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Hypoglossal nerve palsy

MedGen UID:
154395
•Concept ID:
C0585265
•
Disease or Syndrome
Synonyms: Hypoglossal Nerve Palsies; Hypoglossal Nerve Palsy; Palsies, Hypoglossal Nerve; Palsy, Hypoglossal Nerve
SNOMED CT: Twelfth cranial nerve palsy (307405000); Hypoglossal nerve palsy (307405000)

Definition

Partial or complete paralysis of the hypoglossal nerve. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypoglossal nerve palsy

Professional guidelines

PubMed

Surgical management of extracranial carotid artery aneurysms.
Skóra JP, Kurcz J, Korta K, Szyber P, Dorobisz TA, Dorobisz AT
Vasa 2016;45(3):223-8. doi: 10.1024/0301-1526/a000528. PMID: 27129067
Hypoglossal nerve palsy after airway management for general anesthesia: an analysis of 69 patients.
Shah AC, Barnes C, Spiekerman CF, Bollag LA
Anesth Analg 2015 Jan;120(1):105-120. doi: 10.1213/ANE.0000000000000495. PMID: 25625257Free PMC Article

Recent clinical studies

Etiology

Complaints and Complications of Microlaryngoscopic Surgery.
Okui A, Konomi U, Watanabe Y
J Voice 2020 Nov;34(6):949-955. Epub 2019 May 31 doi: 10.1016/j.jvoice.2019.05.006. PMID: 31160183
Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article
Hypoglossal nerve palsy: 245 cases.
Stino AM, Smith BE, Temkit M, Reddy SN
Muscle Nerve 2016 Dec;54(6):1050-1054. Epub 2016 Nov 1 doi: 10.1002/mus.25197. PMID: 27214783
Hypoglossal nerve palsy after airway management for general anesthesia: an analysis of 69 patients.
Shah AC, Barnes C, Spiekerman CF, Bollag LA
Anesth Analg 2015 Jan;120(1):105-120. doi: 10.1213/ANE.0000000000000495. PMID: 25625257Free PMC Article
Lemierre syndrome associated with 12th cranial nerve palsy--a case report and review.
Blessing K, Toepfner N, Kinzer S, Möllmann C, Geiger J, Serr A, Hufnagel M, Müller C, Krüger M, Ridder GJ, Berner R
Int J Pediatr Otorhinolaryngol 2013 Sep;77(9):1585-8. Epub 2013 Jul 8 doi: 10.1016/j.ijporl.2013.05.030. PMID: 23845534

Diagnosis

Hypoglossal nerve palsy in IgG4-related disease.
Kaneko T, Okita Y, Kato Y, Narazaki M, Kumanogoh A
QJM 2024 Aug 1;117(8):591-592. doi: 10.1093/qjmed/hcae056. PMID: 38539040
What can be the cause of hypoglossal nerve palsy?
Karşıdağ S, Ateş MF
Emerg Med J 2021 Apr;38(4):302-307. doi: 10.1136/emermed-2020-209520. PMID: 34449425
Right hypoglossal nerve palsy due to jugular paraganglioma.
Galeano-Valle F, Donis-Sevillano E
Aten Primaria 2019 May;51(5):320-321. Epub 2019 Jan 25 doi: 10.1016/j.aprim.2018.10.003. PMID: 30686677Free PMC Article
Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article
Hypoglossal nerve palsy.
Hui AC, Tsui IW, Chan DP
Hong Kong Med J 2009 Jun;15(3):234. PMID: 19494384

Therapy

Postoperative tongue deviation by hypoglossal nerve palsy and Tapia's syndrome after cervical laminoplasty: report of two cases.
Ishihara H, Tsuji O, Okada E, Izawa Y, Kato J, Suzuki S, Takahashi Y, Nori S, Nagoshi N, Yagi M, Watanabe K, Nakamura M, Matsumoto M
J Orthop Sci 2023 Nov;28(6):1529-1535. Epub 2021 Oct 30 doi: 10.1016/j.jos.2021.09.008. PMID: 34728111
Resolution of hypoglossal nerve palsy after coil embolization of an anterior condylar confluence fistula.
Detchou DKE, Glauser G, Choudhri OA
Br J Neurosurg 2021 Oct;35(5):562-563. Epub 2021 Aug 2 doi: 10.1080/02688697.2021.1917511. PMID: 34338574
Headache and Hypoglossal Nerve Palsy in a Child With Idiopathic Hypertrophic Pachymeningitis.
Hsieh DT, Faux BM, Lotze TE
Headache 2019 Sep;59(8):1390-1391. Epub 2019 Jul 11 doi: 10.1111/head.13598. PMID: 31294820
Tapia's Syndrome.
Mumtaz S, Henry A, Singh M
Anesth Prog 2018 Summer;65(2):129-130. doi: 10.2344/anpr-65-04-06. PMID: 29952646Free PMC Article
Clinical pearls: headache and hypoglossal nerve palsy.
Dorsey S, Mace S
Acad Emerg Med 2004 Jun;11(6):668-9. PMID: 15175206

