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Unresectable Osteosarcoma

MedGen UID:
1379232
Concept ID:
C4331477
Neoplastic Process

Definition

An osteosarcoma which is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Osteosarcoma

Professional guidelines

PubMed

Mahajan A, Woo SY, Kornguth DG, Hughes D, Huh W, Chang EL, Herzog CE, Pelloski CE, Anderson P
Pediatr Blood Cancer 2008 May;50(5):976-82. doi: 10.1002/pbc.21451. PMID: 18213710

Recent clinical studies

Etiology

Martin-Broto J, Redondo A, Valverde C, Vaz MA, Mora J, Garcia Del Muro X, Gutierrez A, Tous C, Carnero A, Marcilla D, Carranza A, Sancho P, Martinez-Trufero J, Diaz-Beveridge R, Cruz J, Encinas V, Taron M, Moura DS, Luna P, Hindi N, Lopez-Pousa A
Ann Oncol 2017 Dec 1;28(12):2994-2999. doi: 10.1093/annonc/mdx536. PMID: 29045512
Grignani G, Palmerini E, Ferraresi V, D'Ambrosio L, Bertulli R, Asaftei SD, Tamburini A, Pignochino Y, Sangiolo D, Marchesi E, Capozzi F, Biagini R, Gambarotti M, Fagioli F, Casali PG, Picci P, Ferrari S, Aglietta M; Italian Sarcoma Group
Lancet Oncol 2015 Jan;16(1):98-107. Epub 2014 Dec 11 doi: 10.1016/S1470-2045(14)71136-2. PMID: 25498219
Matsunobu A, Imai R, Kamada T, Imaizumi T, Tsuji H, Tsujii H, Shioyama Y, Honda H, Tatezaki S; Working Group for Bone and Soft Tissue Sarcomas
Cancer 2012 Sep 15;118(18):4555-63. Epub 2012 Feb 22 doi: 10.1002/cncr.27451. PMID: 22359113
Grignani G, Palmerini E, Dileo P, Asaftei SD, D'Ambrosio L, Pignochino Y, Mercuri M, Picci P, Fagioli F, Casali PG, Ferrari S, Aglietta M
Ann Oncol 2012 Feb;23(2):508-16. Epub 2011 Apr 28 doi: 10.1093/annonc/mdr151. PMID: 21527590
Ferguson WS, Harris MB, Goorin AM, Gebhardt MC, Link MP, Shochat SJ, Siegal GP, Devidas M, Grier HE
J Pediatr Hematol Oncol 2001 Aug-Sep;23(6):340-8. doi: 10.1097/00043426-200108000-00004. PMID: 11563767

Diagnosis

Xie L, Xu J, Sun X, Tang X, Yan T, Yang R, Guo W
Oncologist 2019 Jul;24(7):e542-e550. Epub 2018 Dec 17 doi: 10.1634/theoncologist.2018-0542. PMID: 30559126Free PMC Article
Cathomas R, Rothermundt C, Bode B, Fuchs B, von Moos R, Schwitter M
Oncology 2015;88(4):257-60. Epub 2014 Dec 17 doi: 10.1159/000369975. PMID: 25531914
Mavrogenis AF, Rossi G, Rimondi E, Calabrò T, Papagelopoulos PJ, Ruggieri P
Eur J Orthop Surg Traumatol 2014 Dec;24(8):1351-6. Epub 2013 Sep 6 doi: 10.1007/s00590-013-1312-0. PMID: 24062055
Errani C, Longhi A, Rossi G, Rimondi E, Biazzo A, Toscano A, Alì N, Ruggieri P, Alberghini M, Picci P, Bacci G, Mercuri M
Expert Rev Anticancer Ther 2011 Feb;11(2):217-27. doi: 10.1586/era.10.172. PMID: 21342041
Ferguson WS, Harris MB, Goorin AM, Gebhardt MC, Link MP, Shochat SJ, Siegal GP, Devidas M, Grier HE
J Pediatr Hematol Oncol 2001 Aug-Sep;23(6):340-8. doi: 10.1097/00043426-200108000-00004. PMID: 11563767

