U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Radial neuropathy

MedGen UID:
148185
•Concept ID:
C0748226
•
Disease or Syndrome
Synonyms: Mononeuropathy, Radial; Neuropathy, Radial; Radial Mononeuropathies; Radial Mononeuropathy; Radial Nerve Disease; Radial Nerve Diseases; Radial Neuropathies; Radial Neuropathy; Supinator Syndrome; Supinator Syndromes; Syndrome, Supinator
SNOMED CT: Radial neuropathy (16644004)
 
Monarch Initiative: MONDO:0001459

Definition

Disease involving the radial nerve. Clinical features include weakness of elbow extension, elbow flexion, supination of the forearm, wrist and finger extension, and thumb abduction. Sensation may be impaired over regions of the dorsal forearm. Common sites of compression or traumatic injury include the axilla and radial groove of the humerus. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRadial neuropathy

Professional guidelines

PubMed

Incidence of common compressive neuropathies in primary care.
Latinovic R, Gulliford MC, Hughes RA
J Neurol Neurosurg Psychiatry 2006 Feb;77(2):263-5. doi: 10.1136/jnnp.2005.066696. PMID: 16421136Free PMC Article
Management of large high-flow arteriovenous malformations of the shoulder and upper extremity with transcatheter embolotherapy.
Dickey KW, Pollak JS, Meier GH 3rd, Denny DF, White RI Jr
J Vasc Interv Radiol 1995 Sep-Oct;6(5):765-73. doi: 10.1016/s1051-0443(95)71183-6. PMID: 8541682

Recent clinical studies

Etiology

Humeral shaft fracture: systematic review of non-operative and operative treatment.
Van Bergen SH, Mahabier KC, Van Lieshout EMM, Van der Torre T, Notenboom CAW, Jawahier PA, Verhofstad MHJ, Den Hartog D
Arch Orthop Trauma Surg 2023 Aug;143(8):5035-5054. Epub 2023 Apr 24 doi: 10.1007/s00402-023-04836-8. PMID: 37093269Free PMC Article
Radial nerve injuries.
Ljungquist KL, Martineau P, Allan C
J Hand Surg Am 2015 Jan;40(1):166-72. Epub 2014 Dec 1 doi: 10.1016/j.jhsa.2014.05.010. PMID: 25442768
Radial tunnel syndrome.
Naam NH, Nemani S
Orthop Clin North Am 2012 Oct;43(4):529-36. doi: 10.1016/j.ocl.2012.07.022. PMID: 23026469
Controversial entrapment neuropathies.
Campbell WW, Landau ME
Neurosurg Clin N Am 2008 Oct;19(4):597-608, vi-vii. doi: 10.1016/j.nec.2008.07.001. PMID: 19010284
Radial nerve palsy associated with fractures of the shaft of the humerus: a systematic review.
Shao YC, Harwood P, Grotz MR, Limb D, Giannoudis PV
J Bone Joint Surg Br 2005 Dec;87(12):1647-52. doi: 10.1302/0301-620X.87B12.16132. PMID: 16326879

Diagnosis

Radial neuropathy.
Chalk C
Handb Clin Neurol 2024;201:127-134. doi: 10.1016/B978-0-323-90108-6.00015-6. PMID: 38697735
Radial Tunnel Syndrome: Review and Best Evidence.
Wolf JM, Patel R, Ghosh K
J Am Acad Orthop Surg 2023 Aug 1;31(15):813-819. Epub 2023 Jun 2 doi: 10.5435/JAAOS-D-23-00314. PMID: 37276490
Entrapment Neuropathies of the Upper Extremity.
Doughty CT, Bowley MP
Med Clin North Am 2019 Mar;103(2):357-370. doi: 10.1016/j.mcna.2018.10.012. PMID: 30704687
Radial nerve injuries.
Ljungquist KL, Martineau P, Allan C
J Hand Surg Am 2015 Jan;40(1):166-72. Epub 2014 Dec 1 doi: 10.1016/j.jhsa.2014.05.010. PMID: 25442768
Radial tunnel syndrome.
Naam NH, Nemani S
Orthop Clin North Am 2012 Oct;43(4):529-36. doi: 10.1016/j.ocl.2012.07.022. PMID: 23026469

Therapy

Humeral shaft fracture: systematic review of non-operative and operative treatment.
Van Bergen SH, Mahabier KC, Van Lieshout EMM, Van der Torre T, Notenboom CAW, Jawahier PA, Verhofstad MHJ, Den Hartog D
Arch Orthop Trauma Surg 2023 Aug;143(8):5035-5054. Epub 2023 Apr 24 doi: 10.1007/s00402-023-04836-8. PMID: 37093269Free PMC Article
Radial Nerve Palsy After Humeral Shaft Fractures: The Case for Early Exploration and a New Classification to Guide Treatment and Prognosis.
Chang G, Ilyas AM
Hand Clin 2018 Feb;34(1):105-112. doi: 10.1016/j.hcl.2017.09.011. PMID: 29169591
Radial tunnel syndrome.
Naam NH, Nemani S
Orthop Clin North Am 2012 Oct;43(4):529-36. doi: 10.1016/j.ocl.2012.07.022. PMID: 23026469
Complications of total elbow arthroplasty.
Kim JM, Mudgal CS, Konopka JF, Jupiter JB
J Am Acad Orthop Surg 2011 Jun;19(6):328-39. doi: 10.5435/00124635-201106000-00003. PMID: 21628644
What's new in common upper extremity entrapment neuropathies.
Toussaint CP, Zager EL
Neurosurg Clin N Am 2008 Oct;19(4):573-81, vi. doi: 10.1016/j.nec.2008.07.031. PMID: 19010282

