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Peroneal neuropathy

MedGen UID:
148182
•Concept ID:
C0747533
•
Disease or Syndrome
Synonyms: Fibular Nerve Disease; Fibular Nerve Diseases; Mononeuropathy, Peroneal; Nerve Disease, Fibular; Neuropathy, Peroneal; Peroneal Mononeuropathies; Peroneal Mononeuropathy; Peroneal Nerve Disease; Peroneal Nerve Diseases; Peroneal Neuropathies; Peroneal Neuropathy
 
Monarch Initiative: MONDO:0002910

Definition

Disease involving the common peroneal nerve or its branches, the deep and superficial peroneal nerves. Lesions of the deep peroneal nerve are associated with paralysis of dorsiflexion of the ankle and toes and loss of sensation from the web space between the first and second toe. Lesions of the superficial peroneal nerve result in weakness or paralysis of the peroneal muscles (which evert the foot) and loss of sensation over the dorsal and lateral surface of the leg. Traumatic injury to the common peroneal nerve near the head of the fibula is a relatively common cause of this condition. (From Joynt, Clinical Neurology, 1995, Ch51, p31) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeroneal neuropathy

Professional guidelines

PubMed

The lower extremity nerve injuries - own experience in surgical treatment.
Gosk J, Rutowski R, Rabczyński J
Folia Neuropathol 2005;43(3):148-52. PMID: 16245209
Practice parameter: utility of electrodiagnostic techniques in evaluating patients with suspected peroneal neuropathy: an evidence-based review.
Marciniak C, Armon C, Wilson J, Miller R
Muscle Nerve 2005 Apr;31(4):520-7. doi: 10.1002/mus.20308. PMID: 15768387
Diagnosis and management of common compression and entrapment neuropathies.
Campbell WW
Neurol Clin 1997 Aug;15(3):549-67. doi: 10.1016/s0733-8619(05)70333-9. PMID: 9227952

Recent clinical studies

Etiology

Peroneal nerve decompression.
Corriveau M, Lescher JD, Hanna AS
Neurosurg Focus 2018 Jan;44(VideoSuppl1):V6. doi: 10.3171/2018.1.FocusVid.17575. PMID: 29291292
Electrophysiologic features of fibular neuropathy in childhood and adolescence.
Karakis I, Khoshnoodi M, Liew W, Nguyen ES, Jones HR, Darras BT, Kang PB
Muscle Nerve 2017 May;55(5):693-697. Epub 2017 Jan 24 doi: 10.1002/mus.25403. PMID: 27615598
Common peroneal neuropathy and cancer.
Simon NG, Kiernan MC
Intern Med J 2012 Jul;42(7):837-40. doi: 10.1111/j.1445-5994.2012.02836.x. PMID: 22805690
Common peroneal nerve decompression.
Ramanan M, Chandran KN
ANZ J Surg 2011 Oct;81(10):707-12. doi: 10.1111/j.1445-2197.2010.05607.x. PMID: 22295311
Controversial entrapment neuropathies.
Campbell WW, Landau ME
Neurosurg Clin N Am 2008 Oct;19(4):597-608, vi-vii. doi: 10.1016/j.nec.2008.07.001. PMID: 19010284

Diagnosis

Fibular (peroneal) neuropathy.
Benstead TJ
Handb Clin Neurol 2024;201:149-164. doi: 10.1016/B978-0-323-90108-6.00008-9. PMID: 38697737
Acute Peroneal Neuropathy and Foot Drop in Two Adolescent Female Athletes with New-Onset Diabetes.
Jaeger JA, Gohil A, Nebesio TD
Curr Sports Med Rep 2022 Feb 1;21(2):39-41. doi: 10.1249/JSR.0000000000000931. PMID: 35120048
Lower extremity entrapment neuropathies.
Madani S, Doughty C
Best Pract Res Clin Rheumatol 2020 Jun;34(3):101565. Epub 2020 Jul 31 doi: 10.1016/j.berh.2020.101565. PMID: 32747188
Entrapment Neuropathies of the Lower Extremity.
Bowley MP, Doughty CT
Med Clin North Am 2019 Mar;103(2):371-382. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.013. PMID: 30704688
Peroneal neuropathy.
Katirji B
Neurol Clin 1999 Aug;17(3):567-91, vii. doi: 10.1016/s0733-8619(05)70153-5. PMID: 10393754

