U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ciliary body melanoma

MedGen UID:
138062
•Concept ID:
C0346379
•
Neoplastic Process
Synonyms: Body Melanoma, Ciliary; Ciliary Body Melanoma; Ciliary Body Melanomas; Melanoma, Ciliary Body
SNOMED CT: Ciliary body melanoma (255015006); Malignant melanoma of ciliary body (255015006)
 
HPO: HP:0012055
Monarch Initiative: MONDO:0003912

Definition

Malignant tumor of melanocytes of the ciliary body. [from HPO]

Professional guidelines

PubMed

Robotic CyberKnife Radiosurgery for the Treatment of Choroidal and Ciliary Body Melanoma.
Liegl R, Schmelter V, Fuerweger C, Ehret F, Priglinger S, Muacevic A, Foerster P
Am J Ophthalmol 2023 Jun;250:177-185. Epub 2023 Jan 13 doi: 10.1016/j.ajo.2022.12.021. PMID: 36642391
Ciliary body melanoma treatment by stereotactic radiosurgery.
Furdová A, Juhas J, Šramka M, Králik G
Cesk Slov Oftalmol 2018 Spring;73(5-6):204-210. PMID: 30541301
The treatment of ciliary body melanoma by beta radiation.
Foerster MH, Wessing A, Meyer-Schwickerath G
Trans Ophthalmol Soc U K (1962) 1983;103 ( Pt 1):64-7. PMID: 6581638

Recent clinical studies

Etiology

The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group.
van Poppelen NM, Cassoux N, Turunen JA, Naus NC, Verdijk RM, Vaarwater J, Cohen V, Papastefanou VP, Kiratli H, Saakyan SV, Tsygankov AY, Rospond-Kubiak I, Mudhar HS, Salvi SM, Kiilgaard JF, Heegaard S, Moulin AP, Saornil MA, Garciá-Alvarez C, Fili M, Eide NA, Meyer P, Kivelä TT, de Klein A, Kilic E, Al-Jamal RT
Invest Ophthalmol Vis Sci 2024 Apr 1;65(4):12. doi: 10.1167/iovs.65.4.12. PMID: 38573618Free PMC Article
Robotic CyberKnife Radiosurgery for the Treatment of Choroidal and Ciliary Body Melanoma.
Liegl R, Schmelter V, Fuerweger C, Ehret F, Priglinger S, Muacevic A, Foerster P
Am J Ophthalmol 2023 Jun;250:177-185. Epub 2023 Jan 13 doi: 10.1016/j.ajo.2022.12.021. PMID: 36642391
Robotic CyberKnife Radiosurgery for Ciliary Body Melanoma.
Liegl R, Schmelter V, Fuerweger C, Foerster MH, Muacevic A, Priglinger SG, Schaller UC, Foerster P
Ophthalmol Retina 2020 Sep;4(9):954-956. Epub 2020 Apr 20 doi: 10.1016/j.oret.2020.03.031. PMID: 32595095
Ciliary body melanoma treatment by stereotactic radiosurgery.
Furdová A, Juhas J, Šramka M, Králik G
Cesk Slov Oftalmol 2018 Spring;73(5-6):204-210. PMID: 30541301
An Update on Oculodermal Melanocytosis and Rare Associated Conditions.
Plateroti AM, Scavella V, Abdolrahimzadeh B, Plateroti R, Rahimi S
Semin Ophthalmol 2017;32(4):524-528. Epub 2016 Apr 15 doi: 10.3109/08820538.2015.1118133. PMID: 27083007

