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Postcricoid region cancer

MedGen UID:
141673
•Concept ID:
C0496769
•
Neoplastic Process
Synonyms: Malignant Neoplasm of Postcricoid Area; malignant neoplasm of postcricoid area; Malignant Neoplasm of the Postcricoid Area; malignant neoplasm of the postcricoid area; Malignant Postcricoid Neoplasm; malignant postcricoid neoplasm; Malignant Postcricoid Tumor; malignant postcricoid tumor; malignant postcricoid tumour; Malignant tumor of pharyngoesophageal junction; malignant tumor of pharyngoesophageal junction; Malignant Tumor of Postcricoid Area; malignant tumor of postcricoid area; Malignant tumor of postcricoid region; Malignant Tumor of the Postcricoid Area; malignant tumor of the postcricoid area; malignant tumour of pharyngoesophageal junction; malignant tumour of postcricoid area; malignant tumour of the postcricoid area; postcricoid region cancer
SNOMED CT: Malignant tumor of pharyngoesophageal junction (363400004); Malignant tumor of postcricoid region (363400004)
 
Monarch Initiative: MONDO:0004635

Definition

A primary or metastatic malignant neoplasm that affects the postcricoid region. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPostcricoid region cancer

Professional guidelines

PubMed

Clinicopathological factors influencing the outcomes of surgical treatment in patients with T4a hypopharyngeal cancer.
Kim SY, Rho YS, Choi EC, Kim MS, Woo JH, Lee DH, Chung EJ, Park MW, Kim DH, Joo YH
BMC Cancer 2017 Dec 29;17(1):904. doi: 10.1186/s12885-017-3880-6. PMID: 29284434Free PMC Article
Hypopharyngeal cancer: results of treatment based on radiation therapy and salvage surgery.
Godballe C, Jørgensen K, Hansen O, Bastholt L
Laryngoscope 2002 May;112(5):834-8. doi: 10.1097/00005537-200205000-00011. PMID: 12150614
The treatment of node negative squamous cell carcinoma of the postcricoid region.
Jones AS, McRae RD, Phillips DE, Hamilton J, Field JK, Husband D
J Laryngol Otol 1995 Feb;109(2):114-9. doi: 10.1017/s0022215100129433. PMID: 7706915

Recent clinical studies

Etiology

Individualized elective irradiation of the clinically node-negative neck in definitive radiotherapy for head and neck squamous cell carcinoma.
Kou J, Lin L, Jiao CY, Tian MQ, Zhou GQ, Jiang X, Ma J, Qi ZY, Lu Y, Sun Y
Cancer Commun (Lond) 2021 Apr;41(4):303-315. Epub 2021 Feb 26 doi: 10.1002/cac2.12145. PMID: 33636050Free PMC Article
Surgical management around the paratracheal area of hypopharyngeal cancer.
Tomioka T, Beppu T, Fujii T, Ozawa T, Asakage T, Onitsuka T, Fujimoto Y, Matsuura K, Kawabata K, Hayashi R
Jpn J Clin Oncol 2019 May 1;49(5):452-457. doi: 10.1093/jjco/hyz019. PMID: 30811540
Postcricoid carcinoma: is organ preservation justified in T3?
Kadapa N, Mangale K, Watve P, Rao S LM, Raju AK, Subramanyeshwar Rao T
Laryngoscope 2015 Feb;125(2):356-9. Epub 2014 Jul 23 doi: 10.1002/lary.24846. PMID: 25052147
Retropharyngeal lymph node metastases in head and neck malignancies.
Coskun HH, Ferlito A, Medina JE, Robbins KT, Rodrigo JP, Strojan P, Suárez C, Takes RP, Woolgar JA, Shaha AR, de Bree R, Rinaldo A, Silver CE
Head Neck 2011 Oct;33(10):1520-9. Epub 2010 Aug 24 doi: 10.1002/hed.21526. PMID: 20737485
Cervical node metastases in laryngeal and hypopharyngeal cancer: a prospective analysis of prevalence and distribution.
Buckley JG, MacLennan K
Head Neck 2000 Jul;22(4):380-5. doi: 10.1002/1097-0347(200007)22:4<380::aid-hed11>3.0.co;2-e. PMID: 10862022

Diagnosis

Postcricoid haemangioma with laryngomalacia in infancy.
Khamalrudin N, Goh BS
BMJ Case Rep 2021 Apr 19;14(4) doi: 10.1136/bcr-2020-235936. PMID: 33875496Free PMC Article
Transoral endoscopic examination of head and neck region.
Hamada K, Ishihara R, Yamasaki Y, Akasaka T, Arao M, Iwatsubo T, Shichijo S, Matsuura N, Nakahira H, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Kawahara Y, Okada H
Dig Endosc 2018 Jul;30(4):516-521. Epub 2018 Apr 26 doi: 10.1111/den.13071. PMID: 29637617
Unique presentation of adenoid cystic carcinoma in postcricoid region: a case report and review of the literature.
Saraydaroglu O, Coskun H, Kasap M
Head Neck Pathol 2011 Dec;5(4):413-5. Epub 2011 May 11 doi: 10.1007/s12105-011-0266-y. PMID: 21559806Free PMC Article
Retropharyngeal lymph node metastases in head and neck malignancies.
Coskun HH, Ferlito A, Medina JE, Robbins KT, Rodrigo JP, Strojan P, Suárez C, Takes RP, Woolgar JA, Shaha AR, de Bree R, Rinaldo A, Silver CE
Head Neck 2011 Oct;33(10):1520-9. Epub 2010 Aug 24 doi: 10.1002/hed.21526. PMID: 20737485
Postcricoid region and cervical esophagus: normal appearance at CT and MR imaging.
Schmalfuss IM, Mancuso AA, Tart RP
Radiology 2000 Jan;214(1):237-46. doi: 10.1148/radiology.214.1.r00dc42237. PMID: 10644131

