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Posterior Tongue Carcinoma

MedGen UID:
138066
•Concept ID:
C0346564
•
Neoplastic Process
Synonyms: Base of the Tongue Carcinoma; Base of Tongue Carcinoma; Carcinoma of base of tongue; Carcinoma of Base of Tongue; Carcinoma of Posterior Tongue; Carcinoma of the Base of the Tongue; Carcinoma of the Posterior Tongue
SNOMED CT: Carcinoma of base of tongue (271943005)

Definition

A carcinoma that arises from the base of the tongue. Representative examples include squamous cell carcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma. [from NCI]

Professional guidelines

PubMed

Update on Pathologic Conditions, Imaging Findings, Prevention, and Management of Human Papillomavirus-related Neoplasms.
Katabathina VS, Ghannam S, Chen M, Desalme B, Gabos R, Emejulu I, Sandhu PK, Valente P, Dasyam AK, Prasad SR
Radiographics 2024 Aug;44(8):e230179. doi: 10.1148/rg.230179. PMID: 39024173
Psychosocial Oncology: Optimizing Outcomes through Interdisciplinary Care in Head and Neck Oncology.
Henry M
Curr Oncol 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501. PMID: 37504361Free PMC Article
Oral cavity squamous cell carcinoma: role of pretreatment imaging and its influence on management.
Arya S, Rane P, Deshmukh A
Clin Radiol 2014 Sep;69(9):916-30. Epub 2014 Jun 5 doi: 10.1016/j.crad.2014.04.013. PMID: 24908285

Recent clinical studies

Etiology

Prognostic Value of Anteroposterior Extension in Oral Tongue and Floor Squamous Cell Carcinoma.
Contro G, Sordi A, Taboni S, Citterio M, Ruaro A, De Lucia G, Pinacoli A, Carobbio ALC, Montalto N, Ramacciotti G, Grammatica A, Marioni G, Zanoletti E, Maroldi R, Piazza C, Mattavelli D, Nicolai P, Ferrari M
JAMA Otolaryngol Head Neck Surg 2024 Feb 1;150(2):142-150. doi: 10.1001/jamaoto.2023.3809. PMID: 38153706Free PMC Article
Case series report: radiation-induced oropharyngeal carcinoma.
Salman S, Doweck I, Taha T, Billan S
Anticancer Drugs 2023 Feb 1;34(2):325-331. Epub 2022 Nov 15 doi: 10.1097/CAD.0000000000001411. PMID: 36730617
Classification of tongue cancer resection and treatment algorithm.
Mannelli G, Arcuri F, Agostini T, Innocenti M, Raffaini M, Spinelli G
J Surg Oncol 2018 Apr;117(5):1092-1099. Epub 2018 Feb 12 doi: 10.1002/jso.24991. PMID: 29432642
Distant metastases from salivary glands cancer.
Bradley PJ
ORL J Otorhinolaryngol Relat Spec 2001 Jul-Aug;63(4):233-42. doi: 10.1159/000055748. PMID: 11408820
Median labiomandibular glossotomy.
Wessberg GA, Hill SC, McBride KL
Int J Oral Surg 1981 Oct;10(5):333-7. doi: 10.1016/s0300-9785(81)80030-0. PMID: 6807920

Diagnosis

Case series report: radiation-induced oropharyngeal carcinoma.
Salman S, Doweck I, Taha T, Billan S
Anticancer Drugs 2023 Feb 1;34(2):325-331. Epub 2022 Nov 15 doi: 10.1097/CAD.0000000000001411. PMID: 36730617
Transoral endoscopic examination of head and neck region.
Hamada K, Ishihara R, Yamasaki Y, Akasaka T, Arao M, Iwatsubo T, Shichijo S, Matsuura N, Nakahira H, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Kawahara Y, Okada H
Dig Endosc 2018 Jul;30(4):516-521. Epub 2018 Apr 26 doi: 10.1111/den.13071. PMID: 29637617
Mucoepidermoid carcinoma of the posterior-lateral border of tongue: a rare presentation.
Mathew L, Janardhanan M, Suresh R, Savithri V
BMJ Case Rep 2017 Oct 24;2017 doi: 10.1136/bcr-2017-221521. PMID: 29066652Free PMC Article
Adenoid cystic carcinoma of the base of the tongue metastasizing to the scalp.
Saco M, Howe N, Jukic DM, Muro-Cacho C
Dermatol Online J 2014 Mar 17;20(3) PMID: 24656266
The thyroid and parathyroid glands. CT and MR imaging and correlation with pathology and clinical findings.
Weber AL, Randolph G, Aksoy FG
Radiol Clin North Am 2000 Sep;38(5):1105-29. doi: 10.1016/s0033-8389(05)70224-4. PMID: 11054972

