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Odontogenic cyst

MedGen UID:
14461
•Concept ID:
C0028879
•
Disease or Syndrome
Synonyms: Cyst, Odontogenic; Cysts, Odontogenic; Odontogenic Cyst; Odontogenic Cysts
SNOMED CT: Odontogenic cyst (235110008); Odontogenic cyst (28727003); Developmental odontogenic cyst (28727003)
 
Monarch Initiative: MONDO:0006328

Definition

A cyst in the jaw that arises from tissues of tooth development. [from NCI]

Professional guidelines

PubMed

Assessment of Hounsfield unit in the differential diagnosis of odontogenic cysts.
Uehara K, Hisatomi M, Munhoz L, Kawazu T, Yanagi Y, Okada S, Takeshita Y, Saito EA, Asaumi J
Dentomaxillofac Radiol 2021 Feb 1;50(2):20200188. Epub 2020 Aug 12 doi: 10.1259/dmfr.20200188. PMID: 32783633Free PMC Article
Benign and Malignant Oral Lesions in Children and Adolescents: An Organized Approach to Diagnosis and Management.
Yuhan BT, Svider PF, Mutchnick S, Sheyn A
Pediatr Clin North Am 2018 Oct;65(5):1033-1050. doi: 10.1016/j.pcl.2018.05.013. PMID: 30213347
Odontogenic keratocysts/keratocystic odontogenic tumours: biological characteristics, clinical manifestation and treatment.
Pazdera J, Kolar Z, Zboril V, Tvrdy P, Pink R
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014 Jun;158(2):170-4. Epub 2012 Jun 1 doi: 10.5507/bp.2012.048. PMID: 23073530

Recent clinical studies

Etiology

Comparative analysis between developmental and inflammatory odontogenic cysts: retrospective study and literature review.
Kammer PV, Mello FW, Rivero ERC
Oral Maxillofac Surg 2020 Mar;24(1):73-84. Epub 2019 Dec 19 doi: 10.1007/s10006-019-00816-8. PMID: 31858303
Odontogenic Cysts.
Rajendra Santosh AB
Dent Clin North Am 2020 Jan;64(1):105-119. Epub 2019 Oct 18 doi: 10.1016/j.cden.2019.08.002. PMID: 31735221
Intraosseous mucoepidermoid carcinoma: Outcome review.
Merna C, Kita A, Wester J, Diaz-Aguilar D, Goldstein JD, Palma Diaz F, Blackwell K, St John MA
Laryngoscope 2018 May;128(5):1083-1092. Epub 2017 Aug 22 doi: 10.1002/lary.26832. PMID: 28833169
Calcifying epithelial odontogenic cyst.
Manohar B, Baidya D, Shetty N, Mathur A, Makhijani B
J Exp Ther Oncol 2017 Nov;12(2):151-156. PMID: 29161784
Ameloblastomatous Gorlin's cyst.
Kamboj M, Juneja M
J Oral Sci 2007 Dec;49(4):319-23. doi: 10.2334/josnusd.49.319. PMID: 18195516

Diagnosis

Unicystic Ameloblastoma of Mandible: A Case Report.
Rayamajhi S, Shrestha S, Shakya S, Bhandari S, Twayana AR, Shahi K
JNMA J Nepal Med Assoc 2022 Jul 1;60(251):657-660. doi: 10.31729/jnma.7566. PMID: 36705195Free PMC Article
Odontogenic and Developmental Oral Lesions in Pediatric Patients.
Bilodeau EA, Hunter KD
Head Neck Pathol 2021 Mar;15(1):71-84. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01284-3. PMID: 33723756Free PMC Article
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Benign Jaw Lesions.
Gohel A, Villa A, Sakai O
Dent Clin North Am 2016 Jan;60(1):125-41. doi: 10.1016/j.cden.2015.08.005. PMID: 26614952
Ameloblastic Carcinoma.
Gunaratne DA, Coleman HG, Lim L, Morgan GJ
Am J Case Rep 2015 Jul 1;16:415-9. doi: 10.12659/AJCR.893918. PMID: 26126621Free PMC Article

Therapy

5-fluorouacil in the treatment of odontogenic keratocysts-incidence of recurrence and inferior alveolar nerve paresthesia: a systematic review.
Melean LP, Guerrero LM, Lopez L
Oral Maxillofac Surg 2023 Sep;27(3):489-496. Epub 2022 Jun 18 doi: 10.1007/s10006-022-01090-x. PMID: 35715708
A comparative study of the expression of cyclin D1, COX-2, and KI-67 in odontogenic keratocyst vs. ameloblastoma vs. orthokeratinized odontogenic cyst.
Martín-Hernán F, Campo-Trapero J, Cano-Sánchez J, García-Martín R, Martínez-López M, Ballestín-Carcavilla C
Rev Esp Patol 2022 Apr-Jun;55(2):90-95. Epub 2021 Aug 28 doi: 10.1016/j.patol.2021.05.005. PMID: 35483774
Comparing the efficacy of sinus irrigation with traditional Caldwell-Luc procedure following odontogenic cyst surgery involving the maxillary sinus.
Gang N, JiaMin C, Ye W, FuPing X, HuanHuan L, LiSong L
Sci Rep 2021 Sep 13;11(1):18136. doi: 10.1038/s41598-021-97477-z. PMID: 34518580Free PMC Article
Reclassification and treatment of odontogenic keratocysts: A cohort study.
Ribeiro-Júnior O, Borba AM, Alves CAF, Gouveia MM, Deboni MCZ, Naclério-Homem MDG
Braz Oral Res 2017 Dec 18;31:e98. doi: 10.1590/1807-3107bor-2017.vol31.0098. PMID: 29267660
Case series and review of glandular odontogenic cyst with emphasis on treatment modalities.
Momeni Roochi M, Tavakoli I, Ghazi FM, Tavakoli A
J Craniomaxillofac Surg 2015 Jul;43(6):746-50. Epub 2015 Apr 11 doi: 10.1016/j.jcms.2015.03.030. PMID: 25971944