Prognosis

Radial neuropathy.
Chalk C
Handb Clin Neurol 2024;201:127-134. doi: 10.1016/B978-0-323-90108-6.00015-6. PMID: 38697735
Radial nerve compression: anatomical perspective and clinical consequences.
Węgiel A, Karauda P, Zielinska N, Tubbs RS, Olewnik Ł
Neurosurg Rev 2023 Feb 13;46(1):53. doi: 10.1007/s10143-023-01944-2. PMID: 36781706Free PMC Article
Radial nerve injuries.
Ljungquist KL, Martineau P, Allan C
J Hand Surg Am 2015 Jan;40(1):166-72. Epub 2014 Dec 1 doi: 10.1016/j.jhsa.2014.05.010. PMID: 25442768
Radial nerve palsy associated with fractures of the shaft of the humerus: a systematic review.
Shao YC, Harwood P, Grotz MR, Limb D, Giannoudis PV
J Bone Joint Surg Br 2005 Dec;87(12):1647-52. doi: 10.1302/0301-620X.87B12.16132. PMID: 16326879
Radial neuropathy.
Carlson N, Logigian EL
Neurol Clin 1999 Aug;17(3):499-523, vi. doi: 10.1016/s0733-8619(05)70150-x. PMID: 10393751

Clinical prediction guides

Humeral shaft fracture: systematic review of non-operative and operative treatment.
Van Bergen SH, Mahabier KC, Van Lieshout EMM, Van der Torre T, Notenboom CAW, Jawahier PA, Verhofstad MHJ, Den Hartog D
Arch Orthop Trauma Surg 2023 Aug;143(8):5035-5054. Epub 2023 Apr 24 doi: 10.1007/s00402-023-04836-8. PMID: 37093269Free PMC Article
Minimally invasive plate osteosynthesis via posterior approach for type B and C fractures of distal humeral shaft: surgical tactics and a clinical series.
Jitprapaikulsarn S, Gromprasit A, Sukha K, Patamamongkonchai C, Jiamton C
Eur J Orthop Surg Traumatol 2023 May;33(4):1431-1437. Epub 2022 Mar 29 doi: 10.1007/s00590-022-03255-6. PMID: 35377077
Radial Nerve Palsy After Humeral Shaft Fractures: The Case for Early Exploration and a New Classification to Guide Treatment and Prognosis.
Chang G, Ilyas AM
Hand Clin 2018 Feb;34(1):105-112. doi: 10.1016/j.hcl.2017.09.011. PMID: 29169591
Humerus shaft fracture complicated by radial nerve palsy: Is surgical exploration necessary?
Rocchi M, Tarallo L, Mugnai R, Adani R
Musculoskelet Surg 2016 Dec;100(Suppl 1):53-60. Epub 2016 Nov 30 doi: 10.1007/s12306-016-0414-3. PMID: 27900704
Reliability and validity of the Medical Research Council (MRC) scale and a modified scale for testing muscle strength in patients with radial palsy.
Paternostro-Sluga T, Grim-Stieger M, Posch M, Schuhfried O, Vacariu G, Mittermaier C, Bittner C, Fialka-Moser V
J Rehabil Med 2008 Aug;40(8):665-71. doi: 10.2340/16501977-0235. PMID: 19020701

Recent systematic reviews

Radial Nerve Palsy Associated with Humeral Shaft Fractures in Children.
Łukasz W, Ryszard T, Maria D
Biomed Res Int 2023;2023:3974604. Epub 2023 Dec 1 doi: 10.1155/2023/3974604. PMID: 38075371Free PMC Article
Humeral shaft fracture: systematic review of non-operative and operative treatment.
Van Bergen SH, Mahabier KC, Van Lieshout EMM, Van der Torre T, Notenboom CAW, Jawahier PA, Verhofstad MHJ, Den Hartog D
Arch Orthop Trauma Surg 2023 Aug;143(8):5035-5054. Epub 2023 Apr 24 doi: 10.1007/s00402-023-04836-8. PMID: 37093269Free PMC Article
Atraumatic proximal radial nerve entrapment. Illustrative cases and systematic review of literature.
Laumonerie P, Dufournier B, Vari N, Manchec O, Tibbo ME, Cintas P, Mansat P, Faruch-Bifeld M
Eur J Orthop Surg Traumatol 2022 Jul;32(5):811-820. Epub 2021 Jun 18 doi: 10.1007/s00590-021-03037-6. PMID: 34143309
The arcade of Frohse: a systematic review and meta-analysis.
Benes M, Kachlik D, Kunc V, Kunc V
Surg Radiol Anat 2021 May;43(5):703-711. Epub 2021 Mar 6 doi: 10.1007/s00276-021-02718-5. PMID: 33677682
Radial nerve palsy associated with fractures of the shaft of the humerus: a systematic review.
Shao YC, Harwood P, Grotz MR, Limb D, Giannoudis PV
J Bone Joint Surg Br 2005 Dec;87(12):1647-52. doi: 10.1302/0301-620X.87B12.16132. PMID: 16326879

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...