U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal endocrine morphology

MedGen UID:
1376980
•Concept ID:
C4476950
•
Anatomical Abnormality
HPO: HP:0031071

Definition

Any anomaly of the structure of an organ ofthe endocrine system. [from HPO]

Professional guidelines

PubMed

Anti-Müllerian Hormone in Pathogenesis, Diagnostic and Treatment of PCOS.
Rudnicka E, Kunicki M, Calik-Ksepka A, Suchta K, Duszewska A, Smolarczyk K, Smolarczyk R
Int J Mol Sci 2021 Nov 19;22(22) doi: 10.3390/ijms222212507. PMID: 34830389Free PMC Article
Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine.
Khan J, Asoom LIA, Sunni AA, Rafique N, Latif R, Saif SA, Almandil NB, Almohazey D, AbdulAzeez S, Borgio JF
Biomed Pharmacother 2021 Jul;139:111557. Epub 2021 May 17 doi: 10.1016/j.biopha.2021.111557. PMID: 34243621
Pathogenesis and treatment of primary aldosteronism.
Zennaro MC, Boulkroun S, Fernandes-Rosa FL
Nat Rev Endocrinol 2020 Oct;16(10):578-589. Epub 2020 Jul 28 doi: 10.1038/s41574-020-0382-4. PMID: 32724183

Recent clinical studies

Etiology

Disorders of sex development: insights from targeted gene sequencing of a large international patient cohort.
Eggers S, Sadedin S, van den Bergen JA, Robevska G, Ohnesorg T, Hewitt J, Lambeth L, Bouty A, Knarston IM, Tan TY, Cameron F, Werther G, Hutson J, O'Connell M, Grover SR, Heloury Y, Zacharin M, Bergman P, Kimber C, Brown J, Webb N, Hunter MF, Srinivasan S, Titmuss A, Verge CF, Mowat D, Smith G, Smith J, Ewans L, Shalhoub C, Crock P, Cowell C, Leong GM, Ono M, Lafferty AR, Huynh T, Visser U, Choong CS, McKenzie F, Pachter N, Thompson EM, Couper J, Baxendale A, Gecz J, Wheeler BJ, Jefferies C, MacKenzie K, Hofman P, Carter P, King RI, Krausz C, van Ravenswaaij-Arts CM, Looijenga L, Drop S, Riedl S, Cools M, Dawson A, Juniarto AZ, Khadilkar V, Khadilkar A, Bhatia V, Dũng VC, Atta I, Raza J, Thi Diem Chi N, Hao TK, Harley V, Koopman P, Warne G, Faradz S, Oshlack A, Ayers KL, Sinclair AH
Genome Biol 2016 Nov 29;17(1):243. doi: 10.1186/s13059-016-1105-y. PMID: 27899157Free PMC Article
Epidemic of fear.
Normile D
Science 2016 Mar 4;351(6277):1022-3. doi: 10.1126/science.351.6277.1022. PMID: 26941301
Rathke's cleft cyst.
Larkin S, Karavitaki N, Ansorge O
Handb Clin Neurol 2014;124:255-69. doi: 10.1016/B978-0-444-59602-4.00017-4. PMID: 25248592
Disorders of adrenal development.
Ferraz-de-Souza B, Achermann JC
Endocr Dev 2008;13:19-32. doi: 10.1159/000134753. PMID: 18493131
Splenogonadal fusion.
Balaji KC, Caldamone AA, Rabinowitz R, Ortenberg J, Diamond DA
J Urol 1996 Aug;156(2 Pt 2):854-6. doi: 10.1097/00005392-199608001-00086. PMID: 8683800

Diagnosis

Update on canine anorchia: A review.
Cicirelli V, Burgio M, Mrenoshki D, Cseh S, Aiudi G, Lacalandra GM
Vet Med Sci 2023 Mar;9(2):600-603. Epub 2023 Jan 3 doi: 10.1002/vms3.1033. PMID: 36597410Free PMC Article
Imaging of Adrenal-Related Endocrine Disorders.
Yalniz C, Morani AC, Waguespack SG, Elsayes KM
Radiol Clin North Am 2020 Nov;58(6):1099-1113. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.010. PMID: 33040851
Rathke's cleft cyst.
Larkin S, Karavitaki N, Ansorge O
Handb Clin Neurol 2014;124:255-69. doi: 10.1016/B978-0-444-59602-4.00017-4. PMID: 25248592
Parathyroid imaging.
Johnson NA, Carty SE, Tublin ME
Radiol Clin North Am 2011 May;49(3):489-509, vi. doi: 10.1016/j.rcl.2011.02.009. PMID: 21569907
Bifid epiglottis.
Goldenberg JD, Holinger LD, Bressler FJ, Hutchinson LR
Ann Otol Rhinol Laryngol 1996 Feb;105(2):155-7. doi: 10.1177/000348949610500211. PMID: 8659937