Prognosis

Ghost cells unveiled: A comprehensive review.
Garg A, Malhotra R, Urs AB
J Oral Biosci 2022 Jun;64(2):202-209. Epub 2022 Apr 6 doi: 10.1016/j.job.2022.03.005. PMID: 35398253
Odontogenic and Developmental Oral Lesions in Pediatric Patients.
Bilodeau EA, Hunter KD
Head Neck Pathol 2021 Mar;15(1):71-84. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01284-3. PMID: 33723756Free PMC Article
Intraosseous mucoepidermoid carcinoma: Outcome review.
Merna C, Kita A, Wester J, Diaz-Aguilar D, Goldstein JD, Palma Diaz F, Blackwell K, St John MA
Laryngoscope 2018 May;128(5):1083-1092. Epub 2017 Aug 22 doi: 10.1002/lary.26832. PMID: 28833169
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Developmental odontogenic cysts. An update.
Shear M
J Oral Pathol Med 1994 Jan;23(1):1-11. doi: 10.1111/j.1600-0714.1994.tb00246.x. PMID: 8138974

Clinical prediction guides

Buccal bifurcation cyst: A case series and review of the literature.
Ruddocks LA, Fitzpatrick SG, Bhattacharyya I, Islam MN, Cohen DM
J Am Dent Assoc 2022 May;153(5):421-428. Epub 2022 Feb 4 doi: 10.1016/j.adaj.2021.10.002. PMID: 35125168
Benign and Malignant Oral Lesions in Children and Adolescents: An Organized Approach to Diagnosis and Management.
Yuhan BT, Svider PF, Mutchnick S, Sheyn A
Pediatr Clin North Am 2018 Oct;65(5):1033-1050. doi: 10.1016/j.pcl.2018.05.013. PMID: 30213347
Intraosseous mucoepidermoid carcinoma: Outcome review.
Merna C, Kita A, Wester J, Diaz-Aguilar D, Goldstein JD, Palma Diaz F, Blackwell K, St John MA
Laryngoscope 2018 May;128(5):1083-1092. Epub 2017 Aug 22 doi: 10.1002/lary.26832. PMID: 28833169
Glandular odontogenic cyst: An updated analysis of 169 cases reported in the literature.
Chrcanovic BR, Gomez RS
Oral Dis 2018 Jul;24(5):717-724. Epub 2017 Aug 18 doi: 10.1111/odi.12719. PMID: 28744957
Calcifying odontogenic cysts.
Rojo R, Prados-Frutos JC, Gutierrez Lázaro I, Herguedas Alonso JA
J Stomatol Oral Maxillofac Surg 2017 Apr;118(2):122-124. Epub 2017 Feb 11 doi: 10.1016/j.jormas.2016.10.007. PMID: 28345512

Recent systematic reviews

Cyst or Tumor? A systematic review and meta-analysis on the expression of p53 marker in Odontogenic Keratocysts.
Slusarenko da Silva Y, Stoelinga PJW, Grillo R, da Graça Naclério-Homem M
J Craniomaxillofac Surg 2021 Dec;49(12):1101-1106. Epub 2021 Sep 28 doi: 10.1016/j.jcms.2021.09.015. PMID: 34620539
Gingival cyst of the adult, lateral periodontal cyst, and botryoid odontogenic cyst: An updated systematic review.
Chrcanovic BR, Gomez RS
Oral Dis 2019 Jan;25(1):26-33. Epub 2018 Feb 8 doi: 10.1111/odi.12808. PMID: 29156092
Frequency of odontogenic cysts and tumors: a systematic review.
Johnson NR, Gannon OM, Savage NW, Batstone MD
J Investig Clin Dent 2014 Feb;5(1):9-14. Epub 2013 Jun 14 doi: 10.1111/jicd.12044. PMID: 23766099
Orthokeratinized odontogenic cyst: a systematic review.
Macdonald-Jankowski DS
Dentomaxillofac Radiol 2010 Dec;39(8):455-67. doi: 10.1259/dmfr/19728573. PMID: 21062939Free PMC Article
Glandular odontogenic cyst: systematic review.
Macdonald-Jankowski DS
Dentomaxillofac Radiol 2010 Mar;39(3):127-39. doi: 10.1259/dmfr/30943934. PMID: 20203274Free PMC Article

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