.1210/clinem/dgac381. PMID: 35771962Free PMC Article

Recent clinical studies

Etiology

Yang T, Wu W, Liu X, Xiang B, Sun Q, Zhang S, Zhuang Y, Yin Z, Zhang Q, Cao Y, Ye H
Endocr Pract 2024 Feb;30(2):141-145. Epub 2023 Nov 27 doi: 10.1016/j.eprac.2023.11.012. PMID: 38029928
Eisenberg Y, Frohman LA
Endocr Pract 2016 Jan;22(1):76-83. Epub 2015 Sep 24 doi: 10.4158/EP15940.RA. PMID: 26401579
Miljic D, Miljic P, Doknic M, Pekic S, Stojanovic M, Petakov M, Popovic V
Hormones (Athens) 2014 Jul-Sep;13(3):420-3. doi: 10.14310/horm.2002.1496. PMID: 25079469
Janus DM, Wojcik M, Zygmunt-Górska A, Wyrobek L, Urbanik A, Starzyk JB
Indian J Pediatr 2014 Dec;81(12):1307-14. Epub 2014 May 2 doi: 10.1007/s12098-014-1421-8. PMID: 24788913
Sinha A, Ball S, Jenkins A, Hale J, Cheetham T
Pituitary 2011 Dec;14(4):307-11. doi: 10.1007/s11102-011-0294-3. PMID: 21301966

Diagnosis

Tomkins M, Lawless S, Martin-Grace J, Sherlock M, Thompson CJ
J Clin Endocrinol Metab 2022 Sep 28;107(10):2701-2715. doi: 10.1210/clinem/dgac381. PMID: 35771962Free PMC Article
AlShoomi AM, Alkanhal KI, Alsaheel AY
Am J Case Rep 2021 Dec 13;22:e934193. doi: 10.12659/AJCR.934193. PMID: 34898594Free PMC Article
Kothari V, Cardona Z, Eisenberg Y
Handb Clin Neurol 2021;181:261-273. doi: 10.1016/B978-0-12-820683-6.00019-1. PMID: 34238462
Zhang Y, Wang D, Feng Y, Zhang W, Zeng X
J Int Med Res 2018 Nov;46(11):4829-4836. Epub 2018 Oct 1 doi: 10.1177/0300060518800114. PMID: 30270804Free PMC Article
Eisenberg Y, Frohman LA
Endocr Pract 2016 Jan;22(1):76-83. Epub 2015 Sep 24 doi: 10.4158/EP15940.RA. PMID: 26401579

Therapy

Chua M, Tay DYK, Ng YS, Rajasoorya C
Ann Acad Med Singap 2021 Feb;50(2):181-183. doi: 10.47102/annals-acadmedsg.2020418. PMID: 33733264
Pérez MA, Millán HA, Naranjo JA, Flórez Romero A
BMJ Case Rep 2019 Jan 31;12(1) doi: 10.1136/bcr-2018-225903. PMID: 30709829Free PMC Article
Tan J, Ndoro S, Okafo U, Garrahy A, Agha A, Rawluk D
N Z Med J 2016 Dec 16;129(1447):86-90. PMID: 27977657
Miljic D, Miljic P, Doknic M, Pekic S, Stojanovic M, Petakov M, Popovic V
Hormones (Athens) 2014 Jul-Sep;13(3):420-3. doi: 10.14310/horm.2002.1496. PMID: 25079469
Sherlock M, Agha A, Crowley R, Smith D, Thompson CJ
Pituitary 2006;9(1):59-64. doi: 10.1007/s11102-006-8280-x. PMID: 16703410

Prognosis

Tudor RM, Thompson CJ
Pituitary 2019 Jun;22(3):296-304. doi: 10.1007/s11102-018-0917-z. PMID: 30334138
Kreutz J, Potorac I, Lutteri L, Gennigens C, Martin D, Daly AF, Bonneville JF, Tshibanda L, Beckers A
Ann Endocrinol (Paris) 2017 Jul;78(3):141-145. Epub 2017 May 5 doi: 10.1016/j.ando.2016.10.005. PMID: 28483362
Cuesta M, Hannon MJ, Thompson CJ
Pituitary 2017 Jun;20(3):372-380. doi: 10.1007/s11102-016-0784-4. PMID: 28074401
O'Reilly MW, Sexton DJ, Dennedy MC, Counihan TJ, Finucane FM, O'Brien T, O'Regan AW
QJM 2015 Aug;108(8):657-9. Epub 2013 Feb 14 doi: 10.1093/qjmed/hct023. PMID: 23417911

Clinical prediction guides

Seki Y, Sugawara S, Suzuki S, Minakuchi Y, Kusuki K, Mizuno Y
Endocr J 2024 Nov 1;71(11):1087-1092. Epub 2024 Aug 7 doi: 10.1507/endocrj.EJ23-0643. PMID: 39111874
Tudor RM, Thompson CJ
Pituitary 2019 Jun;22(3):296-304. doi: 10.1007/s11102-018-0917-z. PMID: 30334138
Cuesta M, Hannon MJ, Thompson CJ
Pituitary 2017 Jun;20(3):372-380. doi: 10.1007/s11102-016-0784-4. PMID: 28074401
Janus DM, Wojcik M, Zygmunt-Górska A, Wyrobek L, Urbanik A, Starzyk JB
Indian J Pediatr 2014 Dec;81(12):1307-14. Epub 2014 May 2 doi: 10.1007/s12098-014-1421-8. PMID: 24788913
Sinha A, Ball S, Jenkins A, Hale J, Cheetham T
Pituitary 2011 Dec;14(4):307-11. doi: 10.1007/s11102-011-0294-3. PMID: 21301966

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