Therapy

Peroneal neuropathy and bariatric surgery: untying the knot.
Fares MY, Dimassi Z, Fares J, Musharrafieh U
Int J Neurosci 2020 Apr;130(4):417-423. Epub 2020 Jan 6 doi: 10.1080/00207454.2019.1694926. PMID: 31735096
Neuroma of medial dorsal cutaneous nerve of superficial peroneal nerve after ankle arthroscopy.
Shim JS, Lee JH, Han SH, Kim M, Lee HJ, Min K
PM R 2014 Sep;6(9):849-52. Epub 2014 Jan 29 doi: 10.1016/j.pmrj.2014.01.018. PMID: 24486918
Atypical presentations of common peroneal neuropathy.
Annaswamy TM, Li HY
PM R 2012 Jun;4(6):462-5. doi: 10.1016/j.pmrj.2012.03.019. PMID: 22732160
Development of lepromatous leprosy following etanercept treatment for arthritis.
Lydakis C, Ioannidou D, Koumpa I, Giannikaki E, Thalassinos E, Krasoudaki E, Miyakis S
Clin Rheumatol 2012 Feb;31(2):395-8. Epub 2011 Dec 15 doi: 10.1007/s10067-011-1903-2. PMID: 22170033
Acute common peroneal neuropathy due to hand positioning in normal labor and delivery.
Radawski MM, Strakowski JA, Johnson EW
Obstet Gynecol 2011 Aug;118(2 Pt 2):421-423. doi: 10.1097/AOG.0b013e31821dac98. PMID: 21768840

Prognosis

Electrodiagnostic Assessment of Uncommon Mononeuropathies.
Hayat G, Calvin JS
Neurol Clin 2021 Nov;39(4):957-981. Epub 2021 Sep 3 doi: 10.1016/j.ncl.2021.06.005. PMID: 34602221
Common peroneal nerve decompression.
Ramanan M, Chandran KN
ANZ J Surg 2011 Oct;81(10):707-12. doi: 10.1111/j.1445-2197.2010.05607.x. PMID: 22295311
Foot drop: where, why and what to do?
Stewart JD
Pract Neurol 2008 Jun;8(3):158-69. doi: 10.1136/jnnp.2008.149393. PMID: 18502948
Sciatic neuropathy.
Yuen EC, So YT
Neurol Clin 1999 Aug;17(3):617-31, viii. doi: 10.1016/s0733-8619(05)70155-9. PMID: 10393756
Peroneal neuropathy.
Katirji B
Neurol Clin 1999 Aug;17(3):567-91, vii. doi: 10.1016/s0733-8619(05)70153-5. PMID: 10393754

Clinical prediction guides

Analysis of outcome reporting in common peroneal neuropathy studies: a systematic review of the literature.
Muhlestein WE, Wilson TJ
Acta Neurochir (Wien) 2023 Sep;165(9):2597-2604. Epub 2023 Aug 16 doi: 10.1007/s00701-023-05744-x. PMID: 37587319
Foot drop: where, why and what to do?
Stewart JD
Pract Neurol 2008 Jun;8(3):158-69. doi: 10.1136/jnnp.2008.149393. PMID: 18502948
Peroneal neuropathy following successful bariatric surgery. Case report and review of the literature.
Elias WJ, Pouratian N, Oskouian RJ, Schirmer B, Burns T
J Neurosurg 2006 Oct;105(4):631-5. doi: 10.3171/jns.2006.105.4.631. PMID: 17044570
A case of peroneal neuropathy-induced footdrop. Correlated and compensatory lower-extremity function.
Vlahovic TC, Ribeiro CE, Lamm BM, Denmark JA, Walters RG, Talbert T, Penugonda S, Furmato JA, Brower DJ, McMahon J, Bhimji S, Hillstrom HJ
J Am Podiatr Med Assoc 2000 Sep;90(8):411-20. doi: 10.7547/87507315-90-8-411. PMID: 11021053
Slimmer's paralysis--peroneal neuropathy during weight reduction.
Sotaniemi KA
J Neurol Neurosurg Psychiatry 1984 May;47(5):564-6. doi: 10.1136/jnnp.47.5.564. PMID: 6610724Free PMC Article

Recent systematic reviews

Analysis of outcome reporting in common peroneal neuropathy studies: a systematic review of the literature.
Muhlestein WE, Wilson TJ
Acta Neurochir (Wien) 2023 Sep;165(9):2597-2604. Epub 2023 Aug 16 doi: 10.1007/s00701-023-05744-x. PMID: 37587319
Editorial. Analysis of outcome reporting in common peroneal neuropathy studies: a systematic review of the literature.
Barone DG, Spinner RJ
Acta Neurochir (Wien) 2023 Sep;165(9):2605-2606. Epub 2023 Aug 12 doi: 10.1007/s00701-023-05747-8. PMID: 37568005
Management and outcomes of proximal tibiofibular joint ganglion cysts: A systematic review.
Huntington LS, Talia A, Devitt BM, Batty L
Knee 2022 Aug;37:60-70. Epub 2022 Jun 10 doi: 10.1016/j.knee.2022.05.009. PMID: 35696835
Nervous system dysfunction in Henoch-Schonlein syndrome: systematic review of the literature.
Garzoni L, Vanoni F, Rizzi M, Simonetti GD, Goeggel Simonetti B, Ramelli GP, Bianchetti MG
Rheumatology (Oxford) 2009 Dec;48(12):1524-9. Epub 2009 Sep 21 doi: 10.1093/rheumatology/kep282. PMID: 19797041

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