Therapy

Management of a glottic squamous cell carcinoma with cutaneous metastasis.
Alkan A, Kayış D, Çelik SY, Uylaş S, Demir Pektaş S, Oral Tapan Ö, Gökdoğan O, Türkkan G, Genç S, Tanrıverdi Ö
J Oncol Pharm Pract 2020 Sep;26(6):1495-1498. Epub 2020 Feb 6 doi: 10.1177/1078155219900782. PMID: 32028840
Volumetric changes in pharyngeal structures following head and neck cancer chemoradiation therapy.
Hinther A, Samson N, Lau H, Quon H, Banerjee R, Lysack JT, Grendarova P, Matthews TW, Randall DR
Laryngoscope 2020 Mar;130(3):597-602. Epub 2019 Jul 1 doi: 10.1002/lary.28164. PMID: 31260128
A phase 1 trial of Vorinostat in combination with concurrent chemoradiation therapy in the treatment of advanced staged head and neck squamous cell carcinoma.
Teknos TN, Grecula J, Agrawal A, Old MO, Ozer E, Carrau R, Kang S, Rocco J, Blakaj D, Diavolitsis V, Kumar B, Kumar P, Pan Q, Palettas M, Wei L, Baiocchi R, Savvides P
Invest New Drugs 2019 Aug;37(4):702-710. Epub 2018 Dec 19 doi: 10.1007/s10637-018-0696-4. PMID: 30569244
Cine-MRI swallowing evaluation after tongue reconstruction.
Hartl DM, Kolb F, Bretagne E, Bidault F, Sigal R
Eur J Radiol 2010 Jan;73(1):108-13. Epub 2008 Dec 16 doi: 10.1016/j.ejrad.2008.10.005. PMID: 19091505
Carcinoma of the posterior tongue treated with radiation.
MARTIN CL, MARTIN JA
Radiology 1956 Jun;66(6):835-41. doi: 10.1148/66.6.835. PMID: 13323324

Prognosis

Update on Pathologic Conditions, Imaging Findings, Prevention, and Management of Human Papillomavirus-related Neoplasms.
Katabathina VS, Ghannam S, Chen M, Desalme B, Gabos R, Emejulu I, Sandhu PK, Valente P, Dasyam AK, Prasad SR
Radiographics 2024 Aug;44(8):e230179. doi: 10.1148/rg.230179. PMID: 39024173
Classification of tongue cancer resection and treatment algorithm.
Mannelli G, Arcuri F, Agostini T, Innocenti M, Raffaini M, Spinelli G
J Surg Oncol 2018 Apr;117(5):1092-1099. Epub 2018 Feb 12 doi: 10.1002/jso.24991. PMID: 29432642
Adenoid cystic carcinoma of the base of the tongue metastasizing to the scalp.
Saco M, Howe N, Jukic DM, Muro-Cacho C
Dermatol Online J 2014 Mar 17;20(3) PMID: 24656266
Distant metastasis of parotid gland tumors.
Schwentner I, Obrist P, Thumfart W, Sprinzl G
Acta Otolaryngol 2006 Apr;126(4):340-5. doi: 10.1080/00016480500401035. PMID: 16608783
Median labiomandibular glossotomy.
Wessberg GA, Hill SC, McBride KL
Int J Oral Surg 1981 Oct;10(5):333-7. doi: 10.1016/s0300-9785(81)80030-0. PMID: 6807920

Clinical prediction guides

Update on Pathologic Conditions, Imaging Findings, Prevention, and Management of Human Papillomavirus-related Neoplasms.
Katabathina VS, Ghannam S, Chen M, Desalme B, Gabos R, Emejulu I, Sandhu PK, Valente P, Dasyam AK, Prasad SR
Radiographics 2024 Aug;44(8):e230179. doi: 10.1148/rg.230179. PMID: 39024173
Speech disorders in patients with Tongue squamous cell carcinoma: A longitudinal observational study based on a questionnaire and acoustic analysis.
Guo K, Xiao Y, Deng W, Zhao G, Zhang J, Liang Y, Yang L, Liao G
BMC Oral Health 2023 Apr 1;23(1):192. doi: 10.1186/s12903-023-02888-1. PMID: 37005608Free PMC Article
Prevalence and prognostic impact of retropharyngeal lymph nodes metastases in oropharyngeal squamous cell carcinoma: Meta-analysis of published literature.
Tirelli G, Gardenal N, Zanelli E, Borsetto D, Phillips V, Marcuzzo AV, Fussey J, Polesel J, Boscolo-Rizzo P
Head Neck 2022 Oct;44(10):2265-2276. Epub 2022 Aug 1 doi: 10.1002/hed.27166. PMID: 35913029Free PMC Article
Transoral endoscopic examination of head and neck region.
Hamada K, Ishihara R, Yamasaki Y, Akasaka T, Arao M, Iwatsubo T, Shichijo S, Matsuura N, Nakahira H, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Kawahara Y, Okada H
Dig Endosc 2018 Jul;30(4):516-521. Epub 2018 Apr 26 doi: 10.1111/den.13071. PMID: 29637617
Cine-MRI swallowing evaluation after tongue reconstruction.
Hartl DM, Kolb F, Bretagne E, Bidault F, Sigal R
Eur J Radiol 2010 Jan;73(1):108-13. Epub 2008 Dec 16 doi: 10.1016/j.ejrad.2008.10.005. PMID: 19091505

Recent systematic reviews

Prevalence and prognostic impact of retropharyngeal lymph nodes metastases in oropharyngeal squamous cell carcinoma: Meta-analysis of published literature.
Tirelli G, Gardenal N, Zanelli E, Borsetto D, Phillips V, Marcuzzo AV, Fussey J, Polesel J, Boscolo-Rizzo P
Head Neck 2022 Oct;44(10):2265-2276. Epub 2022 Aug 1 doi: 10.1002/hed.27166. PMID: 35913029Free PMC Article

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