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Choroid plexus cancer

MedGen UID:
138053
•Concept ID:
C0346289
•
Neoplastic Process
Synonyms: cancer of choroid plexus; choroid plexus cancer; Malignant Choroid Plexus Neoplasm; malignant choroid plexus neoplasm; Malignant Choroid Plexus Neoplasms; malignant choroid plexus neoplasms; Malignant Choroid Plexus Tumor; malignant choroid plexus tumor; Malignant Choroid Plexus Tumors; malignant choroid plexus tumors; malignant choroid plexus tumour; malignant choroid plexus tumours; Malignant neoplasm of choroid plexus; Malignant Neoplasm of Choroid Plexus; malignant neoplasm of choroid plexus; Malignant Neoplasm of the Choroid Plexus; malignant neoplasm of the choroid plexus; Malignant tumor of choroid plexus; Malignant Tumor of Choroid Plexus; malignant tumor of choroid plexus; Malignant Tumor of the Choroid Plexus; malignant tumor of the choroid plexus; malignant tumour of choroid plexus; malignant tumour of the choroid plexus
SNOMED CT: Malignant tumor of choroid plexus (188292007); Malignant neoplasm of choroid plexus (188292007)
 
Monarch Initiative: MONDO:0002681

Definition

A malignant neoplasm that arises from the choroid plexus. The vast majority are carcinomas. [from NCI]

Professional guidelines

PubMed

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: [email protected], Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Triple intraventricular chemotherapy for treatment of relapsed choroid plexus carcinoma.
Lau G, Drummond J, Zhukova N, Wood P, Janson L
Pediatr Blood Cancer 2021 Sep;68(9):e29094. Epub 2021 May 18 doi: 10.1002/pbc.29094. PMID: 34003555
Prenatal diagnosis of choroid plexus cysts.
Ricketts NE, Lowe EM, Patel NB
Lancet 1987 Jan 24;1(8526):213-4. doi: 10.1016/s0140-6736(87)90022-5. PMID: 2880033

Recent clinical studies

Etiology

Management of Intraventricular Meningiomas.
Bamimore MA, Marenco-Hillembrand L, Ravindran K, Agyapong D, Greco E, Middlebrooks EH, Chaichana KL
Neurosurg Clin N Am 2023 Jul;34(3):403-415. Epub 2023 Apr 18 doi: 10.1016/j.nec.2023.02.005. PMID: 37210129
Less common intraparenchymal tumors.
Ganz JC
Prog Brain Res 2022;268(1):303-314. Epub 2021 Dec 14 doi: 10.1016/bs.pbr.2021.10.038. PMID: 35074087
Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: [email protected], Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
WHO 2016 Classification of gliomas.
Wesseling P, Capper D
Neuropathol Appl Neurobiol 2018 Feb;44(2):139-150. doi: 10.1111/nan.12432. PMID: 28815663
Extraparenchymal Lesions in Pediatric Patients.
Tenenbaum M
Neuroimaging Clin N Am 2017 Feb;27(1):123-134. doi: 10.1016/j.nic.2016.08.005. PMID: 27889019

Diagnosis

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: [email protected], Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Current management of choroid plexus carcinomas.
Sun MZ, Oh MC, Ivan ME, Kaur G, Safaee M, Kim JM, Phillips JJ, Auguste KI, Parsa AT
Neurosurg Rev 2014 Apr;37(2):179-92; discussion 192. Epub 2013 Sep 26 doi: 10.1007/s10143-013-0499-1. PMID: 24068529
Controversial ultrasound findings.
Rochon M, Eddleman K
Obstet Gynecol Clin North Am 2004 Mar;31(1):61-99. doi: 10.1016/S0889-8545(03)00123-2. PMID: 15062448
Nonmalignant pediatric brain tumors.
Rashidi M, DaSilva VR, Minagar A, Rutka JT
Curr Neurol Neurosci Rep 2003 May;3(3):200-5. doi: 10.1007/s11910-003-0079-9. PMID: 12691624
Hydrocephalus.
Paine RS
Pediatr Clin North Am 1967 Nov;14(4):779-96. doi: 10.1016/s0031-3955(16)32055-7. PMID: 4875462

Therapy

Preclinical and pilot clinical evaluation of a small-molecule carbonic anhydrase IX targeting PET tracer in clear cell renal cell carcinoma.
Zhu W, Li X, Zheng G, Bai C, Ji Z, Zhang H, Xing H, Zhang Y, Huo L
Eur J Nucl Med Mol Imaging 2023 Aug;50(10):3116-3125. Epub 2023 May 29 doi: 10.1007/s00259-023-06248-7. PMID: 37246998
Choroid plexus-CSF-targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy.
Jang A, Petrova B, Cheong TC, Zawadzki ME, Jones JK, Culhane AJ, Shipley FB, Chiarle R, Wong ET, Kanarek N, Lehtinen MK
Neuron 2022 Oct 19;110(20):3288-3301.e8. Epub 2022 Sep 6 doi: 10.1016/j.neuron.2022.08.009. PMID: 36070751Free PMC Article
Fetal surgery for spina bifida.
Dewan MC, Wellons JC
J Neurosurg Pediatr 2019 Aug 1;24(2):105-114. doi: 10.3171/2019.4.PEDS18383. PMID: 31370010
Intra-axial brain tumors.
Rapalino O, Batchelor T, González RG
Handb Clin Neurol 2016;135:253-274. doi: 10.1016/B978-0-444-53485-9.00014-3. PMID: 27432670
Hydrocephalus.
Paine RS
Pediatr Clin North Am 1967 Nov;14(4):779-96. doi: 10.1016/s0031-3955(16)32055-7. PMID: 4875462