Therapy

Three strategies for displaying the postcricoid space and pyriform sinus: A matched case-controlled study of 50 patients.
Zhu G, Peng O, Li S, Zhu G, Wang S, Liu J, Yin D, Peng X, Yang T, Tang Q, Yang X
Clin Otolaryngol 2019 Mar;44(2):187-190. Epub 2018 Dec 18 doi: 10.1111/coa.13256. PMID: 30411859
Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapy.
Huang SH, Perez-Ordonez B, Liu FF, Waldron J, Ringash J, Irish J, Cummings B, Siu LL, Kim J, Weinreb I, Hope A, Gullane P, Brown D, Shi W, O'Sullivan B
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):276-83. Epub 2010 Oct 13 doi: 10.1016/j.ijrobp.2010.08.031. PMID: 20950953
Mortality and morbidity of primary pharyngogastric anastomosis following circumferential excision for hypopharyngeal malignancies.
Mehta SA, Sarkar S, Mehta AR, Mehta MS
J Surg Oncol 1990 Jan;43(1):24-7. doi: 10.1002/jso.2930430107. PMID: 2296191
Tongue flap repair of postlaryngectomy hypopharyngeal stenosis.
Calcaterra TC
Laryngoscope 1986 Jun;96(6):617-20. doi: 10.1288/00005537-198606000-00005. PMID: 3713404
Postcricoid carcinoma: a retrospective study of 13 patients.
Grant HR, Clifford P
Eur J Surg Oncol 1985 Mar;11(1):37-40. PMID: 2580741

Prognosis

Individualized elective irradiation of the clinically node-negative neck in definitive radiotherapy for head and neck squamous cell carcinoma.
Kou J, Lin L, Jiao CY, Tian MQ, Zhou GQ, Jiang X, Ma J, Qi ZY, Lu Y, Sun Y
Cancer Commun (Lond) 2021 Apr;41(4):303-315. Epub 2021 Feb 26 doi: 10.1002/cac2.12145. PMID: 33636050Free PMC Article
Pharyngeal observation via transoral endoscopy using a lip cover-type mouthpiece.
Iwatsubo T, Ishihara R, Nakagawa K, Ohmori M, Iwagami H, Matsuno K, Inoue S, Nakahira H, Matsuura N, Shichijo S, Maekawa A, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Higuchi K
J Gastroenterol Hepatol 2019 Aug;34(8):1384-1389. Epub 2019 Jan 21 doi: 10.1111/jgh.14574. PMID: 30561830
Clinicopathological factors influencing the outcomes of surgical treatment in patients with T4a hypopharyngeal cancer.
Kim SY, Rho YS, Choi EC, Kim MS, Woo JH, Lee DH, Chung EJ, Park MW, Kim DH, Joo YH
BMC Cancer 2017 Dec 29;17(1):904. doi: 10.1186/s12885-017-3880-6. PMID: 29284434Free PMC Article
Postcricoid carcinoma: is organ preservation justified in T3?
Kadapa N, Mangale K, Watve P, Rao S LM, Raju AK, Subramanyeshwar Rao T
Laryngoscope 2015 Feb;125(2):356-9. Epub 2014 Jul 23 doi: 10.1002/lary.24846. PMID: 25052147
Retropharyngeal lymph node metastases in head and neck malignancies.
Coskun HH, Ferlito A, Medina JE, Robbins KT, Rodrigo JP, Strojan P, Suárez C, Takes RP, Woolgar JA, Shaha AR, de Bree R, Rinaldo A, Silver CE
Head Neck 2011 Oct;33(10):1520-9. Epub 2010 Aug 24 doi: 10.1002/hed.21526. PMID: 20737485

Clinical prediction guides

Postcricoid haemangioma with laryngomalacia in infancy.
Khamalrudin N, Goh BS
BMJ Case Rep 2021 Apr 19;14(4) doi: 10.1136/bcr-2020-235936. PMID: 33875496Free PMC Article
Surgical management around the paratracheal area of hypopharyngeal cancer.
Tomioka T, Beppu T, Fujii T, Ozawa T, Asakage T, Onitsuka T, Fujimoto Y, Matsuura K, Kawabata K, Hayashi R
Jpn J Clin Oncol 2019 May 1;49(5):452-457. doi: 10.1093/jjco/hyz019. PMID: 30811540
Pharyngeal observation via transoral endoscopy using a lip cover-type mouthpiece.
Iwatsubo T, Ishihara R, Nakagawa K, Ohmori M, Iwagami H, Matsuno K, Inoue S, Nakahira H, Matsuura N, Shichijo S, Maekawa A, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Higuchi K
J Gastroenterol Hepatol 2019 Aug;34(8):1384-1389. Epub 2019 Jan 21 doi: 10.1111/jgh.14574. PMID: 30561830
Transoral endoscopic examination of head and neck region.
Hamada K, Ishihara R, Yamasaki Y, Akasaka T, Arao M, Iwatsubo T, Shichijo S, Matsuura N, Nakahira H, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Kawahara Y, Okada H
Dig Endosc 2018 Jul;30(4):516-521. Epub 2018 Apr 26 doi: 10.1111/den.13071. PMID: 29637617
Postcricoid carcinoma: is organ preservation justified in T3?
Kadapa N, Mangale K, Watve P, Rao S LM, Raju AK, Subramanyeshwar Rao T
Laryngoscope 2015 Feb;125(2):356-9. Epub 2014 Jul 23 doi: 10.1002/lary.24846. PMID: 25052147

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