Prognosis

Imaging Features of isolated hypoglossal nerve palsy.
Guarnizo A, Glikstein R, Torres C
J Neuroradiol 2020 Mar;47(2):136-150. Epub 2019 Apr 26 doi: 10.1016/j.neurad.2019.04.006. PMID: 31034896
Hypoglossal nerve palsy: 245 cases.
Stino AM, Smith BE, Temkit M, Reddy SN
Muscle Nerve 2016 Dec;54(6):1050-1054. Epub 2016 Nov 1 doi: 10.1002/mus.25197. PMID: 27214783
Lemierre syndrome associated with 12th cranial nerve palsy--a case report and review.
Blessing K, Toepfner N, Kinzer S, Möllmann C, Geiger J, Serr A, Hufnagel M, Müller C, Krüger M, Ridder GJ, Berner R
Int J Pediatr Otorhinolaryngol 2013 Sep;77(9):1585-8. Epub 2013 Jul 8 doi: 10.1016/j.ijporl.2013.05.030. PMID: 23845534
Hypoglossal nerve palsy due to spontaneous dissection of the internal carotid artery.
Ursekar MA, Singhal BS, Konin BL
Clin Radiol 2000 Dec;55(12):978-9. doi: 10.1053/crad.2000.0120. PMID: 11124081
Tongue paralysis following head trauma.
Kacker A, Komisar A, Kakani RS, Reich E, Rothman L
J Laryngol Otol 1995 Aug;109(8):770-1. doi: 10.1017/s0022215100131275. PMID: 7561505

Clinical prediction guides

Complaints and Complications of Microlaryngoscopic Surgery.
Okui A, Konomi U, Watanabe Y
J Voice 2020 Nov;34(6):949-955. Epub 2019 May 31 doi: 10.1016/j.jvoice.2019.05.006. PMID: 31160183
Radiation-induced hypoglossal nerve palsy after definitive radiotherapy for nasopharyngeal carcinoma: Clinical predictors and dose-toxicity relationship.
Chow JCH, Cheung KM, Au KH, Zee BCY, Lee J, Ngan RKC, Lee AWM, Yiu HHY, Li KWS, Leung AKC, Chan JCH, Lee FKH, Wong KH
Radiother Oncol 2019 Sep;138:93-98. Epub 2019 Jun 25 doi: 10.1016/j.radonc.2019.06.011. PMID: 31252300
Diagnostic, Surgical, and Postoperative Challenges of Neuroendocrine Tumors of the Neck: Clinical Experience and Literature Review.
Khan MM, Khan MI, Ali H, Kazmi T, Iqbal H
Ann Vasc Surg 2017 Nov;45:92-97. Epub 2017 Jul 6 doi: 10.1016/j.avsg.2017.06.128. PMID: 28688875
Hypoglossal nerve palsy: 245 cases.
Stino AM, Smith BE, Temkit M, Reddy SN
Muscle Nerve 2016 Dec;54(6):1050-1054. Epub 2016 Nov 1 doi: 10.1002/mus.25197. PMID: 27214783
Hypertrophic pachymeningitis.
Dziedzic T, Wojciechowski J, Nowak A, Marchel A
Childs Nerv Syst 2015 Jul;31(7):1025-31. Epub 2015 Mar 15 doi: 10.1007/s00381-015-2680-z. PMID: 25771924

Recent systematic reviews

Horner's syndrome following obstetric neuraxial blockade - a systematic review of the literature.
Chambers DJ, Bhatia K
Int J Obstet Anesth 2018 Aug;35:75-87. Epub 2018 Mar 17 doi: 10.1016/j.ijoa.2018.03.005. PMID: 29657082
A patient with an odontoid fracture and atrophy of the tongue: a case report and systematic review of the literature.
Kuitwaard K, Vandertop WP
Surg Neurol 2005 Dec;64(6):525-32, discussion 532-3. doi: 10.1016/j.surneu.2005.04.032. PMID: 16293473

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