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Brainstem neoplasm

MedGen UID:
146207
•Concept ID:
C0677866
•
Neoplastic Process
Synonyms: Brain Stem Neoplasm; Brain Stem Neoplasms; Brain Stem Tumor; Brain Stem Tumors; Brainstem Neoplasm; Brainstem Neoplasms; Brainstem Tumor; Brainstem Tumors; Neoplasm, Brain Stem; Neoplasm, Brainstem; Neoplasms, Brain Stem; Neoplasms, Brainstem; Tumor, Brain Stem
SNOMED CT: Neoplasm of brain stem (126961004)
 
Monarch Initiative: MONDO:0021228

Definition

A benign or malignant neoplasm that affects the brain stem. [from NCI]

Professional guidelines

PubMed

Primary central nervous system lymphoma.
Ferreri AJM, Calimeri T, Cwynarski K, Dietrich J, Grommes C, Hoang-Xuan K, Hu LS, Illerhaus G, Nayak L, Ponzoni M, Batchelor TT
Nat Rev Dis Primers 2023 Jun 15;9(1):29. doi: 10.1038/s41572-023-00439-0. PMID: 37322012Free PMC Article
Dissecting the treatment-naive ecosystem of human melanoma brain metastasis.
Biermann J, Melms JC, Amin AD, Wang Y, Caprio LA, Karz A, Tagore S, Barrera I, Ibarra-Arellano MA, Andreatta M, Fullerton BT, Gretarsson KH, Sahu V, Mangipudy VS, Nguyen TTT, Nair A, Rogava M, Ho P, Koch PD, Banu M, Humala N, Mahajan A, Walsh ZH, Shah SB, Vaccaro DH, Caldwell B, Mu M, Wünnemann F, Chazotte M, Berhe S, Luoma AM, Driver J, Ingham M, Khan SA, Rapisuwon S, Slingluff CL Jr, Eigentler T, Röcken M, Carvajal R, Atkins MB, Davies MA, Agustinus A, Bakhoum SF, Azizi E, Siegelin M, Lu C, Carmona SJ, Hibshoosh H, Ribas A, Canoll P, Bruce JN, Bi WL, Agrawal P, Schapiro D, Hernando E, Macosko EZ, Chen F, Schwartz GK, Izar B
Cell 2022 Jul 7;185(14):2591-2608.e30. doi: 10.1016/j.cell.2022.06.007. PMID: 35803246Free PMC Article
Cancer Stem Cells: Significance in Origin, Pathogenesis and Treatment of Glioblastoma.
Biserova K, Jakovlevs A, Uljanovs R, Strumfa I
Cells 2021 Mar 11;10(3) doi: 10.3390/cells10030621. PMID: 33799798Free PMC Article

Recent clinical studies

Diagnosis

Intraparenchymal papillary meningioma of brainstem: case report and literature review.
Jiang XB, Ke C, Han ZA, Lin SH, Mou YG, Luo RZ, Wu SX, Chen ZP
World J Surg Oncol 2012 Jan 12;10:10. doi: 10.1186/1477-7819-10-10. PMID: 22236763Free PMC Article
Lyme disease of the brainstem.
Kalina P, Decker A, Kornel E, Halperin JJ
Neuroradiology 2005 Dec;47(12):903-7. Epub 2005 Sep 13 doi: 10.1007/s00234-005-1440-2. PMID: 16158278
Intracranial dural arteriovenous fistula mimicking brainstem neoplasm.
Crum BA, Link M
Neurology 2004 Jun 22;62(12):2330-1. doi: 10.1212/01.wnl.0000130342.68494.78. PMID: 15210912
Histiocytic lesion mimicking intrinsic brainstem neoplasm. Case report.
Weaver KD, Armao D, Wiley JM, Ewend MG
J Neurosurg 1999 Dec;91(6):1037-40. doi: 10.3171/jns.1999.91.6.1037. PMID: 10584853
MRI demonstration of midbrain deformity in association with Chiari malformation.
Hunter JV, Youl BD, Moseley IF
Neuroradiology 1992;34(5):399-401. doi: 10.1007/BF00596499. PMID: 1407519

Therapy

Embryonal tumor with abundant neuropil and true rosettes (ETANTR): a new distinctive variety of pediatric PNET: a case-based update.
Ferri Niguez B, Martínez-Lage JF, Almagro MJ, Fuster JL, Serrano C, Torroba MA, Sola J
Childs Nerv Syst 2010 Aug;26(8):1003-8. Epub 2010 May 25 doi: 10.1007/s00381-010-1179-x. PMID: 20499240
Primary angiitis of the central nervous system mimicking dissemination from brainstem neoplasm: a case report.
Nabika S, Kiya K, Satoh H, Mizoue T, Araki H, Oshita J, Nishisaka T, Kurisu K, Sugiyama K
Surg Neurol 2008 Aug;70(2):182-5; discussion 185. Epub 2008 Feb 8 doi: 10.1016/j.surneu.2007.05.008. PMID: 18261774
Steroid responsive fluctuating sensorineural hearing loss due to juvenile pilocytic astrocytoma involving the cerebellopontine angle.
Mallur PS, Wisoff JH, Lalwani AK
Int J Pediatr Otorhinolaryngol 2008 Apr;72(4):529-34. Epub 2008 Feb 5 doi: 10.1016/j.ijporl.2007.12.010. PMID: 18255162

Prognosis

Embryonal tumor with abundant neuropil and true rosettes (ETANTR): a new distinctive variety of pediatric PNET: a case-based update.
Ferri Niguez B, Martínez-Lage JF, Almagro MJ, Fuster JL, Serrano C, Torroba MA, Sola J
Childs Nerv Syst 2010 Aug;26(8):1003-8. Epub 2010 May 25 doi: 10.1007/s00381-010-1179-x. PMID: 20499240
Primary angiitis of the central nervous system mimicking dissemination from brainstem neoplasm: a case report.
Nabika S, Kiya K, Satoh H, Mizoue T, Araki H, Oshita J, Nishisaka T, Kurisu K, Sugiyama K
Surg Neurol 2008 Aug;70(2):182-5; discussion 185. Epub 2008 Feb 8 doi: 10.1016/j.surneu.2007.05.008. PMID: 18261774

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