Therapy

Zhang S, Wu Y, Yu J, Ma C, Wang Y, Wang Y, Li L, Zhang LW
ACS Biomater Sci Eng 2022 Dec 12;8(12):5329-5337. Epub 2022 Nov 16 doi: 10.1021/acsbiomaterials.2c00880. PMID: 36383732
Grignani G, Palmerini E, Ferraresi V, D'Ambrosio L, Bertulli R, Asaftei SD, Tamburini A, Pignochino Y, Sangiolo D, Marchesi E, Capozzi F, Biagini R, Gambarotti M, Fagioli F, Casali PG, Picci P, Ferrari S, Aglietta M; Italian Sarcoma Group
Lancet Oncol 2015 Jan;16(1):98-107. Epub 2014 Dec 11 doi: 10.1016/S1470-2045(14)71136-2. PMID: 25498219
Mavrogenis AF, Rossi G, Rimondi E, Calabrò T, Papagelopoulos PJ, Ruggieri P
Eur J Orthop Surg Traumatol 2014 Dec;24(8):1351-6. Epub 2013 Sep 6 doi: 10.1007/s00590-013-1312-0. PMID: 24062055
Grignani G, Palmerini E, Dileo P, Asaftei SD, D'Ambrosio L, Pignochino Y, Mercuri M, Picci P, Fagioli F, Casali PG, Ferrari S, Aglietta M
Ann Oncol 2012 Feb;23(2):508-16. Epub 2011 Apr 28 doi: 10.1093/annonc/mdr151. PMID: 21527590
Errani C, Longhi A, Rossi G, Rimondi E, Biazzo A, Toscano A, Alì N, Ruggieri P, Alberghini M, Picci P, Bacci G, Mercuri M
Expert Rev Anticancer Ther 2011 Feb;11(2):217-27. doi: 10.1586/era.10.172. PMID: 21342041

Prognosis

Xie L, Xu J, Sun X, Tang X, Yan T, Yang R, Guo W
Oncologist 2019 Jul;24(7):e542-e550. Epub 2018 Dec 17 doi: 10.1634/theoncologist.2018-0542. PMID: 30559126Free PMC Article
Mavrogenis AF, Rossi G, Rimondi E, Calabrò T, Papagelopoulos PJ, Ruggieri P
Eur J Orthop Surg Traumatol 2014 Dec;24(8):1351-6. Epub 2013 Sep 6 doi: 10.1007/s00590-013-1312-0. PMID: 24062055
Grignani G, Palmerini E, Dileo P, Asaftei SD, D'Ambrosio L, Pignochino Y, Mercuri M, Picci P, Fagioli F, Casali PG, Ferrari S, Aglietta M
Ann Oncol 2012 Feb;23(2):508-16. Epub 2011 Apr 28 doi: 10.1093/annonc/mdr151. PMID: 21527590
Mahajan A, Woo SY, Kornguth DG, Hughes D, Huh W, Chang EL, Herzog CE, Pelloski CE, Anderson P
Pediatr Blood Cancer 2008 May;50(5):976-82. doi: 10.1002/pbc.21451. PMID: 18213710
Ferguson WS, Harris MB, Goorin AM, Gebhardt MC, Link MP, Shochat SJ, Siegal GP, Devidas M, Grier HE
J Pediatr Hematol Oncol 2001 Aug-Sep;23(6):340-8. doi: 10.1097/00043426-200108000-00004. PMID: 11563767

Clinical prediction guides

Mavrogenis AF, Rossi G, Rimondi E, Calabrò T, Papagelopoulos PJ, Ruggieri P
Eur J Orthop Surg Traumatol 2014 Dec;24(8):1351-6. Epub 2013 Sep 6 doi: 10.1007/s00590-013-1312-0. PMID: 24062055
Matsunobu A, Imai R, Kamada T, Imaizumi T, Tsuji H, Tsujii H, Shioyama Y, Honda H, Tatezaki S; Working Group for Bone and Soft Tissue Sarcomas
Cancer 2012 Sep 15;118(18):4555-63. Epub 2012 Feb 22 doi: 10.1002/cncr.27451. PMID: 22359113
Grignani G, Palmerini E, Dileo P, Asaftei SD, D'Ambrosio L, Pignochino Y, Mercuri M, Picci P, Fagioli F, Casali PG, Ferrari S, Aglietta M
Ann Oncol 2012 Feb;23(2):508-16. Epub 2011 Apr 28 doi: 10.1093/annonc/mdr151. PMID: 21527590
Franzius C, Bielack S, Flege S, Eckardt J, Sciuk J, Jürgens H, Schober O
Nuklearmedizin 2001 Dec;40(6):215-20. PMID: 11797510

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