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Increased Arden ratio of electrooculogram

MedGen UID:
1379641
•Concept ID:
C4477008
•
Finding
Synonym: Increased Arden ratio of EOG
 
HPO: HP:0031155

Definition

An abnormal increase in the Arden ratio, which is the ratio between the light peak and the dark trough of the smoothed (physiologic) EOG record. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased Arden ratio of electrooculogram

Recent clinical studies

Etiology

Non-syndromic OTX2-associated pattern dystrophy: a 10-year multimodal imaging study.
Ramakrishnan P, Kenworthy MK, Alexis JA, Thompson JA, Lamey TM, Chen FK
Doc Ophthalmol 2024 Oct;149(2):115-123. Epub 2024 Jul 18 doi: 10.1007/s10633-024-09983-w. PMID: 39023660Free PMC Article
The effect of pseudophakia on retinal and cortical functions.
Akay F, Mutlu FM, Gundogan FC
Med Glas (Zenica) 2014 Feb;11(1):120-6. PMID: 24496352
Systematic screening of BEST1 and PRPH2 in juvenile and adult vitelliform macular dystrophies: a rationale for molecular analysis.
Meunier I, Sénéchal A, Dhaenens CM, Arndt C, Puech B, Defoort-Dhellemmes S, Manes G, Chazalette D, Mazoir E, Bocquet B, Hamel CP
Ophthalmology 2011 Jun;118(6):1130-6. Epub 2011 Jan 26 doi: 10.1016/j.ophtha.2010.10.010. PMID: 21269699
The effects of vigabatrin on electrophysiology and visual fields in epileptics: a controlled study with a discussion of possible mechanisms.
Comaish IF, Gorman C, Brimlow GM, Barber C, Orr GM, Galloway NR
Doc Ophthalmol 2002 Mar;104(2):195-212. doi: 10.1023/a:1014603229383. PMID: 11999627
Clinical implications of reported timolol-induced side effects.
Levine L
Am J Optom Physiol Opt 1982 Jun;59(6):523-8. doi: 10.1097/00006324-198206000-00014. PMID: 6125102

Diagnosis

Non-syndromic OTX2-associated pattern dystrophy: a 10-year multimodal imaging study.
Ramakrishnan P, Kenworthy MK, Alexis JA, Thompson JA, Lamey TM, Chen FK
Doc Ophthalmol 2024 Oct;149(2):115-123. Epub 2024 Jul 18 doi: 10.1007/s10633-024-09983-w. PMID: 39023660Free PMC Article
Systematic screening of BEST1 and PRPH2 in juvenile and adult vitelliform macular dystrophies: a rationale for molecular analysis.
Meunier I, Sénéchal A, Dhaenens CM, Arndt C, Puech B, Defoort-Dhellemmes S, Manes G, Chazalette D, Mazoir E, Bocquet B, Hamel CP
Ophthalmology 2011 Jun;118(6):1130-6. Epub 2011 Jan 26 doi: 10.1016/j.ophtha.2010.10.010. PMID: 21269699
Rod-cone dystrophy with maculopathy in genetic glutathione synthetase deficiency: a morphologic and electrophysiologic study.
Burstedt MS, Ristoff E, Larsson A, Wachtmeister L
Ophthalmology 2009 Feb;116(2):324-31. Epub 2008 Dec 27 doi: 10.1016/j.ophtha.2008.09.007. PMID: 19111905
Computer-assisted analysis of the electro-oculogram.
Gosbell AD, Barry WR, Favilla I, Burkitt G
Aust N Z J Ophthalmol 1991 Nov;19(4):335-41. doi: 10.1111/j.1442-9071.1991.tb00682.x. PMID: 1789974
Clinical implications of reported timolol-induced side effects.
Levine L
Am J Optom Physiol Opt 1982 Jun;59(6):523-8. doi: 10.1097/00006324-198206000-00014. PMID: 6125102

Therapy

Effect of docosahexaenoic acid supplementation on the macular function of patients with Best vitelliform macular dystrophy: randomized clinical trial.
Lee TK, Clandinin MT, Hébert M, MacDonald IM
Can J Ophthalmol 2010 Oct;45(5):514-9. doi: 10.3129/i10-028. PMID: 20847757
The effects of vigabatrin on electrophysiology and visual fields in epileptics: a controlled study with a discussion of possible mechanisms.
Comaish IF, Gorman C, Brimlow GM, Barber C, Orr GM, Galloway NR
Doc Ophthalmol 2002 Mar;104(2):195-212. doi: 10.1023/a:1014603229383. PMID: 11999627
Electro-oculogram in vitamin A deficiency associated with cystic fibrosis. Short communication.
Leguire LE, Pappa KS, McGregor ML, Rogers GL, Bremer DL
Ophthalmic Paediatr Genet 1992 Sep;13(3):187-9. doi: 10.3109/13816819209046488. PMID: 1484697
Clinical implications of reported timolol-induced side effects.
Levine L
Am J Optom Physiol Opt 1982 Jun;59(6):523-8. doi: 10.1097/00006324-198206000-00014. PMID: 6125102

Prognosis

Non-syndromic OTX2-associated pattern dystrophy: a 10-year multimodal imaging study.
Ramakrishnan P, Kenworthy MK, Alexis JA, Thompson JA, Lamey TM, Chen FK
Doc Ophthalmol 2024 Oct;149(2):115-123. Epub 2024 Jul 18 doi: 10.1007/s10633-024-09983-w. PMID: 39023660Free PMC Article
Follow-up of a case of vitelliform macular dystrophy over an 8-year period.
Huang S, Wu L, Wen F, Luo G, Jiang F
Eye Sci 2014 Sep;29(3):165-9. PMID: 26011973

Clinical prediction guides

The effects of gender and age on the range of the normal human electro-oculogram.
Thavikulwat AT, Lopez P, Caruso RC, Jeffrey BG
Doc Ophthalmol 2015 Dec;131(3):177-88. Epub 2015 Oct 16 doi: 10.1007/s10633-015-9514-x. PMID: 26474906Free PMC Article
Follow-up of a case of vitelliform macular dystrophy over an 8-year period.
Huang S, Wu L, Wen F, Luo G, Jiang F
Eye Sci 2014 Sep;29(3):165-9. PMID: 26011973
Effect of docosahexaenoic acid supplementation on the macular function of patients with Best vitelliform macular dystrophy: randomized clinical trial.
Lee TK, Clandinin MT, Hébert M, MacDonald IM
Can J Ophthalmol 2010 Oct;45(5):514-9. doi: 10.3129/i10-028. PMID: 20847757

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