Therapy

Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.
Merke DP, Auchus RJ
N Engl J Med 2020 Sep 24;383(13):1248-1261. doi: 10.1056/NEJMra1909786. PMID: 32966723
Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity.
Zeng X, Xie YJ, Liu YT, Long SL, Mo ZC
Clin Chim Acta 2020 Mar;502:214-221. Epub 2019 Nov 13 doi: 10.1016/j.cca.2019.11.003. PMID: 31733195
Epidemic of fear.
Normile D
Science 2016 Mar 4;351(6277):1022-3. doi: 10.1126/science.351.6277.1022. PMID: 26941301
Uterine factors.
Jaslow CR
Obstet Gynecol Clin North Am 2014 Mar;41(1):57-86. doi: 10.1016/j.ogc.2013.10.002. PMID: 24491984
The embryology of testicular descent.
Wensing CJ
Horm Res 1988;30(4-5):144-52. doi: 10.1159/000181051. PMID: 2907890

Prognosis

AMH and other markers of ovarian function in patients with Turner syndrome - a single center experience of transition from pediatric to gynecological follow up.
Hagen CP, Fischer MB, Mola G, Mikkelsen TB, Cleemann LH, Gravholt CH, Viuff MH, Juul A, Pedersen AT, Main KM
Front Endocrinol (Lausanne) 2023;14:1173600. Epub 2023 Jun 29 doi: 10.3389/fendo.2023.1173600. PMID: 37455919Free PMC Article
Imaging of Adrenal-Related Endocrine Disorders.
Yalniz C, Morani AC, Waguespack SG, Elsayes KM
Radiol Clin North Am 2020 Nov;58(6):1099-1113. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.010. PMID: 33040851
Disorders of thyroid morphogenesis.
Abu-Khudir R, Larrivée-Vanier S, Wasserman JD, Deladoëy J
Best Pract Res Clin Endocrinol Metab 2017 Mar;31(2):143-159. Epub 2017 Apr 21 doi: 10.1016/j.beem.2017.04.008. PMID: 28648504
The hypothalamus.
Settle M
Neonatal Netw 2000 Sep;19(6):9-14. doi: 10.1891/0730-0832.19.6.9. PMID: 11949123
Cryptorchidism.
Rabinowitz R, Hulbert WC Jr
Pediatr Rev 1994 Jul;15(7):272-4. doi: 10.1542/pir.15-7-272. PMID: 7916154

Clinical prediction guides

P450 Oxidoreductase Deficiency: A Systematic Review and Meta-analysis of Genotypes, Phenotypes, and Their Relationships.
Dean B, Chrisp GL, Quartararo M, Maguire AM, Hameed S, King BR, Munns CF, Torpy DJ, Falhammar H, Rushworth RL
J Clin Endocrinol Metab 2020 Mar 1;105(3) doi: 10.1210/clinem/dgz255. PMID: 31825489
Perspectives in Pediatric Pathology, Chapter 6. Male Undermasculinization.
Nistal M, Paniagua R, González-Peramato P, Reyes-Múgica M
Pediatr Dev Pathol 2015 Jul-Aug;18(4):279-96. Epub 2014 Aug 8 doi: 10.2350/14-04-1465-PB.1. PMID: 25105706
Perspectives in Pediatric Pathology, Chapter 5. Gonadal Dysgenesis.
Nistal M, Paniagua R, González-Peramato P, Reyes-Múgica M
Pediatr Dev Pathol 2015 Jul-Aug;18(4):259-78. Epub 2014 Aug 8 doi: 10.2350/14-04-1471-PB.1. PMID: 25105336
Cryptorchidism.
Hutson JM, Balic A, Nation T, Southwell B
Semin Pediatr Surg 2010 Aug;19(3):215-24. doi: 10.1053/j.sempedsurg.2010.04.001. PMID: 20610195
Pathogenesis of cryptorchidism.
Hadziselimovic F, Girard J
Horm Res 1977;8(2):76-83. doi: 10.1159/000178783. PMID: 20399

Recent systematic reviews

Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies.
Sanchez-Garrido MA, Tena-Sempere M
Mol Metab 2020 May;35:100937. Epub 2020 Feb 5 doi: 10.1016/j.molmet.2020.01.001. PMID: 32244180Free PMC Article
Cannabis and Male Fertility: A Systematic Review.
Payne KS, Mazur DJ, Hotaling JM, Pastuszak AW
J Urol 2019 Oct;202(4):674-681. Epub 2019 Sep 6 doi: 10.1097/JU.0000000000000248. PMID: 30916627Free PMC Article
Ovarian torsion in pediatric and adolescent patients: A systematic review.
Dasgupta R, Renaud E, Goldin AB, Baird R, Cameron DB, Arnold MA, Diefenbach KA, Gosain A, Grabowski J, Guner YS, Jancelewicz T, Kawaguchi A, Lal DR, Oyetunji TA, Ricca RL, Shelton J, Somme S, Williams RF, Downard CD
J Pediatr Surg 2018 Jul;53(7):1387-1391. Epub 2017 Nov 16 doi: 10.1016/j.jpedsurg.2017.10.053. PMID: 29153467
Impact of fetal alcohol exposure on body systems: A systematic review.
Caputo C, Wood E, Jabbour L
Birth Defects Res C Embryo Today 2016 Jun;108(2):174-80. Epub 2016 Jun 13 doi: 10.1002/bdrc.21129. PMID: 27297122
Effects of aging on the male reproductive system.
Gunes S, Hekim GN, Arslan MA, Asci R
J Assist Reprod Genet 2016 Apr;33(4):441-54. Epub 2016 Feb 11 doi: 10.1007/s10815-016-0663-y. PMID: 26867640Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...