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Vitreomacular traction

MedGen UID:
1391762
•Concept ID:
C3161192
•
Disease or Syndrome
Synonym: VMT
 
HPO: HP:0031151

Definition

Vitreomacular traction is characterized by anomalous posterior vitreous detachment accompanied by anatomic distortion of the fovea, which may include pseudocysts, macular schisis, cystoid macular edema, and subretinal fluid. Vitreomacular traction can be subclassified by the diameter of vitreous attachment to the macular surface as measured by OCT, with attachment of 1500 micrometers or less defined as focal and attachment of more than 1500 micrometers as broad. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVitreomacular traction

Professional guidelines

PubMed

Intravitreal ocriplasmin: A breakthrough in the treatment of vitreomacular traction?
Mec-Słomska AE, Adamiec-Mroczek J, Kuźmicz E, Misiuk-Hojło M
Adv Clin Exp Med 2017 May-Jun;26(3):527-531. doi: 10.17219/acem/62122. PMID: 28791829
Current Treatment Options for the Management of Vitreomacular Traction.
Dhoot DS, Hariprasad SM, Steinle NC
Ophthalmic Surg Lasers Imaging Retina 2017 May 1;48(5):374-377. doi: 10.3928/23258160-20170428-02. PMID: 28499047
Clinical management of vitreomacular traction.
Khan MA, Haller JA
Curr Opin Ophthalmol 2015 May;26(3):143-8. doi: 10.1097/ICU.0000000000000149. PMID: 25784108

Recent clinical studies

Etiology

INTRARETINAL HYPERREFLECTIVE LINES.
Amoroso F, Mrejen S, Pedinielli A, Tabary S, Souied EH, Gaudric A, Cohen SY
Retina 2021 Jan 1;41(1):82-92. doi: 10.1097/IAE.0000000000002806. PMID: 32251237
Clinical management of vitreomacular traction.
Khan MA, Haller JA
Curr Opin Ophthalmol 2015 May;26(3):143-8. doi: 10.1097/ICU.0000000000000149. PMID: 25784108
Vitreomacular traction syndrome: postoperative functional and anatomic outcomes.
Bottos J, Elizalde J, Rodrigues EB, Farah M, Maia M
Ophthalmic Surg Lasers Imaging Retina 2015 Feb;46(2):235-42. doi: 10.3928/23258160-20150213-14. PMID: 25707050
Vitreomacular traction syndrome.
Shao L, Wei W
Chin Med J (Engl) 2014;127(8):1566-71. PMID: 24762607
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995

Diagnosis

Non-vasogenic cystoid maculopathies.
Gaudric A, Audo I, Vignal C, Couturier A, Boulanger-Scemama É, Tadayoni R, Cohen SY
Prog Retin Eye Res 2022 Nov;91:101092. Epub 2022 Aug 1 doi: 10.1016/j.preteyeres.2022.101092. PMID: 35927124
Miscellaneous.
Creuzot-Garcher C
Dev Ophthalmol 2017;58:220-237. Epub 2017 Mar 28 doi: 10.1159/000455283. PMID: 28351050
Vitreomacular traction syndrome.
Shao L, Wei W
Chin Med J (Engl) 2014;127(8):1566-71. PMID: 24762607
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995
Symptomatic vitreomacular adhesion.
Jackson TL, Nicod E, Simpson A, Angelis A, Grimaccia F, Kanavos P
Retina 2013 Sep;33(8):1503-11. doi: 10.1097/IAE.0b013e31829232fd. PMID: 23714857

Therapy

Pharmacotherapy of Vitreomacular Traction.
Wan R, Hong T, Tariq Y, Chang A
Curr Pharm Des 2018;24(41):4874-4881. doi: 10.2174/1381612825666190124102148. PMID: 30674252
Current Anti-Integrin Therapy for Ocular Disease.
Gonzalez-Salinas R, Hernández-Zimbrón LF, Gulias-Cañizo R, Sánchez-Vela MA, Ochoa-De La Paz L, Zamora R, Quiroz-Mercado H
Semin Ophthalmol 2018;33(5):634-642. Epub 2017 Oct 31 doi: 10.1080/08820538.2017.1388411. PMID: 29087767
Enzymatic Vitreolysis for Vitreomacular Traction in Diabetic Retinopathy.
Rizzo S, Bacherini D
Dev Ophthalmol 2017;60:160-164. Epub 2017 Apr 20 doi: 10.1159/000460275. PMID: 28427074
Macular edema. Miscellaneous.
Creuzot-Garcher C, Wolf S
Dev Ophthalmol 2010;47:183-198. Epub 2010 Aug 10 doi: 10.1159/000320081. PMID: 20703051
Enzymatic vitreous disruption.
Gandorfer A
Eye (Lond) 2008 Oct;22(10):1273-7. Epub 2008 Feb 22 doi: 10.1038/eye.2008.29. PMID: 18292784

