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Localized lipodystrophy

MedGen UID:
1385527
Concept ID:
C4329999
Disease or Syndrome
Synonym: Atypical lipodystrophy
SNOMED CT: Localized lipodystrophy (788978004)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
Concept ID:
CN307042
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
 
Monarch Initiative: MONDO:0019194
Orphanet: ORPHA79088

Definition

A rare group of acquired lipodystrophies that are characterized by loss of subcutaneous tissue from generally small regions of the body, either single or multiple areas, and are not typically associated with metabolic complications. Some cases may involve lipohypertrophy (insulin). This group includes pressure-induced localized lipoatrophy, drug-induced localized lipodystrophy, panniculitis- induced localized lipodystrophy, centrifugal lipodystrophy, and idiopathic localized lipodystrophy. [from ORDO]

Professional guidelines

PubMed

Jagdeo J, Ho D, Lo A, Carruthers A
J Am Acad Dermatol 2015 Dec;73(6):1040-54.e14. Epub 2015 Oct 23 doi: 10.1016/j.jaad.2015.08.040. PMID: 26481056
Kadouch JA, van Rozelaar L, Karim RB, Hoekzema R
Int J STD AIDS 2013 Sep;24(9):685-94. Epub 2013 Jul 19 doi: 10.1177/0956462412474539. PMID: 23970569
Patrick AW, Williams G
Drug Saf 1993 Jun;8(6):427-44. doi: 10.2165/00002018-199308060-00004. PMID: 8329148

Recent clinical studies

Etiology

Gdynia HJ, Weydt P, Ernst A, Klein S, Sperfeld AD, Riecker A
Eur J Med Res 2009 May 14;14(5):228-30. doi: 10.1186/2047-783x-14-5-228. PMID: 19541581Free PMC Article
Tay YK, Ong BH
Pediatr Dermatol 2002 Jul-Aug;19(4):365-7. doi: 10.1046/j.1525-1470.2002.00102.x. PMID: 12220289

Diagnosis

Tay YK, Ong BH
Pediatr Dermatol 2002 Jul-Aug;19(4):365-7. doi: 10.1046/j.1525-1470.2002.00102.x. PMID: 12220289

Therapy

Gdynia HJ, Weydt P, Ernst A, Klein S, Sperfeld AD, Riecker A
Eur J Med Res 2009 May 14;14(5):228-30. doi: 10.1186/2047-783x-14-5-228. PMID: 19541581Free PMC Article

Prognosis

Tay YK, Ong BH
Pediatr Dermatol 2002 Jul-Aug;19(4):365-7. doi: 10.1046/j.1525-1470.2002.00102.x. PMID: 12220289

Supplemental Content

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