Prognosis

Brain macrophage senescence in glioma.
Li L, Zhang T, Xiao M, Lu Y, Gao L
Semin Cancer Biol 2024 Sep;104-105:46-60. Epub 2024 Aug 2 doi: 10.1016/j.semcancer.2024.07.005. PMID: 39098625
Brain macrophage development, diversity and dysregulation in health and disease.
Silvin A, Qian J, Ginhoux F
Cell Mol Immunol 2023 Nov;20(11):1277-1289. Epub 2023 Jun 26 doi: 10.1038/s41423-023-01053-6. PMID: 37365324Free PMC Article
Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis.
Boire A, Zou Y, Shieh J, Macalinao DG, Pentsova E, Massagué J
Cell 2017 Mar 9;168(6):1101-1113.e13. doi: 10.1016/j.cell.2017.02.025. PMID: 28283064Free PMC Article
Choroid plexus carcinoma.
Chopra K, Iyer S, Matta SK, Gupta A, Malhotra V
Indian Pediatr 1996 May;33(5):420-2. PMID: 8979596
Uncommon brain tumors.
Schiff D, Wen PY
Neurol Clin 1995 Nov;13(4):953-74. PMID: 8584006

Clinical prediction guides

Border-associated macrophages in the central nervous system.
Sun R, Jiang H
J Neuroinflammation 2024 Mar 13;21(1):67. doi: 10.1186/s12974-024-03059-x. PMID: 38481312Free PMC Article
Management of Intraventricular Meningiomas.
Bamimore MA, Marenco-Hillembrand L, Ravindran K, Agyapong D, Greco E, Middlebrooks EH, Chaichana KL
Neurosurg Clin N Am 2023 Jul;34(3):403-415. Epub 2023 Apr 18 doi: 10.1016/j.nec.2023.02.005. PMID: 37210129
Fetal surgery for spina bifida.
Dewan MC, Wellons JC
J Neurosurg Pediatr 2019 Aug 1;24(2):105-114. doi: 10.3171/2019.4.PEDS18383. PMID: 31370010
Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis.
Boire A, Zou Y, Shieh J, Macalinao DG, Pentsova E, Massagué J
Cell 2017 Mar 9;168(6):1101-1113.e13. doi: 10.1016/j.cell.2017.02.025. PMID: 28283064Free PMC Article
Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers.
Bougeard G, Renaux-Petel M, Flaman JM, Charbonnier C, Fermey P, Belotti M, Gauthier-Villars M, Stoppa-Lyonnet D, Consolino E, Brugières L, Caron O, Benusiglio PR, Bressac-de Paillerets B, Bonadona V, Bonaïti-Pellié C, Tinat J, Baert-Desurmont S, Frebourg T
J Clin Oncol 2015 Jul 20;33(21):2345-52. Epub 2015 May 26 doi: 10.1200/JCO.2014.59.5728. PMID: 26014290

Recent systematic reviews

Symptomatic intraventricular choroid plexus cysts. Illustrative case and systematic review.
Stanishevskiy A, Gavrilov G, Svistov D, Cherebillo V, Kurnukhina M
Neurosurg Rev 2023 Oct 6;46(1):264. doi: 10.1007/s10143-023-02176-0. PMID: 37801091
Isolated choroid plexus cysts and health and developmental outcomes in childhood and adolescence - A systematic review.
Singal K, Adamczyk K, Hurt L, Woolner A, Paranjothy S
Eur J Obstet Gynecol Reprod Biol 2023 Nov;290:115-122. Epub 2023 Sep 16 doi: 10.1016/j.ejogrb.2023.09.013. PMID: 37778251
Metastasis of the choroid plexuses: A systematic review of the literature and case illustration.
Garrido E, Alqahtani K, Lozouet M, Derrey S, Gilard V
Neurochirurgie 2023 Mar;69(2):101412. Epub 2023 Jan 14 doi: 10.1016/j.neuchi.2023.101412. PMID: 36649887
Pediatric choroid plexus papilloma arising from the cerebellopontine angle: systematic review with illustrative case.
Gaddi MJS, Lappay JI, Chan KIP, Pascual JSG, Salonga AEM
Childs Nerv Syst 2021 Mar;37(3):799-807. Epub 2020 Sep 26 doi: 10.1007/s00381-020-04896-w. PMID: 32980905
Psammomatous Cavernous Malformation Presenting as Drug-Resistant Epilepsy: Case Illustration and Review of Literature.
Sharma K, Kalakoti P, Shaughnessy JE, De La Cruz N, Dossani RH, Zhu P, Gonzalez-Toledo E, Ledbetter C, Pinskton JB, Nanda A, Riel-Romero RM, Minagar A, Notarianni C, Sun H
World Neurosurg 2016 Sep;93:120-6. Epub 2016 Jun 7 doi: 10.1016/j.wneu.2016.05.093. PMID: 27283183

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