Diagnosis

The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group.
van Poppelen NM, Cassoux N, Turunen JA, Naus NC, Verdijk RM, Vaarwater J, Cohen V, Papastefanou VP, Kiratli H, Saakyan SV, Tsygankov AY, Rospond-Kubiak I, Mudhar HS, Salvi SM, Kiilgaard JF, Heegaard S, Moulin AP, Saornil MA, Garciá-Alvarez C, Fili M, Eide NA, Meyer P, Kivelä TT, de Klein A, Kilic E, Al-Jamal RT
Invest Ophthalmol Vis Sci 2024 Apr 1;65(4):12. doi: 10.1167/iovs.65.4.12. PMID: 38573618Free PMC Article
Robotic CyberKnife Radiosurgery for Ciliary Body Melanoma.
Liegl R, Schmelter V, Fuerweger C, Foerster MH, Muacevic A, Priglinger SG, Schaller UC, Foerster P
Ophthalmol Retina 2020 Sep;4(9):954-956. Epub 2020 Apr 20 doi: 10.1016/j.oret.2020.03.031. PMID: 32595095
Ciliary body melanoma treatment by stereotactic radiosurgery.
Furdová A, Juhas J, Šramka M, Králik G
Cesk Slov Oftalmol 2018 Spring;73(5-6):204-210. PMID: 30541301
Ciliary body melanoma manifesting as unilateral ocular hypertension and early cataract.
Siempis T, McTaggart Y, Sidiki SS
Clin Exp Optom 2018 Mar;101(2):305-307. Epub 2017 Oct 11 doi: 10.1111/cxo.12610. PMID: 29024006
Ciliary body melanoma simulating multiple iris cysts.
Krohn J, Arnes J, Rødahl E
Arch Ophthalmol 2007 Mar;125(3):428-9. doi: 10.1001/archopht.125.3.428. PMID: 17353422

Therapy

Robotic CyberKnife Radiosurgery for the Treatment of Choroidal and Ciliary Body Melanoma.
Liegl R, Schmelter V, Fuerweger C, Ehret F, Priglinger S, Muacevic A, Foerster P
Am J Ophthalmol 2023 Jun;250:177-185. Epub 2023 Jan 13 doi: 10.1016/j.ajo.2022.12.021. PMID: 36642391
Determinants of Long-Term Survival in Metastatic Choroidal and Ciliary Body Melanoma.
Rantala ES, Parrozzani R, Hernberg MM, Chiarion-Sileni V, Kivelä TT, Midena E
Am J Ophthalmol 2023 Feb;246:258-272. Epub 2022 Nov 1 doi: 10.1016/j.ajo.2022.10.017. PMID: 36328199
Tadalafil-induced subretinal and choroidal hemorrhage in a patient with an unsuspected uveal (choroidal and ciliary body) melanoma.
Abramson DH, Rollins IS, Lin A, Odell P, Folberg R
Arch Ophthalmol 2006 Jul;124(7):1058-60. doi: 10.1001/archopht.124.7.1058. PMID: 16832036
Mascara and eyelining tattoos: MRI artifacts.
Weiss RA, Saint-Louis LA, Haik BG, McCord CD, Taveras JL
Ann Ophthalmol 1989 Apr;21(4):129-31. PMID: 2729816
The treatment of ciliary body melanoma by beta radiation.
Foerster MH, Wessing A, Meyer-Schwickerath G
Trans Ophthalmol Soc U K (1962) 1983;103 ( Pt 1):64-7. PMID: 6581638

