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Michaelis-Gutmann bodies

MedGen UID:
137695
Concept ID:
C0333746
Finding
Synonyms: Malakoplakia; MG body; Michaelis-Gutmann body; Michaelis-Gutmann Body
SNOMED CT: Michaelis-Gutmann body (82662004); MG body (82662004)
 
HPO: HP:0033046

Definition

Basophilic intracytoplasmic inclusions in macrophages. The inclusions have a small, round laminated appearance. Electron microscopy of Michaelis-Gutmann bodies exhibits partially digested bacteria. [from HPO]

Term Hierarchy

Recent clinical studies

Etiology

Xia Z, Du D, Zhang Z, Hu Z, Liu Z
Int Urol Nephrol 2024 Jun;56(6):1779-1784. Epub 2024 Jan 18 doi: 10.1007/s11255-023-03920-7. PMID: 38236373
Șerban C, Toma A, Voicu DC, Popazu C, Firescu D, Țocu G, Mihailov R, Rebegea L
Medicina (Kaunas) 2023 Jan 12;59(1) doi: 10.3390/medicina59010156. PMID: 36676780Free PMC Article
Koutserimpas C, Ioannidis A, Demonakou M, Siaperas P, Skarpas A, Velimezis G, Karanikas I
G Chir 2018 Mar-Apr;39(2):97-100. PMID: 29694309
de Peralta-Venturina MN, Clubb FJ, Kielhofner MA
Am J Clin Pathol 1994 Oct;102(4):459-63. doi: 10.1093/ajcp/102.4.459. PMID: 7942603
Dobyan DC, Truong LD, Eknoyan G
Am J Kidney Dis 1993 Aug;22(2):243-52. doi: 10.1016/s0272-6386(12)70313-x. PMID: 8352248

Diagnosis

Dominguez D, Eichhorn J, Palot Manzil FF
Clin Nucl Med 2025 Jan 1;50(1):75-76. Epub 2024 Oct 30 doi: 10.1097/RLU.0000000000005536. PMID: 39480213
Prakash A, Noor N, Marchant A, Ghori M, Molani RA
J Ayub Med Coll Abbottabad 2024 Apr-Jun;36(2):451-453. doi: 10.55519/JAMC-02-12643. PMID: 39610001
Zhao X, Long Z, Yu L, Wang X, Fu Z
Clin Nucl Med 2023 Oct 1;48(10):e496-e499. Epub 2023 Sep 2 doi: 10.1097/RLU.0000000000004799. PMID: 37682619
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Dobyan DC, Truong LD, Eknoyan G
Am J Kidney Dis 1993 Aug;22(2):243-52. doi: 10.1016/s0272-6386(12)70313-x. PMID: 8352248

Therapy

Fatola A, Johnson BC, Walsh L, Fang D, White MJ, Le D, Atta MG, Sperati CJ, Hager DN
BMC Nephrol 2024 Jun 18;25(1):200. doi: 10.1186/s12882-024-03640-9. PMID: 38890600Free PMC Article
Cięszczyk K, Puderecki M, Wronecki L, Burdan F, Szumiło J
Folia Med Cracov 2019;59(2):67-74. PMID: 31659350
Lane RJ, Kradin R, Xia D, Buchan CA, Turbett S, Kotton CN, Mansour MK
Transplant Proc 2019 Apr;51(3):871-874. Epub 2019 Jan 8 doi: 10.1016/j.transproceed.2018.11.008. PMID: 30979478Free PMC Article
Kwon HJ, Yoo KH, Kim IY, Lee S, Jang HR, Kwon GY
J Korean Med Sci 2015 Jan;30(1):110-4. Epub 2014 Dec 23 doi: 10.3346/jkms.2015.30.1.110. PMID: 25552891Free PMC Article
Kohl SK, Hans CP
Arch Pathol Lab Med 2008 Jan;132(1):113-7. doi: 10.5858/2008-132-113-CM. PMID: 18181662

Prognosis

Cięszczyk K, Puderecki M, Wronecki L, Burdan F, Szumiło J
Folia Med Cracov 2019;59(2):67-74. PMID: 31659350
Coates M, Del Pero MM, Nassif R
Head Neck Pathol 2016 Dec;10(4):444-450. Epub 2016 May 6 doi: 10.1007/s12105-016-0721-x. PMID: 27154024Free PMC Article
Mulè A, Petrone G, Santoro A, Sanguinetti M, Meacci E, Coli A, Margaritora S
Int J Immunopathol Pharmacol 2012 Jul-Sep;25(3):703-12. doi: 10.1177/039463201202500316. PMID: 23058020
Kohl SK, Hans CP
Arch Pathol Lab Med 2008 Jan;132(1):113-7. doi: 10.5858/2008-132-113-CM. PMID: 18181662
Dobyan DC, Truong LD, Eknoyan G
Am J Kidney Dis 1993 Aug;22(2):243-52. doi: 10.1016/s0272-6386(12)70313-x. PMID: 8352248

Clinical prediction guides

Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Mulè A, Petrone G, Santoro A, Sanguinetti M, Meacci E, Coli A, Margaritora S
Int J Immunopathol Pharmacol 2012 Jul-Sep;25(3):703-12. doi: 10.1177/039463201202500316. PMID: 23058020
Deguchi T, Kuriyama M, Shinoda I, Maeda S, Takeuchi T, Sakai S, Ban Y, Nishiura T
Urology 1985 Jul;26(1):92-4. doi: 10.1016/0090-4295(85)90270-5. PMID: 3892853
Paquin F, Schick E, Parent C
Urology 1983 Feb;21(2):194-8. doi: 10.1016/0090-4295(83)90026-2. PMID: 6297143
An T, Ferenczy A, Wilens SL, Melicow MM
Hum Pathol 1974 Nov;5(6):753-8. doi: 10.1016/s0046-8177(74)80044-4. PMID: 4424069

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