Prognosis

INTRARETINAL HYPERREFLECTIVE LINES.
Amoroso F, Mrejen S, Pedinielli A, Tabary S, Souied EH, Gaudric A, Cohen SY
Retina 2021 Jan 1;41(1):82-92. doi: 10.1097/IAE.0000000000002806. PMID: 32251237
Surgical Management and Techniques.
Codenotti M, Iuliano L, Maestranzi G
Dev Ophthalmol 2017;60:143-159. Epub 2017 Apr 20 doi: 10.1159/000459702. PMID: 28427073
Miscellaneous.
Creuzot-Garcher C
Dev Ophthalmol 2017;58:220-237. Epub 2017 Mar 28 doi: 10.1159/000455283. PMID: 28351050
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995
Macular edema. Miscellaneous.
Creuzot-Garcher C, Wolf S
Dev Ophthalmol 2010;47:183-198. Epub 2010 Aug 10 doi: 10.1159/000320081. PMID: 20703051

Clinical prediction guides

Miscellaneous.
Creuzot-Garcher C
Dev Ophthalmol 2017;58:220-237. Epub 2017 Mar 28 doi: 10.1159/000455283. PMID: 28351050
Vitreomacular traction syndrome.
Shao L, Wei W
Chin Med J (Engl) 2014;127(8):1566-71. PMID: 24762607
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995
Symptomatic vitreomacular adhesion.
Jackson TL, Nicod E, Simpson A, Angelis A, Grimaccia F, Kanavos P
Retina 2013 Sep;33(8):1503-11. doi: 10.1097/IAE.0b013e31829232fd. PMID: 23714857
Macular edema. Miscellaneous.
Creuzot-Garcher C, Wolf S
Dev Ophthalmol 2010;47:183-198. Epub 2010 Aug 10 doi: 10.1159/000320081. PMID: 20703051

Recent systematic reviews

Ocriplasmin for treatment of vitreomacular traction and macular hole: A systematic literature review and individual participant data meta-analysis of randomized, controlled, double-masked trials.
Jackson TL, Haller J, Blot KH, Duchateau L, Lescrauwaet B
Surv Ophthalmol 2022 May-Jun;67(3):697-711. Epub 2021 Sep 2 doi: 10.1016/j.survophthal.2021.08.003. PMID: 34480895
Ocriplasmin use for vitreomacular traction and macular hole: A meta-analysis and comprehensive review on predictive factors for vitreous release and potential complications.
Chatziralli I, Theodossiadis G, Xanthopoulou P, Miligkos M, Sivaprasad S, Theodossiadis P
Graefes Arch Clin Exp Ophthalmol 2016 Jul;254(7):1247-56. Epub 2016 Apr 30 doi: 10.1007/s00417-016-3363-5. PMID: 27137631
Review of economic studies and budget impact analysis of ocriplasmin as a treatment of vitreomacular traction.
García-Pérez L, Abreu-González R, Pérez-Ramos J, García-Pérez S, Serrano-Aguilar P
Arch Soc Esp Oftalmol 2016 Jun;91(6):257-64. Epub 2016 Feb 24 doi: 10.1016/j.oftal.2016.01.022. PMID: 26920947
Vitrectomy for diabetic macular edema: a systematic review and meta-analysis.
Simunovic MP, Hunyor AP, Ho IV
Can J Ophthalmol 2014 Apr;49(2):188-95. doi: 10.1016/j.jcjo.2013.11.012. PMID: 24767227
Pars plana vitrectomy for vitreomacular traction syndrome: a systematic review and metaanalysis of safety and efficacy.
Jackson TL, Nicod E, Angelis A, Grimaccia F, Prevost AT, Simpson AR, Kanavos P
Retina 2013 Nov-Dec;33(10):2012-7. doi: 10.1097/IAE.0b013e3182a6b3e2. PMID: 24013261

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