Prognosis

The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group.
van Poppelen NM, Cassoux N, Turunen JA, Naus NC, Verdijk RM, Vaarwater J, Cohen V, Papastefanou VP, Kiratli H, Saakyan SV, Tsygankov AY, Rospond-Kubiak I, Mudhar HS, Salvi SM, Kiilgaard JF, Heegaard S, Moulin AP, Saornil MA, Garciá-Alvarez C, Fili M, Eide NA, Meyer P, Kivelä TT, de Klein A, Kilic E, Al-Jamal RT
Invest Ophthalmol Vis Sci 2024 Apr 1;65(4):12. doi: 10.1167/iovs.65.4.12. PMID: 38573618Free PMC Article
Determinants of Long-Term Survival in Metastatic Choroidal and Ciliary Body Melanoma.
Rantala ES, Parrozzani R, Hernberg MM, Chiarion-Sileni V, Kivelä TT, Midena E
Am J Ophthalmol 2023 Feb;246:258-272. Epub 2022 Nov 1 doi: 10.1016/j.ajo.2022.10.017. PMID: 36328199
Robotic CyberKnife Radiosurgery for Ciliary Body Melanoma.
Liegl R, Schmelter V, Fuerweger C, Foerster MH, Muacevic A, Priglinger SG, Schaller UC, Foerster P
Ophthalmol Retina 2020 Sep;4(9):954-956. Epub 2020 Apr 20 doi: 10.1016/j.oret.2020.03.031. PMID: 32595095
Intravitreal air bubble during exoresection of an iris-ciliary body melanoma.
Relimpio-López MI, Garrido-Hermosilla AM
Surg Oncol 2019 Jun;29:157-158. Epub 2019 May 14 doi: 10.1016/j.suronc.2019.05.008. PMID: 31196482
Unusual course of a ciliary body melanoma.
Matas BR
Am J Ophthalmol 1971 Sep;72(3):592-4. doi: 10.1016/0002-9394(71)90856-7. PMID: 5568610

Clinical prediction guides

The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group.
van Poppelen NM, Cassoux N, Turunen JA, Naus NC, Verdijk RM, Vaarwater J, Cohen V, Papastefanou VP, Kiratli H, Saakyan SV, Tsygankov AY, Rospond-Kubiak I, Mudhar HS, Salvi SM, Kiilgaard JF, Heegaard S, Moulin AP, Saornil MA, Garciá-Alvarez C, Fili M, Eide NA, Meyer P, Kivelä TT, de Klein A, Kilic E, Al-Jamal RT
Invest Ophthalmol Vis Sci 2024 Apr 1;65(4):12. doi: 10.1167/iovs.65.4.12. PMID: 38573618Free PMC Article
Cytogenetic Abnormalities for Predicting the Risk of Metastases in Choroidal and Ciliary Body Melanoma.
Chao AN, Rose K, Racher H, Altomare F, Krema H
Invest Ophthalmol Vis Sci 2023 Jan 3;64(1):15. doi: 10.1167/iovs.64.1.15. PMID: 36656566Free PMC Article
Determinants of Long-Term Survival in Metastatic Choroidal and Ciliary Body Melanoma.
Rantala ES, Parrozzani R, Hernberg MM, Chiarion-Sileni V, Kivelä TT, Midena E
Am J Ophthalmol 2023 Feb;246:258-272. Epub 2022 Nov 1 doi: 10.1016/j.ajo.2022.10.017. PMID: 36328199
Intravitreal air bubble during exoresection of an iris-ciliary body melanoma.
Relimpio-López MI, Garrido-Hermosilla AM
Surg Oncol 2019 Jun;29:157-158. Epub 2019 May 14 doi: 10.1016/j.suronc.2019.05.008. PMID: 31196482
Iridocyclectomy for melanomas of the ciliary body: a follow-up study of pathology and surgical morbidity.
Forrest AW, Keyser RB, Spencer WH
Ophthalmology 1978 Dec;85(12):1237-49. doi: 10.1016/s0161-6420(78)35560-3. PMID: 745829

Recent systematic reviews

The long-term prognosis of patients with untreated primary uveal melanoma: A systematic review and meta-analysis.
Stålhammar G, Gill VT
Crit Rev Oncol Hematol 2022 Apr;172:103652. Epub 2022 Mar 15 doi: 10.1016/j.critrevonc.2022.103652. PMID: 35304261
Secondary glaucoma as initial manifestation of ring melanoma: a case report and review of literature.
Zhao M, Mu Y, Dang Y, Zhu Y
Int J Clin Exp Pathol 2014;7(11):8163-9. Epub 2014 Oct 15 PMID: 25550867Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...